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Chemical Compound Review

Singlet oxygen     oxygen

Synonyms: Monooxygen, Photooxygen, oxidanediyl, Oxygen atom, Atomic oxygen, ...
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Disease relevance of oxygen


Psychiatry related information on oxygen


High impact information on oxygen


Chemical compound and disease context of oxygen


Biological context of oxygen


Anatomical context of oxygen


Associations of oxygen with other chemical compounds


Gene context of oxygen


Analytical, diagnostic and therapeutic context of oxygen


  1. Selection of patients with chronic obstructive pulmonary disease for long-term oxygen therapy. Timms, R.M., Kvale, P.A., Anthonisen, N.R., Boylen, C.T., Cugell, D.W., Petty, T.L., Williams, G.W. JAMA (1981) [Pubmed]
  2. Hypoxia Enhances S-Nitrosylation-Mediated NMDA Receptor Inhibition via a Thiol Oxygen Sensor Motif. Takahashi, H., Shin, Y., Cho, S.J., Zago, W.M., Nakamura, T., Gu, Z., Ma, Y., Furukawa, H., Liddington, R., Zhang, D., Tong, G., Chen, H.S., Lipton, S.A. Neuron (2007) [Pubmed]
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  8. Circulating xanthine oxidase and neutrophil activation during human liver transplantation. Pesonen, E.J., Linder, N., Raivio, K.O., Sarnesto, A., Lapatto, R., Höckerstedt, K., Mäkisalo, H., Andersson, S. Gastroenterology (1998) [Pubmed]
  9. Tumor Necrosis Factor-{alpha} Increases Reactive Oxygen Species by Inducing Spermine Oxidase in Human Lung Epithelial Cells: A Potential Mechanism for Inflammation-Induced Carcinogenesis. Babbar, N., Casero, R.A. Cancer Res. (2006) [Pubmed]
  10. A Novel BH3 Mimetic Reveals a Mitogen-Activated Protein Kinase-Dependent Mechanism of Melanoma Cell Death Controlled by p53 and Reactive Oxygen Species. Verhaegen, M., Bauer, J.A., Mart??n de la Vega, C., Wang, G., Wolter, K.G., Brenner, J.C., Nikolovska-Coleska, Z., Bengtson, A., Nair, R., Elder, J.T., Van Brocklin, M., Carey, T.E., Bradford, C.R., Wang, S., Soengas, M.S. Cancer Res. (2006) [Pubmed]
  11. Proceedings of the Oxygen Homeostasis/Hypoxia Meeting. Kaufman, B., Scharf, O., Arbeit, J., Ashcroft, M., Brown, J.M., Bruick, R.K., Chapman, J.D., Evans, S.M., Giaccia, A.J., Harris, A.L., Huang, E., Johnson, R., Kaelin, W., Koch, C.J., Maxwell, P., Mitchell, J., Neckers, L., Powis, G., Rajendran, J., Semenza, G.L., Simons, J., Storkebaum, E., Welch, M.J., Whitelaw, M., Melillo, G., Ivy, S.P. Cancer Res. (2004) [Pubmed]
  12. Crystal Structure of 3-Hydroxybenzoate Hydroxylase from Comamonas testosteroni Has a Large Tunnel for Substrate and Oxygen Access to the Active Site. Hiromoto, T., Fujiwara, S., Hosokawa, K., Yamaguchi, H. J. Mol. Biol. (2006) [Pubmed]
  13. A Mycobacterium marinum mel2 Mutant Is Defective for Growth in Macrophages That Produce Reactive Oxygen and Reactive Nitrogen Species. Subbian, S., Mehta, P.K., Cirillo, S.L., Bermudez, L.E., Cirillo, J.D. Infect. Immun. (2007) [Pubmed]
  14. Blue news: NTP binding properties of the blue-light sensitive YtvA protein from Bacillus subtilis. Buttani, V., Losi, A., Polverini, E., Gärtner, W. FEBS Lett. (2006) [Pubmed]
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  16. Differential sensitivity of tumor cells to externally generated hydrogen peroxide. Role of glutathione and related enzymes. Bozzi, A., Mavelli, I., Mondovì, B., Strom, R., Rotilio, G. Cancer Biochem. Biophys. (1979) [Pubmed]
  17. Kinetics of ATP and inorganic phosphate release during hydrolysis of ATP by rabbit skeletal actomyosin subfragment 1. Oxygen exchange between water and ATP or phosphate. Bowater, R., Zimmerman, R.W., Webb, M.R. J. Biol. Chem. (1990) [Pubmed]
  18. Menadione-induced Reactive Oxygen Species Generation via Redox Cycling Promotes Apoptosis of Murine Pancreatic Acinar Cells. Criddle, D.N., Gillies, S., Baumgartner-Wilson, H.K., Jaffar, M., Chinje, E.C., Passmore, S., Chvanov, M., Barrow, S., Gerasimenko, O.V., Tepikin, A.V., Sutton, R., Petersen, O.H. J. Biol. Chem. (2006) [Pubmed]
  19. ATP Activates a Reactive Oxygen Species-dependent Oxidative Stress Response and Secretion of Proinflammatory Cytokines in Macrophages. Cruz, C.M., Rinna, A., Forman, H.J., Ventura, A.L., Persechini, P.M., Ojcius, D.M. J. Biol. Chem. (2007) [Pubmed]
  20. Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes. Martin, G., Andriamanalijaona, R., Grässel, S., Dreier, R., Mathy-Hartert, M., Bogdanowicz, P., Boumédiene, K., Henrotin, Y., Bruckner, P., Pujol, J.P. Arthritis Rheum. (2004) [Pubmed]
