Disease relevance of Pitressin

• Effect of 8-arginine-vasopressin during adaptation to hyperthermia [1].

High impact information on Pitressin

• F-MLVP, MA-MLVP, and R-MLVP effectively competed for 8-arginine vasopressin (AVP)-binding sites in canine renal plasma membranes and on the surface of porcine kidney cells (LLC-PK1, ATCC CL101) [2].
• The actions of [8-arginine] vasopressin (AVP) on liver cells were also inhibited by PMA, but the inhibition could be overcome by high AVP concentrations [3].
• A route for fetal 8-arginine vasopressin (AVP) clearance has not yet been established [4].
• Similar maximal responses were observed with 8-arginine vasopressin (AVP), oxytocin, and 8-lysine vasopressin, although the potencies of these hormones diminished in the order listed above [5].
• A method for screening monoclonal antibodies (McAbs) to neuropeptides was evaluated using 8-arginine-vasopressin (AVP) as a model [6].

Biological context of Pitressin

• The possibility that the release of 8-arginine vasopressin was responsible for the rise in blood pressure was explored [7].
• Effects of argipressin injected into medial amygdaloid body on blood pressure and heart rate in rats [8].
• Binding sites of ZNC(C)PR, a pentapeptide fragment of argipressin, in rat brain [9].
• AIM: To study the signal transduction pathway induced by argipressin (4-8) (AVP4-8) in rat hippocampus [10].
• The effects of 30-min intravenous infusions of 8-arginine vasopressin (AVP) and angiotensin-(1,8)-octapeptide (ANG II) to conscious dogs were studied by measurements of systolic (SABP), mean (MABP), and diastolic arterial blood pressures, central venous pressure (CVP), heart rate (HR), and plasma concentrations of vasopressin (pAVP) [11].

Anatomical context of Pitressin

• We have previously reported that 8-arginine vasopressin (AVP) stimulates phosphatidylinositol turnover and Ca++ mobilization in rat aortic smooth muscle cells (A10) [12].
• 1. The assessment of the role of hair follicles and sweat glands in skin resistance and percutaneous iontophoretic flux of 9-desglycinamide, 8-arginine vasopressin (DGAVP) by comparing two skin species: human stratum corneum which contained hair follicles, sweat and sebaceous glands, and shed snake skin which lacked all appendages [13].
• Cardiovascular effects of injection of argipressin into lateral septal nuclei in rats [14].
• Cytosolic Ca2+ concentrations ([Ca2+]cyt) and [3H]inositol phosphates ([3H]InsP) were correlated while decreasing the Ca2+ content of sarcoplasmic reticulum (SR) stores in cultured A7r5 cells at rest and after activation with 8-arginine vasopressin (AVP) [15].
• AIM: To study the effect of argipressin (4-8) (AVP4-8) on the mitogen-activated protein kinase (MAPK) activity in astroglial culture and fetal neuronal culture from rat cerebral cortex and hippocampus [16].

Associations of Pitressin with other chemical compounds

• Radioimmunoassay of 8-arginine-vasopressin (antidiuretic hormone) in human plasma [17].
• Average values (+/- SE) for induction of a half-maximal urea permeability response in toads from all seasons were 1.4 +/- 0.3 X 10(-10) M for AVT, 7.4 +/- 1.5 X 10(-9) M for 8-arginine vasopressin, and 2.9 +/- 0.6 X 10(-8) M for oxytocin [18].
• In stressed and unstressed animals, the number of androgen receptors and arginine vasopressin-expressing neurons in both of these nuclei correlated negatively with corticosterone concentrations in plasma and Fos levels in the paraventricular nucleus [19].

Gene context of Pitressin

• Effect of 8-arginine vasopressin (AVP) was examined on human platelet membrane GTPase activity as an index of a G-protein involvement [20].
• Upon the treatment of cells with 8-arginine-vasopressin (AVP), a significant increase in the surface level of P-LAP was observed [21].
• The actions of glucagon on hepatocytes were inhibited by pretreatment of cells with 10 nM [8-arginine] vasopressin [22].
• This paper describes the production and evaluation of an antiserum with high affinity (Ka = 1.9 X 10(11) l/mol) and specifity to 8-arginine-vasopressin (AVP) [23].
• Involvement of a putative G-protein-coupled receptor and a branching pathway in argipressin (4-8) signal transduction in rat hippocampus [10].

Analytical, diagnostic and therapeutic context of Pitressin

• 9. The presence of neurohormone(s), assessed by radioimmunoassay for [8-arginine] vasopressin, was also demonstrated [24].
• A homogeneous peptide, which shared an identical retention time (RT) and amino acid sequence with synthetic 8-arginine vasopressin (AVP), was isolated by serial semipreparative high performance liquid chromatography [25].

References