Gene Review:
Nphs2 - nephrosis 2, podocin
Mus musculus
Synonyms:
AI790225, PDCN, Podocin, SRN1, podocin
- Early glomerular filtration defect and severe renal disease in podocin-deficient mice. Roselli, S., Heidet, L., Sich, M., Henger, A., Kretzler, M., Gubler, M.C., Antignac, C. Mol. Cell. Biol. (2004)
- Podocytes populate cellular crescents in a murine model of inflammatory glomerulonephritis. Moeller, M.J., Soofi, A., Hartmann, I., Le Hir, M., Wiggins, R., Kriz, W., Holzman, L.B. J. Am. Soc. Nephrol. (2004)
- Angiotensin II Type 1 Receptor Blockade Inhibits the Development and Progression of HIV-Associated Nephropathy in a Mouse Model. Hiramatsu, N., Hiromura, K., Shigehara, T., Kuroiwa, T., Ideura, H., Sakurai, N., Takeuchi, S., Tomioka, M., Ikeuchi, H., Kaneko, Y., Ueki, K., Kopp, J.B., Nojima, Y. J. Am. Soc. Nephrol. (2007)
- Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia. Garovic, V.D., Wagner, S.J., Petrovic, L.M., Gray, C.E., Hall, P., Sugimoto, H., Kalluri, R., Grande, J.P. Nephrol. Dial. Transplant. (2007)
- Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin. Schwarz, K., Simons, M., Reiser, J., Saleem, M.A., Faul, C., Kriz, W., Shaw, A.S., Holzman, L.B., Mundel, P. J. Clin. Invest. (2001)
- Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling. Huber, T.B., Hartleben, B., Kim, J., Schmidts, M., Schermer, B., Keil, A., Egger, L., Lecha, R.L., Borner, C., Pavenstädt, H., Shaw, A.S., Walz, G., Benzing, T. Mol. Cell. Biol. (2003)
- Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers. Barletta, G.M., Kovari, I.A., Verma, R.K., Kerjaschki, D., Holzman, L.B. J. Biol. Chem. (2003)
- Cultured podocytes establish a size-selective barrier regulated by specific signaling pathways and demonstrate synchronized barrier assembly in a calcium switch model of junction formation. Hunt, J.L., Pollak, M.R., Denker, B.M. J. Am. Soc. Nephrol. (2005)
- CD2-associated protein and glomerular disease. Wolf, G., Stahl, R.A. Lancet (2003)
- Retinoic Acid Inhibits HIV-1-Induced Podocyte Proliferation through the cAMP Pathway. He, J.C., Lu, T.C., Fleet, M., Sunamoto, M., Husain, M., Fang, W., Neves, S., Chen, Y., Shankland, S., Iyengar, R., Klotman, P.E. J. Am. Soc. Nephrol. (2007)
- HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN. Husain, M., D'Agati, V.D., He, J.C., Klotman, M.E., Klotman, P.E. AIDS (2005)
- Autocrine VEGF-A system in podocytes regulates podocin and its interaction with CD2AP. Guan, F., Villegas, G., Teichman, J., Mundel, P., Tufro, A. Am. J. Physiol. Renal Physiol. (2006)
- Effect of the knockdown of podocin mRNA on nephrin and alpha-actinin in mouse podocyte. Fan, Q., Ding, J., Zhang, J., Guan, N., Deng, J. Exp. Biol. Med. (Maywood) (2004)
- Cells differentiated from mouse embryonic stem cells via embryoid bodies express renal marker molecules. Kramer, J., Steinhoff, J., Klinger, M., Fricke, L., Rohwedel, J. Differentiation (2006)