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Gene Review

Glo1  -  glyoxalase 1

Mus musculus

Synonyms: 0610009E22Rik, 1110008E19Rik, 2510049H23Rik, AW550643, Aldoketomutase, ...

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Disease relevance of Glo1


Psychiatry related information on Glo1


High impact information on Glo1


Biological context of Glo1


Anatomical context of Glo1


Associations of Glo1 with chemical compounds


Other interactions of Glo1


  1. Selective activation of apoptosis program by S-p-bromobenzylglutathione cyclopentyl diester in glyoxalase I-overexpressing human lung cancer cells. Sakamoto, H., Mashima, T., Sato, S., Hashimoto, Y., Yamori, T., Tsuruo, T. Clin. Cancer Res. (2001) [Pubmed]
  2. A glyoxalase I inhibitor of a new structural type produced by Streptomyces. Takeuchi, T., Chimura, H., Hamada, M., Umezawa, H., Yoshioka, O. J. Antibiot. (1975) [Pubmed]
  3. Erythrocyte glyoxalase activity in genetically obese (ob/ob) and streptozotocin diabetic mice. Atkins, T.W., Thornally, P.J. Diabetes Res. (1989) [Pubmed]
  4. Association analysis of the functional Ala111Glu polymorphism of the glyoxalase I gene in panic disorder. Politi, P., Minoretti, P., Falcone, C., Martinelli, V., Emanuele, E. Neurosci. Lett. (2006) [Pubmed]
  5. Deficiency in short-chain fatty acid beta-oxidation affects theta oscillations during sleep. Tafti, M., Petit, B., Chollet, D., Neidhart, E., de Bilbao, F., Kiss, J.Z., Wood, P.A., Franken, P. Nat. Genet. (2003) [Pubmed]
  6. Glyoxalase I polymorphism in the mouse: a new genetic marker linked to H-2. Meo, T., Douglas, T., Rijnbeek, A.M. Science (1977) [Pubmed]
  7. Assignment of a Mus musculus gene for triosephosphate isomerase to chromosome 6 and for glyoxalase-I to chromosome 17 using somatic cell hybrids. Minna, J.D., Bruns, G.A., Krinsky, A.H., Lalley, P.A., Francke, U., Gerald, P.S. Somatic Cell Genet. (1978) [Pubmed]
  8. Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r). Kumar, K.G., Poole, A.C., York, B., Volaufova, J., Zuberi, A., Richards, B.K. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2007) [Pubmed]
  9. Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE. Van Herreweghe, F., Mao, J., Chaplen, F.W., Grooten, J., Gevaert, K., Vandekerckhove, J., Vancompernolle, K. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  10. Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice. Hovatta, I., Tennant, R.S., Helton, R., Marr, R.A., Singer, O., Redwine, J.M., Ellison, J.A., Schadt, E.E., Verma, I.M., Lockhart, D.J., Barlow, C. Nature (2005) [Pubmed]
  11. Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety. Krömer, S.A., Kessler, M.S., Milfay, D., Birg, I.N., Bunck, M., Czibere, L., Panhuysen, M., Pütz, B., Deussing, J.M., Holsboer, F., Landgraf, R., Turck, C.W. J. Neurosci. (2005) [Pubmed]
  12. Glyoxalase activity in human tumour cell lines in vitro. Ayoub, F.M., Zaman, M.A., Thornalley, P.J., Masters, J.R. Biochem. Soc. Trans. (1993) [Pubmed]
  13. Alteration of glucose tolerance in mice fed low levels of aflatoxins and with depressed glyoxalase-I activity. Ankrah, N.A. Veterinary and human toxicology. (1995) [Pubmed]
  14. The location of the C3 and GLO (glyoxalase 1) loci of the IXth linkage group in mice. Rubinstein, P., Vienne, K., Hoecker, G.F. J. Immunol. (1979) [Pubmed]
  15. Deuterium isotope effects on the product partitioning of fluoromethylglyoxal by glyoxalase I. Proof of a proton transfer mechanism. Chari, R.V., Kozarich, J.W. J. Biol. Chem. (1981) [Pubmed]
  16. Glyoxalase I in detoxification: studies using a glyoxalase I transfectant cell line. Ranganathan, S., Walsh, E.S., Tew, K.D. Biochem. J. (1995) [Pubmed]
  17. Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity. Abordo, E.A., Minhas, H.S., Thornalley, P.J. Biochem. Pharmacol. (1999) [Pubmed]
  18. Inhibition of radiation-induced changes of glyoxalase I activity in mouse spleen and liver by phenothiazines. Luthra, R.S., Kale, R.K. Int. J. Radiat. Biol. (1995) [Pubmed]
  19. A glyoxalase-1 variant associated with the t-complex in house mice. Nadeau, J.H. Genetics (1986) [Pubmed]
  20. Orientation of loci in the major histocompatibility complex of the rat and its comparison to man and the mouse. Gill, T.J., Kunz, H.W., Schaid, D.J., VandeBerg, J.L., Stolc, V. J. Immunogenet. (1982) [Pubmed]
  21. Modulation of antioxidant potential in liver of mice by kernel oil of cashew nut (Anacardium occidentale) and its lack of tumour promoting ability in DMBA induced skin papillomagenesis. Singh, B., Kale, R.K., Rao, A.R. Indian J. Exp. Biol. (2004) [Pubmed]
  22. Modulation of glyoxalase, glutathione S-transferase and antioxidant enzymes in the liver, spleen and erythrocytes of mice by dietary administration of fenugreek seeds. Choudhary, D., Chandra, D., Choudhary, S., Kale, R.K. Food Chem. Toxicol. (2001) [Pubmed]
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