High impact information on Computers

• Our study was designed to test whether a digital computer program could correctly predict amikacin serum concentrations in the clinical setting [1].
• 99m-Tc-human serum albumin was injected via a central venous catheter into the superior vena cava and precordial activity recorded with a gamma scintillation camera interfaced to a small digital computer [2].
• The method uses orthoiodohippuric acid (hippuran) administered IV, with scintillation imaging, and curve analysis by a digital computer [3].
• Theta/gamma coding therefore bears some relationship to the concept of "word" in digital computers, with word length corresponding to the number of gamma cycles within a theta cycle, and discrete phase corresponding to the ordered "place" within a word [4].
• The initial fluoride distribution was found to be similar to that of [77Br]bromide, a known extracellular-fluid (ECF) tracer, in agreement with the hypothesis underlying the model, and the measured uptake rate in rat bones compared well with the digital computer solution [5].

Biological context of Computers

• Studies of skeletal tracer kinetics. I. Digital-computer solution of a five-compartment model of [18F] fluoride kinetics in humans [6].
• The differential equations for mu and nu as functions of both p and S and, in addition for the rate of glucose consumption as correlated by the yield factors either with the cell growth rate or the rate of ethanol production, were solved properly with a digital computer [7].
• Measurement of labeled [Thr59]IGF-I binding by computer digital image analysis of the autoradiographic images indicated that high affinity IGF-I binding sites are widely distributed at discrete anatomical regions of the brain microarchitecture [8].
• By dynamic simulation of molecular structures in a digital computer, search was made for all possible ways of superposing a phenyl ring of a tricyclic antidepressant on the phenyl ring of norepinephrine [9].
• The purpose of this study was to examine the effect of manidipine hydrochloride, a new calcium antagonist, on renal blood flow in healthy subjects, using the newly developed pulsed-Doppler flowmeter with colored flow imager and digital computer analyzer [10].

Anatomical context of Computers

• Bromsulphalein plasma kinetics after obstruction of the common bile duct in rats: curve fitting with a programmable calculator [11].

Associations of Computers with chemical compounds

• A system for individualized dosing of intravenous aminophylline using a programmable calculator [12].
• A glucose control system consisting of a single in-line glucose sensor, concentrated glucose solution, and computer hardware and software were developed [13].
• Five trained mongrel dogs breathed from a mask as the inspired gas was alternated between air and O2 for multiple cycles, and continuous time series records of HR and oxyhemoglobin saturation were recorded on a digital computer and analyzed by the technique of ensemble averaging [14].
• Image data taken by the CCD camera were fed into a desktop digital computer; then the fractal dimension of each skin cross section was determined on the basis of the box-counting algorithm [15].
• Evaluation of environmental polychlorobiphenyls and DDE in terms of mixtures of commercial preparations from peak heights of packed-column gas chromatograms using a programmable calculator [16].

Gene context of Computers

• Color images obtained directly from the CRT display of a digital computer were used to assess the passage of radionuclides through the heart [17].
• This paper describes the incorporation of a SMAC (Technicon) analyzer into data-processing techniques that have been developed on existing computer hardware during several years [18].
• Bedside determination of bicarbonate and base excess, blood oxygen saturation and content, VD/VT, and P50 using a programmable calculator [19].
• Epidemiologic programs for computers and calculators. Simple algorithms for the representation of deterministic and stochastic versions of the Reed-Frost epidemic model using a programmable calculator [20].
• Direct curve-fitting methods using a digital computer have been employed to analyze the calibration curves of commercial kits for the assay of digoxin, digitoxin, insulin, B12, and renin activity (angiotensin) [21].

Analytical, diagnostic and therapeutic context of Computers

• Compartmental analysis of plasma paracetamol concentrations following intravenous injection of 12 mg kg-1 in aqueous solution to normal subjects was performed using analogue and digital computer methods [22].
• Single stage semi-automated radioimmunoassays for total serum thyroxine (T4) and triiodothyronine (T3) are described which employ an automatic pipetting station, automatic gamma counter, and a programmable calculator with paper tape reader and printing facility [23].
• A handheld programmable calculator was used to increase speed and decrease errors when calculating and labeling total parenteral nutrition formulations for pediatric patients [24].
• Recent advances in CT scanner technology and computer hardware have led to the development of CT fluoroscopy (CTF), which allows real-time acquisition and display of cross-sectional images (with a rate of up to 8 frames per second) [25].

References