Gene Review:
Grin1 - glutamate receptor, ionotropic, NMDA1...
Mus musculus
Synonyms:
GluN1, GluRdelta1, GluRzeta1, Glurz1, Glutamate receptor ionotropic, NMDA 1, ...
Bigini,
Gardoni,
Barbera,
Cagnotto,
Fumagalli,
Longhi,
Corsi,
Di Luca,
Mennini,
Tan-No,
Esashi,
Nakagawasai,
Niijima,
Sakurada,
Sakurada,
Bakalkin,
Terenius,
Tadano,
Offenhäuser,
Castelletti,
Mapelli,
Soppo,
Regondi,
Rossi,
D'Angelo,
Frassoni,
Amadeo,
Tocchetti,
Pozzi,
Disanza,
Guarnieri,
Betsholtz,
Scita,
Heberlein,
Di Fiore,
Kew,
Koester,
Moreau,
Jenck,
Ouagazzal,
Mutel,
Richards,
Trube,
Fischer,
Montkowski,
Hundt,
Reinscheid,
Pauly-Evers,
Kemp,
Bluethmann,
Metzger,
Pieri,
Eisel,
Nada,
Shima,
Yanai,
Husi,
Grant,
Okada,
Akiyama,
Vadakkan,
Wang,
Ko,
Zastepa,
Petrovic,
Sluka,
Zhuo,
El-Etr,
Akwa,
Baulieu,
Schumacher,
- Attenuation of focal ischemic brain injury in mice deficient in the epsilon1 (NR2A) subunit of NMDA receptor. Morikawa, E., Mori, H., Kiyama, Y., Mishina, M., Asano, T., Kirino, T. J. Neurosci. (1998)
- Dopamine D1-dependent trafficking of striatal N-methyl-D-aspartate glutamate receptors requires Fyn protein tyrosine kinase but not DARPP-32. Dunah, A.W., Sirianni, A.C., Fienberg, A.A., Bastia, E., Schwarzschild, M.A., Standaert, D.G. Mol. Pharmacol. (2004)
- Expression of AMPA and NMDA receptor subunits in the cervical spinal cord of wobbler mice. Bigini, P., Gardoni, F., Barbera, S., Cagnotto, A., Fumagalli, E., Longhi, A., Corsi, M.M., Di Luca, M., Mennini, T. BMC neuroscience (2006)
- Translational regulation of the N-methyl-D-aspartate receptor subunit NR1. Vazhappilly, R., Sucher, N.J. Neurosignals (2004)
- Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs. Meguro, H., Mori, H., Araki, K., Kushiya, E., Kutsuwada, T., Yamazaki, M., Kumanishi, T., Arakawa, M., Sakimura, K., Mishina, M. Nature (1992)
- Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition. Lu, H.C., Gonzalez, E., Crair, M.C. Neuron (2001)
- Conantokins and variants derived from cone snail venom inhibit naloxone-induced withdrawal jumping in morphine-dependent mice. Wei, J., Dong, M., Xiao, C., Jiang, F., Castellino, F.J., Prorok, M., Dai, Q. Neurosci. Lett. (2006)
- Genetic reduction of chronic muscle pain in mice lacking calcium/calmodulin-stimulated adenylyl cyclases. Vadakkan, K.I., Wang, H., Ko, S.W., Zastepa, E., Petrovic, M.J., Sluka, K.A., Zhuo, M. Molecular pain [electronic resource] (2006)
- Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Mohn, A.R., Gainetdinov, R.R., Caron, M.G., Koller, B.H. Cell (1999)
- Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice. Rampon, C., Tang, Y.P., Goodhouse, J., Shimizu, E., Kyin, M., Tsien, J.Z. Nat. Neurosci. (2000)
- Increased ethanol resistance and consumption in eps8 knockout mice correlates with altered actin dynamics. Offenh??user, N., Castelletti, D., Mapelli, L., Soppo, B.E., Regondi, M.C., Rossi, P., D'Angelo, E., Frassoni, C., Amadeo, A., Tocchetti, A., Pozzi, B., Disanza, A., Guarnieri, D., Betsholtz, C., Scita, G., Heberlein, U., Di Fiore, P.P. Cell (2006)
- Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination. Watanabe, D., Inokawa, H., Hashimoto, K., Suzuki, N., Kano, M., Shigemoto, R., Hirano, T., Toyama, K., Kaneko, S., Yokoi, M., Moriyoshi, K., Suzuki, M., Kobayashi, K., Nagatsu, T., Kreitman, R.J., Pastan, I., Nakanishi, S. Cell (1998)
- The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Tsien, J.Z., Huerta, P.T., Tonegawa, S. Cell (1996)
