Gene Review:
Prkcb - protein kinase C, beta
Rattus norvegicus
Synonyms:
PKC-B, PKC-beta, Pkcb, Prkcb1, Protein kinase C beta type
- Protein kinase CbetaII regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo. Liu, Y., Su, W., Thompson, E.A., Leitges, M., Murray, N.R., Fields, A.P. J. Biol. Chem. (2004)
- Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension. Kelly, D.J., Zhang, Y., Hepper, C., Gow, R.M., Jaworski, K., Kemp, B.E., Wilkinson-Berka, J.L., Gilbert, R.E. Diabetes (2003)
- Changes in protein kinase C isozymes in the rat hippocampus following transient hypoxia. Yamaoka, Y., Shimohama, S., Kimura, J., Fukunaga, R., Taniguchi, T. Neurosci. Lett. (1993)
- Alterations in brain protein kinase C after experimental brain injury. Padmaperuma, B., Mark, R., Dhillon, H.S., Mattson, M.P., Prasad, M.R. Brain Res. (1996)
- The occurrence of three isoenzymes of protein kinase C (alpha, beta and gamma) in retinas of different species. Osborne, N.N., Barnett, N.L., Morris, N.J., Huang, F.L. Brain Res. (1992)
- Changes in protein kinase C isoforms in association with vascular hyporeactivity in cirrhotic rat aortas. Tazi, K.A., Moreau, R., Heller, J., Poirel, O., Lebrec, D. Gastroenterology (2000)
- Regulation of angiotensin II-induced neuromodulation by MARCKS in brain neurons. Lu, D., Yang, H., Lenox, R.H., Raizada, M.K. J. Cell Biol. (1998)
- Tissue and cellular distribution of the extended family of protein kinase C isoenzymes. Wetsel, W.C., Khan, W.A., Merchenthaler, I., Rivera, H., Halpern, A.E., Phung, H.M., Negro-Vilar, A., Hannun, Y.A. J. Cell Biol. (1992)
- Protein kinases C-beta and C-epsilon link the mast cell high-affinity receptor for IgE to the expression of c-fos and c-jun. Razin, E., Szallasi, Z., Kazanietz, M.G., Blumberg, P.M., Rivera, J. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Tissue angiotensin II during progression or ventricular hypertrophy to heart failure in hypertensive rats; differential effects on PKC epsilon and PKC beta. Inagaki, K., Iwanaga, Y., Sarai, N., Onozawa, Y., Takenaka, H., Mochly-Rosen, D., Kihara, Y. J. Mol. Cell. Cardiol. (2002)
- Hypoxia induces activation of a N-methyl-D-aspartate glutamate receptor-protein kinase C pathway in the dorsocaudal brainstem of the conscious rat. Simakajornboon, N., Gozal, E., Gozal, Y.M., Gozal, D. Neurosci. Lett. (2000)
- Protein kinase C beta isoenzymes in diabetic kidneys and their relation to nephroprotective actions of the ACE inhibitor lisinopril. Pfaff, I.L., Vallon, V. Kidney Blood Press. Res. (2002)
- Ca2+- and Protein Kinase C-dependent Signaling Pathway for Nuclear Factor-{kappa}B Activation, Inducible Nitric-oxide Synthase Expression, and Tumor Necrosis Factor-{alpha} Production in Lipopolysaccharide-stimulated Rat Peritoneal Macrophages. Zhou, X., Yang, W., Li, J. J. Biol. Chem. (2006)
- Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway. Zhang, J., Anastasiadis, P.Z., Liu, Y., Thompson, E.A., Fields, A.P. J. Biol. Chem. (2004)
- Inhibition of PKCbeta improves glucocorticoid-induced insulin resistance in rat adipocytes. Kawai, Y., Ishizuka, T., Kajita, K., Miura, A., Ishizawa, M., Natsume, Y., Uno, Y., Morita, H., Yasuda, K. IUBMB Life (2002)
- Induction and subcellular localization of protein kinase C isozymes following renal ischemia. Padanilam, B.J. Kidney Int. (2001)
