Gene Review:
Lpin1 - lipin 1
Mus musculus
Synonyms:
4631420P06, Fatty liver dystrophy protein, Fld, Kiaa0188, Lipin-1, ...
- Lipin expression preceding peroxisome proliferator-activated receptor-gamma is critical for adipogenesis in vivo and in vitro. Phan, J., Péterfy, M., Reue, K. J. Biol. Chem. (2004)
- Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin. Péterfy, M., Phan, J., Xu, P., Reue, K. Nat. Genet. (2001)
- Characterization of the peripheral neuropathy in neonatal and adult mice that are homozygous for the fatty liver dystrophy (fld) mutation. Langner, C.A., Birkenmeier, E.H., Roth, K.A., Bronson, R.T., Gordon, J.I. J. Biol. Chem. (1991)
- Local regulation of fat metabolism in peripheral nerves. Verheijen, M.H., Chrast, R., Burrola, P., Lemke, G. Genes Dev. (2003)
- Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin. Huffman, T.A., Mothe-Satney, I., Lawrence, J.C. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic Acid phosphatase, lipin 1. Harris, T.E., Huffman, T.A., Chi, A., Shabanowitz, J., Hunt, D.F., Kumar, A., Lawrence, J.C. J. Biol. Chem. (2007)
- Genetic, physical, and transcript map of the fld region on mouse chromosome 12. Péterfy, M., Phan, J., Oswell, G.M., Xu, P., Reue, K. Genomics (1999)
- The fatty liver dystrophy (fld) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities. Langner, C.A., Birkenmeier, E.H., Ben-Zeev, O., Schotz, M.C., Sweet, H.O., Davisson, M.T., Gordon, J.I. J. Biol. Chem. (1989)
- The fatty liver dystrophy mutant mouse: microvesicular steatosis associated with altered expression levels of peroxisome proliferator-regulated proteins. Rehnmark, S., Giometti, C.S., Slavin, B.G., Doolittle, M.H., Reue, K. J. Lipid Res. (1998)
- Naturally occurring mutations in mice affecting lipid transport and metabolism. Reue, K., Doolittle, M.H. J. Lipid Res. (1996)
- The fat and thin of lipin. Reitman, M.L. Cell metabolism. (2005)
- Trans-10, cis-12 conjugated linoleic acid causes inflammation and delipidation of white adipose tissue in mice: a microarray and histological analysis. LaRosa, P.C., Miner, J., Xia, Y., Zhou, Y., Kachman, S., Fromm, M.E. Physiol. Genomics (2006)
- Genome-wide Expression Analysis Reveals 100 Adrenal Gland-dependent Circadian Genes in the Mouse Liver. Oishi, K., Amagai, N., Shirai, H., Kadota, K., Ohkura, N., Ishida, N. DNA Res. (2005)
- Lipin deficiency impairs diurnal metabolic fuel switching. Xu, J., Lee, W.N., Phan, J., Saad, M.F., Reue, K., Kurland, I.J. Diabetes (2006)
- Lipin, a lipodystrophy and obesity gene. Phan, J., Reue, K. Cell metabolism. (2005)
- The fld mutation maps near to but distinct from the Apob locus on mouse chromosome 12. Rowe, L.B., Sweet, H.O., Gordon, J.I., Birkenmeier, E.H. Mamm. Genome (1996)
- Acads gene deletion in BALB/cByJ mouse strain occurred after 1981 and is not present in BALB/cByJ-fld mutant mice. Reue, K., Cohen, R.D. Mamm. Genome (1996)
- Lipin Expression Is Attenuated in Adipose Tissue of Insulin-Resistant Human Subjects and Increases With Peroxisome Proliferator-Activated Receptor {gamma} Activation. Yao-Borengasser, A., Rasouli, N., Varma, V., Miles, L.M., Phanavanh, B., Starks, T.N., Phan, J., Spencer, H.J., McGehee, R.E., Reue, K., Kern, P.A. Diabetes (2006)