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Chemical Compound Review

GNF-Pf-5041     2,3,5-triphenyl-1,3,4-triaza- 2...

Synonyms: SureCN491438, CBDivE_016098, CCG-103300, IFLab1_000263, AC1L1SQG, ...
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  • However, infarct size (assessed by triphenyltetrazolium staining) in the circumflex preconditioned group averaged 4 +/- 1% of the myocardium at risk, significantly less (p < 0.05) than the value of 13 +/- 4% observed in the concurrent controls [6].
  • After the dog was killed, the left ventricle was sliced from apex to base, and any infarct was outlined with triphenyltetrazolium (TTC) staining [7].
  • SOD + catalase had no significant beneficial effect on infarct size measured by triphenyltetrazolium staining: area of necrosis averaged 38.5 +/- 6.1% vs. 46.3 +/- 6.2% of the area at risk in treated compared with control animals respectively (p = NS) [8].
  • Triphenyltetrazolium staining of irreversible ischemic injury following coronary artery occlusion in rats [9].
  • Triphenyltetrazolium-determined injury volume of the ipsilateral cerebral cortex (control, 40+/-7%; bFGF 5 microg/kg per hour, 22+/-5%; bFGF 50 microg/kg per hour, 26+/-7%; bFGF 255 microg/kg per hour, 23+/-6% of ipsilateral cerebral cortex; mean+/-SEM) was less in cats treated with bFGF [10].

