Gene Review:
CSNK2A2 - casein kinase 2, alpha prime polypeptide
Homo sapiens
Synonyms:
CK II alpha', CK2A2, CSNK2A1, Casein kinase II subunit alpha'
- Phosphorylation of serine 208 in the human vitamin D receptor. The predominant amino acid phosphorylated by casein kinase II, in vitro, and identification as a significant phosphorylation site in intact cells. Jurutka, P.W., Hsieh, J.C., MacDonald, P.N., Terpening, C.M., Haussler, C.A., Haussler, M.R., Whitfield, G.K. J. Biol. Chem. (1993)
- Biochemical characterization of HIV-1 Rev as a potent activator of casein kinase II in vitro. Ohtsuki, K., Maekawa, T., Harada, S., Karino, A., Morikawa, Y., Ito, M. FEBS Lett. (1998)
- Casein kinase II is associated with neurofibrillary tangles but is not an intrinsic component of paired helical filaments. Baum, L., Masliah, E., Iimoto, D.S., Hansen, L.A., Halliday, W.C., Saitoh, T. Brain Res. (1992)
- Enhanced casein kinase II activity in metastatic melanoma. Mitev, V., Miteva, L., Botev, I., Houdebine, L.M. J. Dermatol. Sci. (1994)
- Casein kinase II alteration precedes tau accumulation in tangle formation. Masliah, E., Iimoto, D.S., Mallory, M., Albright, T., Hansen, L., Saitoh, T. Am. J. Pathol. (1992)
- Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail. Jones, B.G., Thomas, L., Molloy, S.S., Thulin, C.D., Fry, M.D., Walsh, K.A., Thomas, G. EMBO J. (1995)
- Casein kinase II is a predominantly nuclear enzyme. Krek, W., Maridor, G., Nigg, E.A. J. Cell Biol. (1992)
- The rate of nuclear cytoplasmic protein transport is determined by the casein kinase II site flanking the nuclear localization sequence of the SV40 T-antigen. Rihs, H.P., Jans, D.A., Fan, H., Peters, R. EMBO J. (1991)
- The catalytic subunit alpha' gene of human protein kinase CK2 (CSNK2A2): genomic organization, promoter identification and determination of Ets1 as a key regulator. Ackermann, K., Neidhart, T., Gerber, J., Waxmann, A., Pyerin, W. Mol. Cell. Biochem. (2005)
- Phosphohexose isomerase/autocrine motility factor/neuroleukin/maturation factor is a multifunctional phosphoprotein. Haga, A., Niinaka, Y., Raz, A. Biochim. Biophys. Acta (2000)
- s-Myc acts as a transcriptional activator and its sequence-specific DNA binding is required for induction of programmed cell death in glioma cells. Kitanaka, C., Sugiyama, A., Kanazu, S., Miyagi, Y., Mishima, K., Asai, A., Kuchino, Y. Cell Death Differ. (1995)
- Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit. Yang-Feng, T.L., Zheng, K., Kopatz, I., Naiman, T., Canaani, D. Nucleic Acids Res. (1991)
- A majority of casein kinase II alpha subunit is tightly bound to intranuclear components but not to the beta subunit. Stigare, J., Buddelmeijer, N., Pigon, A., Egyhazi, E. Mol. Cell. Biochem. (1993)
- Serum-stimulated cell growth causes oscillations in casein kinase II activity. Carroll, D., Marshak, D.R. J. Biol. Chem. (1989)
- DNA-binding sperm proteins with oligo-arginine clusters function as potent activators for egg CK-II. Ohtsuki, K., Nishikawa, Y., Saito, H., Munakata, H., Kato, T. FEBS Lett. (1996)
- Casein kinase II activities related to hyperphosphorylation of human papillomavirus type 16-E7 oncoprotein in epidermal keratinocytes. Hashida, T., Yasumoto, S. Biochem. Biophys. Res. Commun. (1990)
- Aberrant casein kinase II in Alzheimer's disease. Iimoto, D.S., Masliah, E., DeTeresa, R., Terry, R.D., Saitoh, T. Brain Res. (1990)
- Human vitamin D receptor phosphorylation by casein kinase II at Ser-208 potentiates transcriptional activation. Jurutka, P.W., Hsieh, J.C., Nakajima, S., Haussler, C.A., Whitfield, G.K., Haussler, M.R. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Identification of glycyrrhizin-binding protein kinase as casein kinase II and characterization of its associated phosphate acceptors in mouse liver. Harada, S., Karino, A., Shimoyama, Y., Shamsa, F., Ohtsuki, K. Biochem. Biophys. Res. Commun. (1996)
- Distribution of MAP kinase, S6 kinase, and casein kinase II in rat tissues: activation by insulin in spleen. Hei, Y.J., Chen, X., Diamond, J., McNeill, J.H. Biochem. Cell Biol. (1994)