- Distribution of alpha-amino-3-hydroxy-5-methyl-4 isoazolepropionic acid and N-methyl-D-aspartate receptor subunits in the vestibular and spiral ganglia of the mouse during early development. Puyal, J., Sage, C., Demêmes, D., Dechesne, C.J. Brain Res. Dev. Brain Res. (2002)
- Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Sattler, R., Xiong, Z., Lu, W.Y., Hafner, M., MacDonald, J.F., Tymianski, M. Science (1999)
- Neuropathic sensitization of behavioral reflexes and spinal NMDA receptor/CaM kinase II interactions are disrupted in PSD-95 mutant mice. Garry, E.M., Moss, A., Delaney, A., O'Neill, F., Blakemore, J., Bowen, J., Husi, H., Mitchell, R., Grant, S.G., Fleetwood-Walker, S.M. Curr. Biol. (2003)
- Stimulation of adenosine A2A receptors elicits zif/268 and NMDA epsilon2 subunit mRNA expression in cortex and striatum of the "weaver" mutant mouse, a genetic model of nigrostriatal dopamine deficiency. Ekonomou, A., Poulou, P.D., Matsokis, N., Angelatou, F. Neuroscience (2004)
- NMDA and AMPA glutamate receptor subtypes in the thoracic spinal cord in lean and obese-diabetic ob/ob mice. Li, N., Young, M.M., Bailey, C.J., Smith, M.E. Brain Res. (1999)
- Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site. Kew, J.N., Koester, A., Moreau, J.L., Jenck, F., Ouagazzal, A.M., Mutel, V., Richards, J.G., Trube, G., Fischer, G., Montkowski, A., Hundt, W., Reinscheid, R.K., Pauly-Evers, M., Kemp, J.A., Bluethmann, H. J. Neurosci. (2000)
- Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit. Sakimura, K., Kutsuwada, T., Ito, I., Manabe, T., Takayama, C., Kushiya, E., Yagi, T., Aizawa, S., Inoue, Y., Sugiyama, H. Nature (1995)
- NMDA receptors regulate developmental gap junction uncoupling via CREB signaling. Arumugam, H., Liu, X., Colombo, P.J., Corriveau, R.A., Belousov, A.B. Nat. Neurosci. (2005)
- Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. Forrest, D., Yuzaki, M., Soares, H.D., Ng, L., Luk, D.C., Sheng, M., Stewart, C.L., Morgan, J.I., Connor, J.A., Curran, T. Neuron (1994)
- Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice. Fukaya, M., Kato, A., Lovett, C., Tonegawa, S., Watanabe, M. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Biochemical evidence for the existence of a pool of unassembled C2 exon-containing NR1 subunits of the mammalian forebrain NMDA receptor. Chazot, P.L., Stephenson, F.A. J. Neurochem. (1997)
- Reduced NMDA receptor tyrosine phosphorylation in PTPalpha-deficient mouse synaptosomes is accompanied by inhibition of four src family kinases and Pyk2: an upstream role for PTPalpha in NMDA receptor regulation. Le, H.T., Maksumova, L., Wang, J., Pallen, C.J. J. Neurochem. (2006)
- Identification of PSD-93 as a substrate for the Src family tyrosine kinase Fyn. Nada, S., Shima, T., Yanai, H., Husi, H., Grant, S.G., Okada, M., Akiyama, T. J. Biol. Chem. (2003)
- The neuroactive steroid pregnenolone sulfate stimulates the release of gonadotropin-releasing hormone from GT1-7 hypothalamic neurons, through N-methyl-D-aspartate receptors. El-Etr, M., Akwa, Y., Baulieu, E.E., Schumacher, M. Endocrinology (2006)
- Co-induction of growth-associated protein GAP-43 and neuronal nitric oxide synthase in the cochlear nucleus following cochleotomy. Chen, T.J., Huang, C.W., Wang, D.C., Chen, S.S. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (2004)