Chemical compound and disease context of TRIPHENYLTETRAZOLIUM CHLORIDE






Associations of TRIPHENYLTETRAZOLIUM CHLORIDE with other chemical compounds




Analytical, diagnostic and therapeutic context of TRIPHENYLTETRAZOLIUM CHLORIDE


  1. Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. Marber, M.S., Mestril, R., Chi, S.H., Sayen, M.R., Yellon, D.M., Dillmann, W.H. J. Clin. Invest. (1995) [Pubmed]
  2. Adenosine receptor involvement in a delayed phase of myocardial protection 24 hours after ischemic preconditioning. Baxter, G.F., Marber, M.S., Patel, V.C., Yellon, D.M. Circulation (1994) [Pubmed]
  3. PPBP [4-phenyl-1-(4-phenylbutyl) piperidine] decreases brain injury after transient focal ischemia in rats. Takahashi, H., Kirsch, J.R., Hashimoto, K., London, E.D., Koehler, R.C., Traystman, R.J. Stroke (1996) [Pubmed]
  4. Sustained decrease in brain regional blood flow after microsphere embolism in rats. Miyake, K., Takeo, S., Kaijihara, H. Stroke (1993) [Pubmed]
  5. Isoflurane protects against myocardial infarction during early reperfusion by activation of phosphatidylinositol-3-kinase signal transduction: evidence for anesthetic-induced postconditioning in rabbits. Chiari, P.C., Bienengraeber, M.W., Pagel, P.S., Krolikowski, J.G., Kersten, J.R., Warltier, D.C. Anesthesiology (2005) [Pubmed]
  6. Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion. Przyklenk, K., Bauer, B., Ovize, M., Kloner, R.A., Whittaker, P. Circulation (1993) [Pubmed]
  7. The use of preintervention and postintervention thallium imaging for assessing the early and late effects of experimental coronary arterial reperfusion in dogs. Okada, R.D., Pohost, G.M. Circulation (1984) [Pubmed]
  8. "Reperfusion injury" by oxygen-derived free radicals? Effect of superoxide dismutase plus catalase, given at the time of reperfusion, on myocardial infarct size, contractile function, coronary microvasculature, and regional myocardial blood flow. Przyklenk, K., Kloner, R.A. Circ. Res. (1989) [Pubmed]
  9. Triphenyltetrazolium staining of irreversible ischemic injury following coronary artery occlusion in rats. Vivaldi, M.T., Kloner, R.A., Schoen, F.J. Am. J. Pathol. (1985) [Pubmed]
  10. Intravenous basic fibroblast growth factor decreases brain injury resulting from focal ischemia in cats. Bethel, A., Kirsch, J.R., Koehler, R.C., Finklestein, S.P., Traystman, R.J. Stroke (1997) [Pubmed]
  11. Effects of naftidrofuryl oxalate on microsphere embolism-induced decrease in regional blood flow of rat brain. Miyake, K., Takagi, N., Takeo, S. Br. J. Pharmacol. (1994) [Pubmed]
  12. Myocardial protection after monophosphoryl lipid A: studies of delayed anti-ischaemic properties in rabbit heart. Baxter, G.F., Goodwin, R.W., Wright, M.J., Kerac, M., Heads, R.J., Yellon, D.M. Br. J. Pharmacol. (1996) [Pubmed]
  13. Reduction of myocardial infarct size by poloxamer 188 and mannitol in a canine model. Justicz, A.G., Farnsworth, W.V., Soberman, M.S., Tuvlin, M.B., Bonner, G.D., Hunter, R.L., Martino-Saltzman, D., Sink, J.D., Austin, G.E. Am. Heart J. (1991) [Pubmed]
  14. Direct, longitudinal comparison of (1)H and (23)Na MRI after transient focal cerebral ischemia. Lin, S.P., Song, S.K., Miller, J.P., Ackerman, J.J., Neil, J.J. Stroke (2001) [Pubmed]
  15. Detection of viable myocardium by low dose of dobutamine cine MR imaging in miniswine. Lu, M., Zhao, S., Wei, Y., Wang, C., Jiang, S., Huang, L., Zhang, Y., Mou, F., Meng, L., Ruan, Y. Chin. Med. J. (2003) [Pubmed]
  16. Preconditioning delays Ca2+-induced mitochondrial permeability transition. Argaud, L., Gateau-Roesch, O., Chalabreysse, L., Gomez, L., Loufouat, J., Thivolet-Béjui, F., Robert, D., Ovize, M. Cardiovasc. Res. (2004) [Pubmed]
  17. Isoflurane preconditions myocardium against infarction via release of free radicals. Müllenheim, J., Ebel, D., Frässdorf, J., Preckel, B., Thämer, V., Schlack, W. Anesthesiology (2002) [Pubmed]
  18. Role of delta-opioid receptor agonists on infarct size reduction in swine. Sigg, D.C., Coles, J.A., Oeltgen, P.R., Iaizzo, P.A. Am. J. Physiol. Heart Circ. Physiol. (2002) [Pubmed]
  19. Clentiazem given at reperfusion improves subendocardial reflow and reduces myocardial infarct size in the dog. Rousseau, G., Provost, P., Tran, D., Caillé, G., Latour, J.G. J. Pharmacol. Exp. Ther. (1994) [Pubmed]
