Gene Review:
Map3k1 - mitogen activated protein kinase kinase...
Rattus norvegicus
Synonyms:
MAPK/ERK kinase kinase 1, MEK kinase 1, MEKK 1, Mekk, Mekk1, ...
- Modulation of human cytomegalovirus immediate-early gene enhancer by mitogen-activated protein kinase kinase kinase-1. Sun, B., Harrowe, G., Reinhard, C., Yoshihara, C., Chu, K., Zhuo, S. J. Cell. Biochem. (2001)
- Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinases, and S6 kinase in cultured rat cardiac myocytes. Seko, Y., Tobe, K., Ueki, K., Kadowaki, T., Yazaki, Y. Circ. Res. (1996)
- MEKK4 mediates differentiation in response to retinoic acid via activation of c-Jun N-terminal kinase in rat embryonal carcinoma P19 cells. Kanungo, J., Potapova, I., Malbon, C.C., Wang, H. J. Biol. Chem. (2000)
- Differential regulation of Raf isozymes by growth versus differentiation inducing factors in PC12 pheochromocytoma cells. Wixler, V., Smola, U., Schuler, M., Rapp, U. FEBS Lett. (1996)
- Activation of TGF-beta1-TAK1-p38 MAPK pathway in spared cardiomyocytes is involved in left ventricular remodeling after myocardial infarction in rats. Matsumoto-Ida, M., Takimoto, Y., Aoyama, T., Akao, M., Takeda, T., Kita, T. Am. J. Physiol. Heart Circ. Physiol. (2006)
- Ras-dependent growth factor regulation of MEK kinase in PC12 cells. Lange-Carter, C.A., Johnson, G.L. Science (1994)
- Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation. Leppä, S., Saffrich, R., Ansorge, W., Bohmann, D. EMBO J. (1998)
- Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain. Xu, S., Robbins, D.J., Christerson, L.B., English, J.M., Vanderbilt, C.A., Cobb, M.H. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Ca2+- and Protein Kinase C-dependent Signaling Pathway for Nuclear Factor-{kappa}B Activation, Inducible Nitric-oxide Synthase Expression, and Tumor Necrosis Factor-{alpha} Production in Lipopolysaccharide-stimulated Rat Peritoneal Macrophages. Zhou, X., Yang, W., Li, J. J. Biol. Chem. (2006)
- Insulin activates a novel adipocyte mitogen-activated protein kinase kinase kinase that shows rapid phasic kinetics and is distinct from c-Raf. Haystead, C.M., Gregory, P., Shirazi, A., Fadden, P., Mosse, C., Dent, P., Haystead, T.A. J. Biol. Chem. (1994)
- Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion. Bogoyevitch, M.A., Gillespie-Brown, J., Ketterman, A.J., Fuller, S.J., Ben-Levy, R., Ashworth, A., Marshall, C.J., Sugden, P.H. Circ. Res. (1996)
- MEKK1 controls neurite regrowth after experimental injury by balancing ERK1/2 and JNK2 signaling. Waetzig, V., Herdegen, T. Mol. Cell. Neurosci. (2005)
- Disruption of Raf-1/heat shock protein 90 complex and Raf signaling by dexamethasone in mast cells. Cissel, D.S., Beaven, M.A. J. Biol. Chem. (2000)
- Differential binding of ceramide to MEKK1 in glomerular endothelial and mesangial cells. Huwiler, A., Xin, C., Brust, A.K., Briner, V.A., Pfeilschifter, J. Biochim. Biophys. Acta (2004)
- G alpha 13-mediated transformation and apoptosis are permissively dependent on basal ERK activity. Adarichev, V.A., Vaiskunaite, R., Niu, J., Balyasnikova, I.V., Voyno-Yasenetskaya, T.A. Am. J. Physiol., Cell Physiol. (2003)
- Presence and regulation of Raf-1-K (Kinase), MAPK-K, MAP-K, and S6-K in rat nephron segments. Terada, Y., Yamada, T., Takayama, M., Nonoguchi, H., Sasaki, S., Tomita, K., Marumo, F. J. Am. Soc. Nephrol. (1995)
- A novel lipopolysaccharide-modulated Jun binding repressor in intron 2 of CYP2E1. Tindberg, N., Bengtsson, I., Hu, Y. J. Neurochem. (2004)
- Retrograde axonal transport of signal transduction proteins in rat sciatic nerve. Johanson, S.O., Crouch, M.F., Hendry, I.A. Brain Res. (1995)
- Nerve growth factor stimulates a novel protein kinase in PC-12 cells that phosphorylates and activates mitogen-activated protein kinase kinase (MEK). Pang, L., Zheng, C.F., Guan, K.L., Saltiel, A.R. Biochem. J. (1995)
- PGE(2) stimulates VEGF expression in endothelial cells via ERK2/JNK1 signaling pathways. Pai, R., Szabo, I.L., Soreghan, B.A., Atay, S., Kawanaka, H., Tarnawski, A.S. Biochem. Biophys. Res. Commun. (2001)
- Statin inhibits interferon-gamma-induced expression of intercellular adhesion molecule-1 (ICAM-1) in vascular endothelial and smooth muscle cells. Chung, H.K., Lee, I.K., Kang, H., Suh, J.M., Kim, H., Park, K.C., Kim, D.W., Kim, Y.K., Ro, H.K., Shong, M. Exp. Mol. Med. (2002)
- The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras. Jaiswal, R.K., Moodie, S.A., Wolfman, A., Landreth, G.E. Mol. Cell. Biol. (1994)