- Phosphorylation-dependent regulation of N-methyl-D-aspartate receptors by calmodulin. Hisatsune, C., Umemori, H., Inoue, T., Michikawa, T., Kohda, K., Mikoshiba, K., Yamamoto, T. J. Biol. Chem. (1997)
- Nociceptive behavior induced by poly-L-lysine and other basic compounds involves the spinal NMDA receptors. Tan-No, K., Esashi, A., Nakagawasai, O., Niijima, F., Sakurada, C., Sakurada, T., Bakalkin, G., Terenius, L., Tadano, T. Brain Res. (2004)
- Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors. Vanhoose, A.M., Clements, J.M., Winder, D.G. J. Neurosci. (2006)
- Analysis of NMDA receptor mediated synaptic plasticity using gene targeting: roles of Fyn and FAK non-receptor tyrosine kinases. Grant, S.G. J. Physiol. Paris (1996)
- NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin. Matsumoto-Miyai, K., Ninomiya, A., Yamasaki, H., Tamura, H., Nakamura, Y., Shiosaka, S. J. Neurosci. (2003)
- Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons. Xu, Y., Zhang, B., Hua, Z., Johns, R.A., Bredt, D.S., Tao, Y.X. Exp. Neurol. (2004)
- Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-d-aspartate receptors. Torres-Peraza, J., Pezzi, S., Canals, J.M., Gavald??, N., Garc??a-Mart??nez, J.M., P??rez-Navarro, E., Alberch, J. Neuroscience (2007)
- NMDA-receptor proteins are upregulated in the hippocampus of postnatal heterozygous reeler mice. Isosaka, T., Hattori, K., Yagi, T. Brain Res. (2006)
- Reelin, very-low-density lipoprotein receptor, and apolipoprotein E receptor 2 control somatic NMDA receptor composition during hippocampal maturation in vitro. Sinagra, M., Verrier, D., Frankova, D., Korwek, K.M., Blahos, J., Weeber, E.J., Manzoni, O.J., Chavis, P. J. Neurosci. (2005)
- Lack of NMDA receptor subunit exchange alters Purkinje cell dendritic morphology in cerebellar slice cultures. Metzger, F., Pieri, I., Eisel, U.L. Brain Res. Dev. Brain Res. (2005)
- Effect of transgenic overexpression of NR2B on NMDA receptor function and synaptic plasticity in visual cortex. Philpot, B.D., Weisberg, M.P., Ramos, M.S., Sawtell, N.B., Tang, Y.P., Tsien, J.Z., Bear, M.F. Neuropharmacology (2001)
- Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein. Tao, Y.X., Rumbaugh, G., Wang, G.D., Petralia, R.S., Zhao, C., Kauer, F.W., Tao, F., Zhuo, M., Wenthold, R.J., Raja, S.N., Huganir, R.L., Bredt, D.S., Johns, R.A. J. Neurosci. (2003)
- NR2B and NR2D subunits coassemble in cerebellar Golgi cells to form a distinct NMDA receptor subtype restricted to extrasynaptic sites. Brickley, S.G., Misra, C., Mok, M.H., Mishina, M., Cull-Candy, S.G. J. Neurosci. (2003)
- Synthesis, binding affinity at glutamic acid receptors, neuroprotective effects, and molecular modeling investigation of novel dihydroisoxazole amino acids. Conti, P., De Amici, M., Grazioso, G., Roda, G., Pinto, A., Hansen, K.B., Nielsen, B., Madsen, U., Bräuner-Osborne, H., Egebjerg, J., Vestri, V., Pellegrini-Giampietro, D.E., Sibille, P., Acher, F.C., De Micheli, C. J. Med. Chem. (2005)
- NMDA receptor subunits GluRepsilon1, GluRepsilon3 and GluRzeta1 are enriched at the mossy fibre-granule cell synapse in the adult mouse cerebellum. Yamada, K., Fukaya, M., Shimizu, H., Sakimura, K., Watanabe, M. Eur. J. Neurosci. (2001)
- NMDA receptor subunit mRNA and protein expression in ethanol-withdrawal seizure-prone and -resistant mice. Mason, J.N., Eshleman, A.J., Belknap, J.K., Crabbe, J.C., Loftis, J.M., Macey, T.A., Janowsky, A. Alcohol. Clin. Exp. Res. (2001)