  20. Hippurate hydrolysis by and triphenyltetrazolium tolerance of Campylobacter fetus. Luechtefeld, N.W., Wang, W.L. J. Clin. Microbiol. (1982) [Pubmed]
  21. Competitive N-methyl-D-aspartate receptor blockade reduces brain injury following transient focal ischemia in cats. Nishikawa, T., Kirsch, J.R., Koehler, R.C., Miyabe, M., Traystman, R.J. Stroke (1994) [Pubmed]
  22. Genetic hypertension and increased susceptibility to cerebral ischemia. Barone, F.C., Price, W.J., White, R.F., Willette, R.N., Feuerstein, G.Z. Neuroscience and biobehavioral reviews. (1992) [Pubmed]
  23. Neuroprotective effect of hyperbaric oxygen therapy monitored by MR-imaging after embolic stroke in rats. Henninger, N., Küppers-Tiedt, L., Sicard, K.M., Günther, A., Schneider, D., Schwab, S. Exp. Neurol. (2006) [Pubmed]
  24. Halothane reduces reperfusion injury after regional ischaemia in the rabbit heart in vivo. Schlack, W., Preckel, B., Barthel, H., Obal, D., Thämer, V. British journal of anaesthesia. (1997) [Pubmed]
  25. Reduction in myocardial infarct size by the new potassium channel opener bimakalim. Auchampach, J.A., Gross, G.J. J. Cardiovasc. Pharmacol. (1994) [Pubmed]
  26. Lignocaine in experimental myocardial infarction: failure to prevent neutrophil accumulation and ventricular fibrillation and to reduce infarct size. de Lorgeril, M., Rousseau, G., Basmadjian, A., Latour, J.G. Cardiovasc. Res. (1988) [Pubmed]
  27. L-Arginine administration prevents reperfusion-induced cardiomyocyte hypercontracture and reduces infarct size in the pig. Padilla, F., Garcia-Dorado, D., Agulló, L., Inserte, J., Paniagua, A., Mirabet, S., Barrabés, J.A., Ruiz-Meana, M., Soler-Soler, J. Cardiovasc. Res. (2000) [Pubmed]
  28. Use of the RapID-ANA System to screen for enzyme activities that differ among species of bile-inhibited Bacteroides. Dellinger, C.A., Moore, L.V. J. Clin. Microbiol. (1986) [Pubmed]
  29. Scintigraphic detection of regional disruption of adrenergic neurons in the heart. Sisson, J.C., Lynch, J.J., Johnson, J., Jaques, S., Wu, D., Bolgos, G., Lucchesi, B.R., Wieland, D.M. Am. Heart J. (1988) [Pubmed]
  30. Reperfusion at reduced flow rates enhances postischemic contractile recovery of perfused heart. Takeo, S., Liu, J.X., Tanonaka, K., Nasa, Y., Yabe, K., Tanahashi, H., Sudo, H. Am. J. Physiol. (1995) [Pubmed]
  31. Cardioprotection is strain dependent in rat in response to whole body hyperthermia. Patel, H.H., Hsu, A., Gross, G.J. Am. J. Physiol. Heart Circ. Physiol. (2001) [Pubmed]
  32. Failure of N-2-mercaptopropionyl glycine to reduce myocardial infarction after 3 days of reperfusion in rabbits. Miki, T., Cohen, M.V., Downey, J.M. Basic Res. Cardiol. (1999) [Pubmed]
  33. Isoflurane and other commonly used anaesthetics do not protect the isolated buffer perfused mouse heart from ischemia-reperfusion injury. Galagudza, M., Vaage, J., Valen, G. Clin. Exp. Pharmacol. Physiol. (2006) [Pubmed]
  34. Effects of the KATP channel opener bimakalim on coronary blood flow, monophasic action potential duration, and infarct size in dogs. Yao, Z., Gross, G.J. Circulation (1994) [Pubmed]
  35. Short-term synchronized retroperfusion before reperfusion reduces infarct size after prolonged ischemia in dogs. Wakida, Y., Nordlander, R., Kobayashi, S., Kar, S., Haendchen, R., Corday, E. Circulation (1993) [Pubmed]
  36. Blood flow to infarct and surviving myocardium: implications regarding the action of verapamil on the acutely ischemic dog heart. Davenport, N., Goldstein, R.E., Bolli, R., Epstein, S.E. J. Am. Coll. Cardiol. (1984) [Pubmed]
  37. Effect of nitric oxide synthase inhibition on cerebral blood flow and injury volume during focal ischemia in cats. Nishikawa, T., Kirsch, J.R., Koehler, R.C., Bredt, D.S., Snyder, S.H., Traystman, R.J. Stroke (1993) [Pubmed]
  38. Intravenous metoprolol preceding thrombolysis in acute thrombotic myocardial infarction in the dog; effects on infarct size, myocardial blood flow, and left ventricular function. Zmudka, K., Dubiel, J., Vanhaecke, J., Flameng, W., De Geest, H. J. Cardiovasc. Pharmacol. (1994) [Pubmed]
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