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Chemical Compound Review

Deccox     ethyl6-decoxy-7-ethoxy-4-oxo- 1H-quinoline...

Synonyms: Decoxy, DECOQUINATE, Decoquinato, Decoquinatum, PubChem2446, ...
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Disease relevance of Deccox


High impact information on Deccox


Chemical compound and disease context of Deccox


Biological context of Deccox


Anatomical context of Deccox

  • The results showed that continuous medication with decoquinate was effective in preventing the transfer of sporozoites from the intestine to the liver [13].
  • All calves, except 2 controls necropsied 14 DAI and 4 calves given decoquinate, discharged moderate-to-large numbers of oocysts in feces and had moderate-to-serve changes in fecal consistency [14].
  • We examined human foreskin fibroblast cell cultures infected with the normally tissue cyst-less RH strain of Toxoplasma gondii and treated with decoquinate for evidence of tissue cyst induction and formation [15].
  • Lymphocytes from steers of the decoquinate-fed group had decreased random migration under agarose, enhanced cytochrome C reduction, and enhanced iodination activity [10].

Associations of Deccox with other chemical compounds


Gene context of Deccox


Analytical, diagnostic and therapeutic context of Deccox


  1. Effects of intermittent and continuous administration of decoquinate on bovine coccidiosis in male calves. Fitzgerald, P.R., Mansfield, M.E. Am. J. Vet. Res. (1989) [Pubmed]
  2. Influence of decoquinate on ruminal fermentation, diet digestibility and cattle performance. Harmon, D.L., Nagaraja, T.G., Brandt, R.T., Lee, R.W., Avery, T.B. J. Anim. Sci. (1987) [Pubmed]
  3. Effect of different decoquinate treatments on cryptosporidiosis in naturally infected cashmere goat kids. Ferre, I., Benito-Peña, A., García, U., Osoro, K., Ortega-Mora, L.M. Vet. Rec. (2005) [Pubmed]
  4. Decoquinate and the control of experimental ovine toxoplasmosis. Buxton, D., Brebner, J., Wright, S., Maley, S.W., Thomson, K.M., Millard, K. Vet. Rec. (1996) [Pubmed]
  5. Evaluation of decoquinate, lasalocid, and monensin against experimentally induced sarcocystosis in calves. Foreyt, W.J. Am. J. Vet. Res. (1986) [Pubmed]
  6. Effects of decoquinate and clopidol on electron transport in mitochondria of Eimeria tenella (Apicomplexa: Coccidia). Fry, M., Williams, R.B. Biochem. Pharmacol. (1984) [Pubmed]
  7. Effect of the quinolone coccidiostat decoquinate on the rearrangement of chromosomes of Eimeria tenella. Del Cacho, E., Gallego, M., Pages, M., Monteagudo, L., S??nchez-Acedo, C. Int. J. Parasitol. (2006) [Pubmed]
  8. Tracing the emergence of drug-resistance in coccidia (Eimeria spp.) of commercial broiler flocks medicated with decoquinate for the first time in the United Kingdom. Williams, R.B. Vet. Parasitol. (2006) [Pubmed]
  9. Efficacy of lasalocid and decoquinate against coccidiosis in naturally infected dairy calves. Waggoner, J.K., Cecava, M.J., Kazacos, K.R. J. Dairy Sci. (1994) [Pubmed]
  10. Alteration of neutrophil function associated with coccidiosis in cattle: influence of decoquinate and dexamethasone. Roth, J.A., Jarvinen, J.A., Frank, D.E., Fox, J.E. Am. J. Vet. Res. (1989) [Pubmed]
  11. Field study of the efficacy of halofuginone and decoquinate in the treatment of cryptosporidiosis in veal calves. Lallemand, M., Villeneuve, A., Belda, J., Dubreuil, P. Vet. Rec. (2006) [Pubmed]
  12. Development by genetic recombination of a line of Eimeria tenella resistant to robenidine, decoquinate and amprolium. Chapman, H.D. Zeitschrift für Parasitenkunde (Berlin, Germany) (1984) [Pubmed]
  13. The extraintestinal stages of Eimeria tenella and E. maxima in the chicken. Perry, E.A., Long, P.L. Vet. Parasitol. (1987) [Pubmed]
  14. Effects of inoculations with Eimeria zuernii on young calves treated with decoquinate or narasin with or without dexamethasone. Fitzgerald, P.R., Mansfield, M.E. Am. J. Vet. Res. (1989) [Pubmed]
  15. Decoquinate induces tissue cyst formation by the RH strain of Toxoplasma gondii. Lindsay, D.S., Toivio-Kinnucan, M.A., Blagburn, B.L. Vet. Parasitol. (1998) [Pubmed]
  16. Evaluation of lasalocid and decoquinate against coccidiosis resulting from natural exposure in weaned dairy calves. Hoblet, K.H., Charles, T.P., Howard, R.R. Am. J. Vet. Res. (1989) [Pubmed]
  17. Evaluation of lasalocid as a coccidiostat in calves: titration, efficacy, and comparison with monensin and decoquinate. Foreyt, W.J., Rice, D.H., Wescott, R.B. Am. J. Vet. Res. (1986) [Pubmed]
  18. Evaluation of decoquinate to treat experimental cryptosporidiosis in kids. Mancassola, R., Richard, A., Naciri, M. Vet. Parasitol. (1997) [Pubmed]
  19. Cytochrome b mutation identified in a decoquinate-resistant mutant of Toxoplasma gondii. McFadden, D.C., Boothroyd, J.C. J. Eukaryot. Microbiol. (1999) [Pubmed]
  20. Activity of decoquinate against Cryptosporidium parvum in cell cultures and neonatal mice. Lindsay, D.S., Woods, K.M., Upton, S.J., Blagburn, B.L. Vet. Parasitol. (2000) [Pubmed]
  21. Protozoan infections (Toxoplasma gondii, Neospora caninum and Sarcocystis spp.) in sheep and goats: recent advances. Buxton, D. Vet. Res. (1998) [Pubmed]
  22. Prophylactic use of decoquinate for infections with Cryptosporidium parvum in experimentally challenged neonatal calves. Moore, D.A., Atwill, E.R., Kirk, J.H., Brahmbhatt, D., Herrera Alonso, L., Hou, L., Singer, M.D., Miller, T.D. J. Am. Vet. Med. Assoc. (2003) [Pubmed]
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