Chemical Compound Review:
Cefditoren (6R)-7-[[(2Z)-2-(2-amino-1,3- thiazol-4-yl)...
Synonyms:
- Cefditoren pivoxil: a review of its use in the treatment of bacterial infections. Wellington, K., Curran, M.P. Drugs (2004)
- Cefditoren pivoxil. Darkes, M.J., Plosker, G.L. Drugs (2002)
- Impact on carnitine homeostasis of short-term treatment with the pivalate prodrug cefditoren pivoxil. Brass, E.P., Mayer, M.D., Mulford, D.J., Stickler, T.K., Hoppel, C.L. Clin. Pharmacol. Ther. (2003)
- Effects of amino acid alterations in penicillin-binding proteins (PBPs) 1a, 2b, and 2x on PBP affinities of penicillin, ampicillin, amoxicillin, cefditoren, cefuroxime, cefprozil, and cefaclor in 18 clinical isolates of penicillin-susceptible, -intermediate, and -resistant pneumococci. Nagai, K., Davies, T.A., Jacobs, M.R., Appelbaum, P.C. Antimicrob. Agents Chemother. (2002)
- Are {beta}-lactam breakpoints adequate to define non-susceptibility for all Haemophilus influenzae resistance phenotypes from a pharmacodynamic point of view? Alou, L., Giménez, M.J., Sevillano, D., Aguilar, L., González, N., Echeverría, O., Torrico, M., Coronel, P., Prieto, J. J. Antimicrob. Chemother. (2007)
- In vitro susceptibility of recent clinical isolates of pneumococci to the investigational cephalosporin cefditoren. Karlowsky, J.A., Jones, M.E., Draghi, D.C., Critchley, I.A., Thornsberry, C., Sahm, D.F. Diagn. Microbiol. Infect. Dis. (2002)
- Randomized, double-blind, multicenter comparison of oral cefditoren 200 or 400 mg BID with either cefuroxime 250 mg BID or cefadroxil 500 mg BID for the treatment of uncomplicated skin and skin-structure infections. Bucko, A.D., Hunt, B.J., Kidd, S.L., Hom, R. Clinical therapeutics. (2002)
- Antimicrobial activity and in vitro susceptibility test development for cefditoren against Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus species. Johnson, D.M., Biedenbach, D.J., Beach, M.L., Pfaller, M.A., Jones, R.N. Diagn. Microbiol. Infect. Dis. (2000)
- In vitro antibacterial activity of FK041, a new orally active cephalosporin. Watanabe, Y., Hatano, K., Matsumoto, Y., Tawara, S., Yamamoto, H., Kawabata, K., Takasugi, H., Matsumoto, F., Kuwahara, S. J. Antibiot. (1999)
- Time-kill studies on susceptibility of nine penicillin-susceptible and -resistant pneumococci to cefditoren compared with nine other beta-lactams. Spangler, S.K., Jacobs, M.R., Appelbaum, P.C. J. Antimicrob. Chemother. (1997)
- Review of cefditoren, an advanced-generation, broad-spectrum oral cephalosporin. Guay, D.R. Clinical therapeutics. (2001)
- Cefditoren in vitro activity and spectrum: a review of international studies using reference methods. Jones, R.N., Pfaller, M.A., Jacobs, M.R., Appelbaum, P.C., Fuchs, P.C. Diagn. Microbiol. Infect. Dis. (2001)
- Determination of the changes in surface energetics of cefditoren pivoxil as a consequence of processing induced disorder and equilibration to different relative humidities. Ohta, M., Buckton, G. International journal of pharmaceutics. (2004)
- Simultaneous intravenous and intramiddle-ear dosing to determine cefditoren influx and efflux clearances in middle ear fluid in freely moving chinchillas. Zhu, T., Cheung, B.W., Cartier, L.L., Giebink, G.S., Sawchuk, R.J. Journal of pharmaceutical sciences. (2003)
- Cefditoren pivoxil versus cefpodoxime proxetil for community-acquired pneumonia: results of a multicenter, prospective, randomized, double-blind study. van Zyl, L., le Roux, J.G., LaFata, J.A., Volk, R.S., Palo, W.A., Flamm, R., Hom, R.C. Clinical therapeutics. (2002)
- Cefditoren activity against nearly 1000 non-fastidious bacterial isolates and the development of in vitro susceptibility test methods. Jones, R.N., Biedenbach, D.J., Johnson, D.M. Diagn. Microbiol. Infect. Dis. (2000)
- An in vitro characterization of cefditoren, a new oral cephalosporin. Felmingham, D., Robbins, M.J., Ghosh, G., Bhogal, H., Mehta, M.D., Leakey, A., Clark, S., Dencer, C.A., Ridgway, G.L., Grüneberg, R.N. Drugs under experimental and clinical research. (1994)
- Phase I clinical trial of cefditoren pivoxil (ME 1207): pharmacokinetics in healthy volunteers. Li, J.T., Hou, F., Lu, H., Li, T.Y., Li, H. Drugs under experimental and clinical research. (1997)
- Determination of cefditoren (ME 1206) in the plasma of elderly patients with multiple diseases using high-performance liquid chromatography. Rieck, W., Platt, D. Clin. Lab. (2000)
- Quantification of the cephalosporin antibiotic cefditoren in human plasma by high-performance liquid chromatography. Nirogi, R.V., Kandikere, V.N., Shrivastava, W., Mudigonda, K. Arzneimittel-Forschung. (2006)
- The use of inverse gas chromatography to assess the acid-base contributions to surface energies of cefditoren pivoxil and methacrylate copolymers and possible links to instability. Ohta, M., Buckton, G. International journal of pharmaceutics. (2004)
- Differentiation of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae from other H. influenzae strains by a disc method. Ubukata, K., Chiba, N., Hasegawa, K., Shibasaki, Y., Sunakawa, K., Nonoyama, M., Iwata, S., Konno, M. J. Infect. Chemother. (2002)