Disease relevance of Impact

• Inhibitory Impact of Bifidobacteria on the Transfer of {beta}-Lactam Resistance among Enterobacteriaceae in the Gnotobiotic Mouse Digestive Tract [1].
• Significance and Impact of the Study: The ability of heat-killed Mix-LAB to prevent bacterial infection in mice was found to be more significant than that of viable monostrain [2].
• Significance and Impact of the Study: This study demonstrated the antibacterial activity of PTC against E. coli and its ability to maintain healthy intestinal microbial community in mice even after they were infected with E. coli [3].
• Optimisation of secretion of recombinant HBsAg virus-like particles: Impact on the development of HIV-1/HBV bivalent vaccines [4].
• Delayed cutaneous hypersensitivity was slightly higher in the Impact group but this was not statistically significant [5].

Psychiatry related information on Impact

• The international society for developmental psychobiology annual meeting symposium: Impact of early life experiences on brain and behavioral development [6].

High impact information on Impact

• Is mom too sensitive? Impact of maternal stress during gestation [7].
• Three spontaneous H-2Db mutants are generated by genetic micro-recombination (gene conversion) events. Impact on the H-2-restricted immune responsiveness [8].
• Effects of Palmitate on Ca2+ Handling in Adult Control and ob/ob Cardiomyocytes: Impact of Mitochondrial Reactive Oxygen Species [9].
• Immunoproteasome Subunit Deficiencies Impact Differentially on Two Immunodominant Influenza Virus-Specific CD8+ T Cell Responses [10].
• Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption [11].

Biological context of Impact

• Mutant monoclonal antibodies with select alteration in complement activation ability. Impact on immune complex functions in vivo [12].
• Liquid Impact was associated with cecal bacterial overgrowth but had no effect on the incidence of bacterial translocation [13].
• Digestion, Absorption and Tissue Distribution of Ovalbumin and Palmitoyl-ovalbumin: Impact on Immune Responses Triggered by Orally Administered Antigens [14].
• This article is based on the closing address given by Dr. Mitchell Spellman on behalf of Harvard Medical International at the third biennial Asan Medical Center-Harvard Medical International Symposium titled "Genetics and Proteomics: Impact on Medicine and Health" that took place at the Asan Medical Center in Seoul, Korea, July 3-4, 2001 [15].
• Indeed, comparative analysis of a species-specific imprinted gene Impact using a broader range of mammals led us to propose an alternative dosage control hypothesis for the evolution of genomic imprinting [16].

Anatomical context of Impact

• Interleukin-1{alpha}-Induced Chemokines in Mouse Granulosa Cells: Impact on Keratinocyte Chemoattractant Chemokine, a CXC Subfamily [17].
• Quantitative Assessment of Human T Lymphocytes in RAG2(-/-)gammac(-/-) Mice: The Impact of Ex Vivo Manipulation on In Vivo Functionality [18].
• A comparison of factors associated with collagen metabolism in different skeletal muscles from dystrophic (mdx) mice: Impact of pirfenidone [19].
• Functional importance of CD4+ and CD8+ cells in cytotoxic lymphocytes activity and associated gene expression. Impact on the age-related decline in lytic activity [20].
• Natural killer cell activity was significantly higher in the Impact group compared with the other two feeding regimens [5].

Associations of Impact with chemical compounds

• Because all parenteral and most enteral nutrient solutions are nucleotide free, clinical studies were undertaken comparing a new nucleotide containing diet (Impact) to a standard high protein enteral feeding [21].
• Mortality was significantly less in animals fed Impact, a formula enriched with arginine, RNA and selected fatty acids [5].
• Effect of indomethacin and Impact liquid diet administration on inflammatory mediator production by murine splenocytes after burn injury [22].

Analytical, diagnostic and therapeutic context of Impact

• In addition, infectious complications and length of hospital stay were reduced in postoperative cancer patients fed Impact compared with a control group [21].
• Secondary outcome measures were the rate of deterioration of function assessed by the modified Norris limb and bulbar scales, manual muscle testing (BMRC), spasticity scale, ventilatory function and the Sickness Impact Profile (SIP ALS/19) [23].

References