Gene Review:
RNPEP - arginyl aminopeptidase (aminopeptidase B)
Homo sapiens
Synonyms:
AP-B, APB, Aminopeptidase B, Arginine aminopeptidase, Arginyl aminopeptidase
- Aminopeptidase B: a processing enzyme secreted and associated with the plasma membrane of rat pheochromocytoma (PC12) cells. Balogh, A., Cadel, S., Foulon, T., Picart, R., Der Garabedian, A., Rousselet, A., Tougard, C., Cohen, P. J. Cell. Sci. (1998)
- A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas. Henson, J.D., Hannay, J.A., McCarthy, S.W., Royds, J.A., Yeager, T.R., Robinson, R.A., Wharton, S.B., Jellinek, D.A., Arbuckle, S.M., Yoo, J., Robinson, B.G., Learoyd, D.L., Stalley, P.D., Bonar, S.F., Yu, D., Pollock, R.E., Reddel, R.R. Clin. Cancer Res. (2005)
- Long-term survival of patients with intermediate and high grade lymphoma treated with COMLA/ABP. Olopade, O.I., Larson, R.A., Mick, R., Watson, S.M., Hoffman, P.C., Ultmann, J.E., Golomb, H.M. Leukemia (1990)
- Effect of ubenimex on the proliferation and differentiation of U937 human histiocytic lymphoma cells. Murata, M., Kubota, Y., Tanaka, T., Iida-Tanaka, K., Takahara, J., Irino, S. Leukemia (1994)
- Properties of vertebrate glutamate receptors: calcium mobilization and desensitization. Zorumski, C.F., Thio, L.L. Prog. Neurobiol. (1992)
- Metabotropic glutamate receptor-mediated suppression of an inward rectifier current is linked via a cGMP cascade. Dixon, D.B., Copenhagen, D.R. J. Neurosci. (1997)
- APB (2-amino-4-phosphonobutyric acid) activates a chloride conductance in ganglion cells isolated from newt retina. Chiba, C., Saito, T. Neuroreport (1994)
- Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. Umezawa, H., Aoyagi, T., Suda, H., Hamada, M., Takeuchi, T. J. Antibiot. (1976)
- Expression and retinoid modulation of N-arginine dibasic convertase and an aminopeptidase-B in human neuroblastoma cell lines. Draoui, M., Bellincampi, L., Hospital, V., Cadel, S., Foulon, T., Prat, A., Barré, N., Reichert, U., Melino, G., Cohen, P. J. Neurooncol. (1997)
- Assignment of the aminopeptidase B gene (RNPEP) to human chromosome 1 band q32 by in situ hybridization. Aurich-Costa, J., Cadel, S., Gouzy, C., Foulon, T., Chérif, D., Cohen, P. Cytogenet. Cell Genet. (1997)
- Human aminopeptidase B (rnpep) on chromosome 1q32.2: complementary DNA, genomic structure and expression. Piesse, C., Tymms, M., Garrafa, E., Gouzy, C., Lacasa, M., Cadel, S., Cohen, P., Foulon, T. Gene (2002)
- Cloning and characterization of a bifunctional leukotriene A(4) hydrolase from Saccharomyces cerevisiae. Kull, F., Ohlson, E., Haeggström, J.Z. J. Biol. Chem. (1999)
- Two nuclear factor binding domains activate expression from the human amyloid beta-protein precursor promoter. Quitschke, W.W. J. Biol. Chem. (1994)
- Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases. Tanioka, T., Hattori, A., Masuda, S., Nomura, Y., Nakayama, H., Mizutani, S., Tsujimoto, M. J. Biol. Chem. (2003)
- Characterization and purification of T lymphocyte aminopeptidase B: a putative marker of T cell activation. Belhacene, N., Mari, B., Rossi, B., Auberger, P. Eur. J. Immunol. (1993)
- Facilitatory I wave interaction in proximal arm and lower limb muscle representations of the human motor cortex. Chen, R., Garg, R. J. Neurophysiol. (2000)
- Purification and characterization of a ubenimex (Bestatin)-sensitive aminopeptidase B-like enzyme from K562 human chronic myeloid leukemia cells. Yamada, M., Sukenaga, Y., Fujii, H., Abe, F., Takeuchi, T. FEBS Lett. (1994)
- Evidence of motor neuron involvement in chronic respiratory insufficiency. Valli, G., Barbieri, S., Sergi, P., Fayoumi, Z., Berardinelli, P. J. Neurol. Neurosurg. Psychiatr. (1984)
- Differential phospholipid binding by site 3 and site 4 toxins. Implications for structural variability between voltage-sensitive sodium channel domains. Smith, J.J., Alphy, S., Seibert, A.L., Blumenthal, K.M. J. Biol. Chem. (2005)
- Synthesis and structure-activity relationships of bestatin analogues, inhibitors of aminopeptidase B. Nishizawa, R., Saino, T., Takita, T., Suda, H., Aoyagi, T. J. Med. Chem. (1977)
- Synthesis of sulfur-containing analogues of bestatin. Inhibition of aminopeptidases by alpha-thiolbestatin analogues. Ocain, T.D., Rich, D.H. J. Med. Chem. (1988)
- Altered levels of acid, basic, and neutral peptidase activity and expression in human clear cell renal cell carcinoma. Varona, A., Blanco, L., López, J.I., Gil, J., Agirregoitia, E., Irazusta, J., Larrinaga, G. Am. J. Physiol. Renal Physiol. (2007)
- Brain aminopeptidases and hypertension. Banegas, I., Prieto, I., Vives, F., Alba, F., Gasparo, M., Segarra, A.B., Hermoso, F., Dur??n, R., Ram??rez, M. Journal of the renin-angiotensin-aldosterone system : JRAAS (2006)
- Types and localization of aminopeptidases in different human blood cells. Grdisa, M., Vitale, L. Int. J. Biochem. (1991)
- Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolase. Díaz-Perales, A., Quesada, V., Sánchez, L.M., Ugalde, A.P., Suárez, M.F., Fueyo, A., López-Otín, C. J. Biol. Chem. (2005)
- Differential effect of muscle vibration on intracortical inhibitory circuits in humans. Rosenkranz, K., Rothwell, J.C. J. Physiol. (Lond.) (2003)
- Automated rate nephelometric determination of apolipoproteins AI and B in human serum by consecutive addition of antibodies. Fotiou, F.K. Anal. Chem. (1992)
- Core substructure of the hemiellipsoidal phycobilisome from the red alga Porphyridium cruentum. Redecker, D., Wehrmeyer, W., Reuter, W. Eur. J. Cell Biol. (1993)