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MeSH Review

Nephrotic Syndrome

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Disease relevance of Nephrotic Syndrome


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Chemical compound and disease context of Nephrotic Syndrome


Biological context of Nephrotic Syndrome


Anatomical context of Nephrotic Syndrome


Gene context of Nephrotic Syndrome


Analytical, diagnostic and therapeutic context of Nephrotic Syndrome


  1. Circulating immune complexes in steroid-responsive nephrotic syndrome. Levinsky, R.J., Malleson, P.N., Barratt, T.M., Soothill, J.F. N. Engl. J. Med. (1978) [Pubmed]
  2. Transgenic mouse model of kidney disease: insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome. Weiher, H., Noda, T., Gray, D.A., Sharpe, A.H., Jaenisch, R. Cell (1990) [Pubmed]
  3. Pathogenesis of sodium and water retention in high-output and low-output cardiac failure, nephrotic syndrome, cirrhosis, and pregnancy (2). Schrier, R.W. N. Engl. J. Med. (1988) [Pubmed]
  4. Letter: Renal vein thrombosis and nephrotic syndrome. Duffy, J.L., Letteri, J. JAMA (1976) [Pubmed]
  5. Indomethacin and the nephrotic syndrome. Shehadeh, I.H., Demers, L.M., Abt, A.B., Schoolwerth, A.C. JAMA (1979) [Pubmed]
  6. Induction of antioxidant enzymes in murine podocytes precedes injury by puromycin aminonucleoside. Vega-Warner, V., Ransom, R.F., Vincent, A.M., Brosius, F.C., Smoyer, W.E. Kidney Int. (2004) [Pubmed]
  7. Focal segmental glomerulosclerosis associated with infantile spasms in five mentally retarded children: a morphological analysis on mesangiolysis. Joh, K., Usui, N., Aizawa, S., Yamaguchi, Y., Chiba, S., Takahashi, T., Muramatsu, Y., Sakai, S. Am. J. Kidney Dis. (1991) [Pubmed]
  8. NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome. Boute, N., Gribouval, O., Roselli, S., Benessy, F., Lee, H., Fuchshuber, A., Dahan, K., Gubler, M.C., Niaudet, P., Antignac, C. Nat. Genet. (2000) [Pubmed]
  9. Treatment of the nephrotic syndrome with etanercept in patients with the tumor necrosis factor receptor-associated periodic syndrome. Drewe, E., McDermott, E.M., Powell, R.J. N. Engl. J. Med. (2000) [Pubmed]
  10. The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1. Noakes, P.G., Miner, J.H., Gautam, M., Cunningham, J.M., Sanes, J.R., Merlie, J.P. Nat. Genet. (1995) [Pubmed]
  11. Methylprednisolone plus chlorambucil as compared with methylprednisolone alone for the treatment of idiopathic membranous nephropathy. The Italian Idiopathic Membranous Nephropathy Treatment Study Group. Ponticelli, C., Zucchelli, P., Passerini, P., Cesana, B. N. Engl. J. Med. (1992) [Pubmed]
  12. Increased HLA-DR7 and increased DR2 in steroid-responsive nephrotic syndrome. Nuñez-Roldan, A., Villechenous, E., Fernandez-Andrade, C., Martin-Govantes, J. N. Engl. J. Med. (1982) [Pubmed]
  13. Long-term evaluation of chlorambucil plus prednisone in the idiopathic nephrotic syndrome of childhood. Williams, S.A., Makker, S.P., Ingelfinger, J.R., Grupe, W.E. N. Engl. J. Med. (1980) [Pubmed]
  14. The hyperlipidemia of the nephrotic syndrome. Relation to plasma albumin concentration, oncotic pressure, and viscosity. Appel, G.B., Blum, C.B., Chien, S., Kunis, C.L., Appel, A.S. N. Engl. J. Med. (1985) [Pubmed]
  15. Chlorambucil treatment of frequently relapsing nephrotic syndrome. Grupe, W.E., Makker, S.P., Ingelfinger, J.R. N. Engl. J. Med. (1976) [Pubmed]
  16. Fine mapping and haplotype analysis of the locus for congenital nephrotic syndrome on chromosome 19q13.1. Männikkö, M., Kestailä, M., Holmberg, C., Norio, R., Ryynänen, M., Olsen, A., Peltonen, L., Tryggvason, K. Am. J. Hum. Genet. (1995) [Pubmed]
  17. Genotype/phenotype correlations of NPHS1 and NPHS2 mutations in nephrotic syndrome advocate a functional inter-relationship in glomerular filtration. Koziell, A., Grech, V., Hussain, S., Lee, G., Lenkkeri, U., Tryggvason, K., Scambler, P. Hum. Mol. Genet. (2002) [Pubmed]
