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Chemical Compound Review

AC1O5PIQ     (2E,4E,6E,8E,10E)-docosa- 2,4,6,8,10...

Synonyms: LMFA04000049, C22:5n-12,14,16,18,20, Docosapentaenoic acid (VAN), 2E,4E,6E,8E,10E-docosapentaenoic acid
 
 
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Disease relevance of docosapentaenoic acid

 

Psychiatry related information on docosapentaenoic acid

 

High impact information on docosapentaenoic acid

 

Biological context of docosapentaenoic acid

 

Anatomical context of docosapentaenoic acid

 

Associations of docosapentaenoic acid with other chemical compounds

 

Gene context of docosapentaenoic acid

 

Analytical, diagnostic and therapeutic context of docosapentaenoic acid

  • The decrease was accompanied by an increase in docosapentaenoic acid (22:5n-6) content, which replaced the 22:6n-3 phospholipids with 22:5n-6 molecular species, as demonstrated using HPLC/electrospray mass spectrometry [32].

References

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  6. An extraordinary degree of structural specificity is required in neural phospholipids for optimal brain function: n-6 docosapentaenoic acid substitution for docosahexaenoic acid leads to a loss in spatial task performance. Lim, S.Y., Hoshiba, J., Salem, N. J. Neurochem. (2005) [Pubmed]
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  9. n-6 Docosapentaenoic acid is not a predictor of low docosahexaenoic acid status in Canadian preschool children. Innis, S.M., Vaghri, Z., King, D.J. Am. J. Clin. Nutr. (2004) [Pubmed]
  10. Supplementing lactating women with flaxseed oil does not increase docosahexaenoic acid in their milk. Francois, C.A., Connor, S.L., Bolewicz, L.C., Connor, W.E. Am. J. Clin. Nutr. (2003) [Pubmed]
  11. Significantly reduced docosahexaenoic and docosapentaenoic acid concentrations in erythrocyte membranes from schizophrenic patients compared with a carefully matched control group. Assies, J., Lieverse, R., Vreken, P., Wanders, R.J., Dingemans, P.M., Linszen, D.H. Biol. Psychiatry (2001) [Pubmed]
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  19. Rabbit photoreceptor outer segments contain high levels of docosapentaenoic acid. Nielsen, J.C., Maude, M.B., Hughes, H., Anderson, R.E. Invest. Ophthalmol. Vis. Sci. (1986) [Pubmed]
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  21. N-3 fatty acid deficiency in the rat pineal gland: effects on phospholipid molecular species composition and endogenous levels of melatonin and lipoxygenase products. Zhang, H., Hamilton, J.H., Salem, N., Kim, H.Y. J. Lipid Res. (1998) [Pubmed]
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  23. Low-dose eicosapentaenoic or docosahexaenoic acid administration modifies fatty acid composition and does not affect susceptibility to oxidative stress in rat erythrocytes and tissues. Calviello, G., Palozza, P., Franceschelli, P., Bartoli, G.M. Lipids (1997) [Pubmed]
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  30. Effect of exercise on FA profiles in n-3 FA-supplemented and -nonsupplemented premenopausal women. Conquer, J.A., Roelfsema, H., Zecevic, J., Graham, T.E., Holub, B.J. Lipids (2002) [Pubmed]
  31. Evidence of increased flux to n-6 docosapentaenoic acid in phospholipids of pancreas from cftr-/- knockout mice. Ollero, M., Laposata, M., Zaman, M.M., Blanco, P.G., Andersson, C., Zeind, J., Urman, Y., Kent, G., Alvarez, J.G., Freedman, S.D. Metab. Clin. Exp. (2006) [Pubmed]
  32. Effect of docosahexaenoic acid on the synthesis of phosphatidylserine in rat brain in microsomes and C6 glioma cells. Garcia, M.C., Ward, G., Ma, Y.C., Salem, N., Kim, H.Y. J. Neurochem. (1998) [Pubmed]
 
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