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Chemical Compound Review

AR-1L7363     2,2,2-trifluoroethanone

Synonyms: CF3C(O), AC1L3W5O, Trifluoroacetyl, 25733-EP2270018A1, 25733-EP2277881A1, ...
 
 
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Disease relevance of Trifluoroacetyl

  • Comparative immunoreactivity of anti-trifluoroacetyl (TFA) antibody and anti-lipoic acid antibody in primary biliary cirrhosis: searching for a mimic [1].
  • Eighteen trifluoroacetyl derivatives of amino acids and of amino acid analogs were prepared and tested for growth-inhibitory activity using a Lactobacillus casei system as a prescreen for antitumor activity [2].
 

High impact information on Trifluoroacetyl

 

Biological context of Trifluoroacetyl

 

Anatomical context of Trifluoroacetyl

 

Associations of Trifluoroacetyl with other chemical compounds

 

Gene context of Trifluoroacetyl

 

Analytical, diagnostic and therapeutic context of Trifluoroacetyl

References

  1. Comparative immunoreactivity of anti-trifluoroacetyl (TFA) antibody and anti-lipoic acid antibody in primary biliary cirrhosis: searching for a mimic. Sasaki, M., Ansari, A., Pumford, N., van de Water, J., Leung, P.S., Humphries, K.M., Szweda, L.I., Nakanuma, Y., Roche, T.E., Coppel, R.L., Bach, J.F., Gershwin, M.E. J. Autoimmun. (2000) [Pubmed]
  2. Effect of N-trifluoroacetyl derivatives of amino acids and amino acid analogs on microbial antitumor screen. Otani, T.T., Briley, M.R. Journal of pharmaceutical sciences. (1979) [Pubmed]
  3. Epidemic of liver disease caused by hydrochlorofluorocarbons used as ozone-sparing substitutes of chlorofluorocarbons. Hoet, P., Graf, M.L., Bourdi, M., Pohl, L.R., Duray, P.H., Chen, W., Peter, R.M., Nelson, S.D., Verlinden, N., Lison, D. Lancet (1997) [Pubmed]
  4. Processing of endoplasmic reticulum luminal antigens associated with halothane hepatitis in rat hepatocytes. Amouzadeh, H.R., Pohl, L.R. Hepatology (1995) [Pubmed]
  5. Inhibition of human leukocyte elastase by acetyl and trifluoroacetyl oligopeptide chloromethyl ketones. Lestienne, P., Dimicoli, J.L., Renaud, A., Bieth, J.G. J. Biol. Chem. (1979) [Pubmed]
  6. Mechanisms of halothane toxicity: novel insights. Gut, J., Christen, U., Huwyler, J. Pharmacol. Ther. (1993) [Pubmed]
  7. Solid-phase parallel synthesis of 17alpha-substituted estradiol sulfamate and phenol libraries using the multidetachable sulfamate linker. Ciobanu, L.C., Poirier, D. Journal of combinatorial chemistry. (2003) [Pubmed]
  8. Human hepatocytes express trifluoroacetylated neoantigens after in vitro exposure to halothane. Ilyin, G.P., Rissel, M., Malledant, Y., Tanguy, M., Guillouzo, A. Biochem. Pharmacol. (1994) [Pubmed]
  9. Incorporation of N2-deoxyguanosine metabolic adducts of 2-aminonaphthalene and 2-aminofluorene into oligomeric DNA. Bonala, R.R., Torres, M.C., Attaluri, S., Iden, C.R., Johnson, F. Chem. Res. Toxicol. (2005) [Pubmed]
  10. Kinetics and thermodynamics of amine and diamine signaling by a trifluoroacetyl azobenzene reporter group. Mertz, E., Beil, J.B., Zimmerman, S.C. Org. Lett. (2003) [Pubmed]
  11. Analytical methods for monoterpene glycosides in grape and wine. II. Qualitative and quantitative determination of monoterpene glycosides in grape. Voirin, S.G., Baumes, R.L., Sapis, J.C., Bayonove, C.L. J. Chromatogr. (1992) [Pubmed]
  12. Interaction of lymphocytes with Kupffer cells from halothane-exposed guinea pigs. Furst, S.M., Gandolfi, A.J. Int. Arch. Allergy Immunol. (1997) [Pubmed]
  13. An enzyme kinetics and 19F nuclear magnetic resonance study of selectively trifluoroacetylated cytochrome c derivatives. Staudenmayer, N., Smith, M.B., Smith, H.T., Spies, F.K., Millett, F. Biochemistry (1976) [Pubmed]
  14. Immunological studies on the mechanism of halothane-induced hepatotoxicity: immunohistochemical evidence of trifluoroacetylated hepatocytes. Satoh, H., Fukuda, Y., Anderson, D.K., Ferrans, V.J., Gillette, J.R., Pohl, L.R. J. Pharmacol. Exp. Ther. (1985) [Pubmed]
  15. Kupffer cells from halothane-exposed guinea pigs carry trifluoroacetylated protein adducts. Furst, S.M., Luedke, D., Gandolfi, A.J. Toxicology (1997) [Pubmed]
  16. 19F NMR of trifluoroacetyl-labeled cysteine mutants of myoglobin: structural probes of nitric oxide bound to the H93G cavity mutant. Thomas, M.R., Boxer, S.G. Biochemistry (2001) [Pubmed]
  17. Efficient protocol for ring opening of spiroketals using trifluoroacetyl trifluoromethanesulfonate (TFAT). Lee, J.S., Fuchs, P.L. Org. Lett. (2003) [Pubmed]
  18. Gas-liquid chromatographic method for the measurement of methyl urea in blood and urine. Evans, R.T. J. Chromatogr. (1976) [Pubmed]
  19. Mass fragmentographic determination of 4-hydroxy-3-methoxyphenylglycol (HMPG) in urine, cerebrospinal fluid, plasma and tissues using a deuterium-labelled internal standard. Sjöquist, B., Lindström, B., Anggård, E. J. Chromatogr. (1975) [Pubmed]
  20. A novel model of drug hapten-induced hepatitis with increased mast cells in the BALB/c mouse. Njoku, D.B., Talor, M.V., Fairweather, D., Frisancho-Kiss, S., Odumade, O.A., Rose, N.R. Exp. Mol. Pathol. (2005) [Pubmed]
  21. On the inhibition of human leukocyte elastase by trifluoroacetyl tripeptides. Dimicoli, J.L., Bieth, J. J. Biol. Chem. (1978) [Pubmed]
  22. Capillary gas chromatographic separation of bile acid acyl glycosides without thermal decomposition and isomerization. Iida, T., Ogawa, S., Kakiyama, G., Goto, T., Mano, N., Goto, J., Nambara, T. Journal of chromatography. A. (2004) [Pubmed]
  23. Preparation and application of an affinity matrix for phosphatidylinositol-specific phospholipase C. Shashidhar, M.S., Keana, J.F., Volwerk, J.J., Griffith, O.H. Chem. Phys. Lipids (1990) [Pubmed]
  24. Antibody assays for the detection of patients sensitized to halothane. Martin, J.L., Kenna, J.G., Pohl, L.R. Anesth. Analg. (1990) [Pubmed]
  25. Headspace gas chromatography of stimulants in urine by in-column trifluoroacetyl derivatization method. Tsuchihashi, H., Nakajima, K., Nishikawa, M., Shiomi, K., Takahashi, S. J. Chromatogr. (1989) [Pubmed]
 
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