  21. In the Absence of Reactive Oxygen Species, T Cells Default to a Th1 Phenotype and Mediate Protection against Pulmonary Cryptococcus neoformans Infection. Snelgrove, R.J., Edwards, L., Williams, A.E., Rae, A.J., Hussell, T. J. Immunol. (2006) [Pubmed]
  22. Measurement of the reversibility of ATP binding to myosin in calcium-activated skinned fibers from rabbit skeletal muscle. Oxygen exchange between water and ATP released to the solution. Bowater, R., Webb, M.R., Ferenczi, M.A. J. Biol. Chem. (1989) [Pubmed]
  23. Factors influencing the oxygen concentration gradient from the synovial surface of articular cartilage to the cartilage-bone interface: a modeling study. Zhou, S., Cui, Z., Urban, J.P. Arthritis Rheum. (2004) [Pubmed]
  24. Influence of hypoxia and reoxygenation on cytokine-induced production of proinflammatory mediators in articular cartilage. Cernanec, J., Guilak, F., Weinberg, J.B., Pisetsky, D.S., Fermor, B. Arthritis Rheum. (2002) [Pubmed]
  25. Effect of gamma radiation on resting B lymphocytes. I. Oxygen-dependent damage to the plasma membrane results in increased permeability and cell enlargement. Ashwell, J.D., Schwartz, R.H., Mitchell, J.B., Russo, A. J. Immunol. (1986) [Pubmed]
  26. A novel site of erythropoietin production. Oxygen-dependent production in cultured rat astrocytes. Masuda, S., Okano, M., Yamagishi, K., Nagao, M., Ueda, M., Sasaki, R. J. Biol. Chem. (1994) [Pubmed]
  27. Substitutions at Methionine 295 of Archaeoglobus fulgidus Ribulose-1,5-bisphosphate Carboxylase/Oxygenase Affect Oxygen Binding and CO2/O2 Specificity. Kreel, N.E., Tabita, F.R. J. Biol. Chem. (2007) [Pubmed]
  28. Nonsteroidal antiinflammatory drugs and a selective cyclooxygenase 2 inhibitor uncouple mitochondria in intact cells. Krause, M.M., Brand, M.D., Krauss, S., Meisel, C., Vergin, H., Burmester, G.R., Buttgereit, F. Arthritis Rheum. (2003) [Pubmed]
  29. Liver regeneration. Fausto, N. J. Hepatol. (2000) [Pubmed]
  30. A Role for Sterol Levels in Oxygen Sensing in Saccharomyces cerevisiae. Davies, B.S., Rine, J. Genetics (2006) [Pubmed]
  31. Downregulation of oxygen demand in isoprenaline stimulated canine myocardium. Lee, S.C., Downey, H.F. Cardiovasc. Res. (1993) [Pubmed]
  32. Activation of Vascular Endothelial Growth Factor through Reactive Oxygen Species Mediates 20-Hydroxyeicosatetraenoic Acid-Induced Endothelial Cell Proliferation. Guo, A.M., Arbab, A.S., Falck, J.R., Chen, P., Edwards, P.A., Roman, R.J., Scicli, A.G. J. Pharmacol. Exp. Ther. (2007) [Pubmed]
  33. Rox1 mediated repression. Oxygen dependent repression in yeast. Kastaniotis, A.J., Zitomer, R.S. Adv. Exp. Med. Biol. (2000) [Pubmed]
  34. Reactive Oxygen Species Mediated Sustained Activation of Protein Kinase C {alpha} and Extracellular Signal-Regulated Kinase for Migration of Human Hepatoma Cell Hepg2. Wu, W.S., Tsai, R.K., Chang, C.H., Wang, S., Wu, J.R., Chang, Y.X. Mol. Cancer Res. (2006) [Pubmed]
  35. Raman Evidence for Specific Substrate-Induced Structural Changes in the Heme Pocket of Human Cytochrome P450 Aromatase during the Three Consecutive Oxygen Activation Steps. Tosha, T., Kagawa, N., Ohta, T., Yoshioka, S., Waterman, M.R., Kitagawa, T. Biochemistry (2006) [Pubmed]
  36. The role of Fas-FasL in the development and treatment of ischemic retinopathy. Barreiro, R., Schadlu, R., Herndon, J., Kaplan, H.J., Ferguson, T.A. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  37. Effects of pentastarch-deferoxamine conjugate on lung injury after cardiopulmonary bypass. Stamler, A., Wang, S.Y., Aguirre, D.E., Sellke, F.W., Johnson, R.G. Circulation (1996) [Pubmed]
  38. Chromosomal aberrations and neutrophil activation induced by reperfusion in the ischaemic human heart. Fabiani, J.N., Farah, B., Vuilleminot, A., Lecompte, T., Emerit, I., Chardigny, C., Carpentier, A. Eur. Heart J. (1993) [Pubmed]
  39. Continuous positive airway pressure during fiberoptic bronchoscopy in hypoxemic patients. A randomized double-blind study using a new device. Maitre, B., Jaber, S., Maggiore, S.M., Bergot, E., Richard, J.C., Bakthiari, H., Housset, B., Boussignac, G., Brochard, L. Am. J. Respir. Crit. Care Med. (2000) [Pubmed]
  40. A forearm exercise screening test for mitochondrial myopathy. Jensen, T.D., Kazemi-Esfarjani, P., Skomorowska, E., Vissing, J. Neurology (2002) [Pubmed]
  41. Validation of quantitative BOLD MRI measurements in kidney: application to unilateral ureteral obstruction. Pedersen, M., Dissing, T.H., Mørkenborg, J., Stødkilde-Jørgensen, H., Hansen, L.H., Pedersen, L.B., Grenier, N., Frøkiaer, J. Kidney Int. (2005) [Pubmed]
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