  18. Reduced renal medullary water channel expression in puromycin aminonucleoside--induced nephrotic syndrome. Apostol, E., Ecelbarger, C.A., Terris, J., Bradford, A.D., Andrews, P., Knepper, M.A. J. Am. Soc. Nephrol. (1997) [Pubmed]
  19. Spontaneous remission of the nephrotic syndrome in diabetic nephropathy. Pabico, R.C., Panner, B.J., McKenna, B.A., Freeman, R.B. Am. J. Med. (1975) [Pubmed]
  20. IFN-inducible protein-10 plays a pivotal role in maintaining slit-diaphragm function by regulating podocyte cell-cycle balance. Han, G.D., Suzuki, K., Koike, H., Suzuki, K., Yoneyama, H., Narumi, S., Shimizu, F., Kawachi, H. J. Am. Soc. Nephrol. (2006) [Pubmed]
  21. Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities. Dressler, G.R., Wilkinson, J.E., Rothenpieler, U.W., Patterson, L.T., Williams-Simons, L., Westphal, H. Nature (1993) [Pubmed]
  22. Nephritogenic mAb 5-1-6 is directed at the extracellular domain of rat nephrin. Topham, P.S., Kawachi, H., Haydar, S.A., Chugh, S., Addona, T.A., Charron, K.B., Holzman, L.B., Shia, M., Shimizu, F., Salant, D.J. J. Clin. Invest. (1999) [Pubmed]
  23. Macrophages from nephrotic rats regulate apolipoprotein E biosynthesis and cholesterol content independently. Bass, J., Fisher, E.A., Prack, M.M., Williams, D.L., Marsh, J.B. J. Clin. Invest. (1991) [Pubmed]
  24. Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton. Takeda, T., McQuistan, T., Orlando, R.A., Farquhar, M.G. J. Clin. Invest. (2001) [Pubmed]
  25. Can urinary thyroid hormone loss cause hypothyroidism? Fonseca, V., Thomas, M., Katrak, A., Sweny, P., Moorhead, J.F. Lancet (1991) [Pubmed]
  26. Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin. Schwarz, K., Simons, M., Reiser, J., Saleem, M.A., Faul, C., Kriz, W., Shaw, A.S., Holzman, L.B., Mundel, P. J. Clin. Invest. (2001) [Pubmed]
  27. Structure of the gene for congenital nephrotic syndrome of the finnish type (NPHS1) and characterization of mutations. Lenkkeri, U., Männikkö, M., McCready, P., Lamerdin, J., Gribouval, O., Niaudet, P.M., Antignac C, K., Kashtan, C.E., Homberg, C., Olsen, A., Kestilä, M., Tryggvason, K. Am. J. Hum. Genet. (1999) [Pubmed]
  28. Overexpression of Frat1 in transgenic mice leads to glomerulosclerosis and nephrotic syndrome, and provides direct evidence for the involvement of Frat1 in lymphoma progression. Jonkers, J., Weening, J.J., van der Valk, M., Bobeldijk, R., Berns, A. Oncogene (1999) [Pubmed]
  29. Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome. Koshikawa, M., Mukoyama, M., Mori, K., Suganami, T., Sawai, K., Yoshioka, T., Nagae, T., Yokoi, H., Kawachi, H., Shimizu, F., Sugawara, A., Nakao, K. J. Am. Soc. Nephrol. (2005) [Pubmed]
  30. Insulin-like growth factors (IGFs) and IGF binding proteins, serum acid-labile subunit and growth hormone binding protein in nephrotic children. Haffner, D., Tönshoff, B., Blum, W.F., Vickers, M., Siebler, T., Cronin, M.J., Baxter, R.C., Mehls, O. Kidney Int. (1997) [Pubmed]
  31. Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability. Liu, G., Kaw, B., Kurfis, J., Rahmanuddin, S., Kanwar, Y.S., Chugh, S.S. J. Clin. Invest. (2003) [Pubmed]
  32. Congenital nephrotic syndrome: prenatal diagnosis and genetic counselling by estimation of aminotic-fluid and maternal serum alpha-fetoprotein. Seppälä, M., Rapola, J., Huttunen, N.P., Aula, P., Karjalainen, O., Ruoslahti, E. Lancet (1976) [Pubmed]
  33. Effect of dose-intensive intravenous melphalan and autologous blood stem-cell transplantation on al amyloidosis-associated renal disease. Dember, L.M., Sanchorawala, V., Seldin, D.C., Wright, D.G., LaValley, M., Berk, J.L., Falk, R.H., Skinner, M. Ann. Intern. Med. (2001) [Pubmed]
  34. Renal amyloidosis and subcutaneous drug abuse. Meador, K.H., Sharon, Z., Lewis, E.J. Ann. Intern. Med. (1979) [Pubmed]
  35. Urinary excretion of Hageman factor (factor XII) and the presence of nonfunctional Hageman factor in the nephrotic syndrome. Saito, H., Goodnough, L.T., Makker, S.P., Kallen, R.J. Am. J. Med. (1981) [Pubmed]
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