- Decreased expression of protein kinase-C alpha, beta, and epsilon in soleus muscle of Zucker obese (fa/fa) rats. Cooper, D.R., Watson, J.E., Dao, M.L. Endocrinology (1993)
- Regulation of amphetamine-stimulated dopamine efflux by protein kinase C beta. Johnson, L.A., Guptaroy, B., Lund, D., Shamban, S., Gnegy, M.E. J. Biol. Chem. (2005)
- Evidence for the involvement of a phospholipase C--protein kinase C signaling pathway in insulin stimulated glucose transport in skeletal muscle. Wright, D.C., Fick, C.A., Olesen, J.B., Craig, B.W. Life Sci. (2003)
- Characterization of site-specific mutants altered at protein kinase C beta 1 isozyme autophosphorylation sites. Zhang, J., Wang, L., Petrin, J., Bishop, W.R., Bond, R.W. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Differential effect of aging on protein kinase C activity in rat adipocytes and soleus muscle. Ishizuka, T., Yamamoto, M., Kajita, K., Yasuda, K., Miura, K., Hernandez, H., Farese, R.V. Metab. Clin. Exp. (1993)
- Corticotropin-releasing hormone activates protein kinase C in an isoenzyme-specific manner. Dermitzaki, E., Tsatsanis, C., Charalampopoulos, I., Androulidaki, A., Alexaki, V.I., Castanas, E., Gravanis, A., Margioris, A.N. Biochem. Biophys. Res. Commun. (2005)
- Different roles of protein kinase C-beta and -delta in arachidonic acid cascade, superoxide formation and phosphoinositide hydrolysis. Duyster, J., Schwende, H., Fitzke, E., Hidaka, H., Dieter, P. Biochem. J. (1993)
- Regulation of PKC alpha activity by C1-C2 domain interactions. Slater, S.J., Seiz, J.L., Cook, A.C., Buzas, C.J., Malinowski, S.A., Kershner, J.L., Stagliano, B.A., Stubbs, C.D. J. Biol. Chem. (2002)
- Parallel modulation of receptor for activated C kinase 1 and protein kinase C-alpha and beta isoforms in brains of morphine-treated rats. Escribá, P.V., García-Sevilla, J.A. Br. J. Pharmacol. (1999)
- Obligatory role of protein kinase Cbeta and MARCKS in vesicular trafficking in living neurons. Yang, H., Wang, X., Sumners, C., Raizada, M.K. Hypertension (2002)
- Role of protein kinase C on the expression of platelet-derived growth factor and endothelin-1 in the retina of diabetic rats and cultured retinal capillary pericytes. Yokota, T., Ma, R.C., Park, J.Y., Isshiki, K., Sotiropoulos, K.B., Rauniyar, R.K., Bornfeldt, K.E., King, G.L. Diabetes (2003)
- High glucose augments the angiotensin II-induced activation of JAK2 in vascular smooth muscle cells via the polyol pathway. Shaw, S., Wang, X., Redd, H., Alexander, G.D., Isales, C.M., Marrero, M.B. J. Biol. Chem. (2003)
- Involvement of PKC-beta in PTH, TNF-alpha, and IL-1 beta effects on IL-6 promoter in osteoblastic cells and on PTH-stimulated bone resorption. Radeff, J.M., Nagy, Z., Stern, P.H. Exp. Cell Res. (2001)
- Normalization of diacylglycerol-protein kinase C activation by vitamin E in aorta of diabetic rats and cultured rat smooth muscle cells exposed to elevated glucose levels. Kunisaki, M., Bursell, S.E., Umeda, F., Nawata, H., King, G.L. Diabetes (1994)
- Different isozymes of protein kinase C mediate feedback inhibition of phospholipase C and stimulatory signals for exocytosis in rat RBL-2H3 cells. Ozawa, K., Yamada, K., Kazanietz, M.G., Blumberg, P.M., Beaven, M.A. J. Biol. Chem. (1993)