Gene Review:
Actn1 - actinin, alpha 1
Mus musculus
Synonyms:
3110023F10Rik, Actn1a, Alpha-actinin cytoskeletal isoform, Alpha-actinin-1, F-actin cross-linking protein, ...
- Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex. Li, H.H., Kedar, V., Zhang, C., McDonough, H., Arya, R., Wang, D.Z., Patterson, C. J. Clin. Invest. (2004)
- Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin. Zhao, Z., Deocharan, B., Scherer, P.E., Ozelius, L.J., Putterman, C. J. Immunol. (2006)
- Thymic B lymphocyte clones from patients with myasthenia gravis secrete monoclonal striational autoantibodies reacting with myosin, alpha actinin, or actin. Williams, C.L., Lennon, V.A. J. Exp. Med. (1986)
- Upregulation of F-actin and alpha-actinin in reactive astrocytes. Abd-El-Basset, E.M., Fedoroff, S. J. Neurosci. Res. (1997)
- Periodic lamellipodial contractions correlate with rearward actin waves. Giannone, G., Dubin-Thaler, B.J., Döbereiner, H.G., Kieffer, N., Bresnick, A.R., Sheetz, M.P. Cell (2004)
- Coexistence of three major isoactins in a single sarcoma 180 cell. Bravo, R., Fey, S.J., Small, J.V., Larsen, P.M., Celis, J.E. Cell (1981)
- The participation of alpha-actinin in the capping of cell membrane components. Geiger, B., Singer, S.J. Cell (1979)
- Differences in elasticity of vinculin-deficient F9 cells measured by magnetometry and atomic force microscopy. Goldmann, W.H., Galneder, R., Ludwig, M., Xu, W., Adamson, E.D., Wang, N., Ezzell, R.M. Exp. Cell Res. (1998)
- alpha-Actinin and vinculin are PIP2-binding proteins involved in signaling by tyrosine kinase. Fukami, K., Endo, T., Imamura, M., Takenawa, T. J. Biol. Chem. (1994)
- N terminus is essential for tropomyosin functions: N-terminal modification disrupts stress fiber organization and abolishes anti-oncogenic effects of tropomyosin-1. Bharadwaj, S., Hitchcock-DeGregori, S., Thorburn, A., Prasad, G.L. J. Biol. Chem. (2004)
- Fine mapping of the alpha-actinin binding site within cysteine-rich protein. Harper, B.D., Beckerle, M.C., Pomiès, P. Biochem. J. (2000)
- Targeted disruption of N-RAP gene function by RNA interference: a role for N-RAP in myofibril organization. Dhume, A., Lu, S., Horowits, R. Cell Motil. Cytoskeleton (2006)
- Adult mice deficient in actinin-associated LIM-domain protein reveal a developmental pathway for right ventricular cardiomyopathy. Pashmforoush, M., Pomiès, P., Peterson, K.L., Kubalak, S., Ross, J., Hefti, A., Aebi, U., Beckerle, M.C., Chien, K.R. Nat. Med. (2001)
- Integrin-mediated cell adhesion: the cytoskeletal connection. Critchley, D.R., Holt, M.R., Barry, S.T., Priddle, H., Hemmings, L., Norman, J. Biochem. Soc. Symp. (1999)
- Plakoglobin is a component of the filamentous subplasmalemmal coat of lens cells. Franke, W.W., Kapprell, H.P., Cowin, P. Eur. J. Cell Biol. (1987)
- Extensive but coordinated reorganization of the membrane skeleton in myofibers of dystrophic (mdx) mice. Williams, M.W., Bloch, R.J. J. Cell Biol. (1999)
- Mapping in vivo associations of cytoplasmic proteins with integrin beta 1 cytoplasmic domain mutants. Lewis, J.M., Schwartz, M.A. Mol. Biol. Cell (1995)
- The lipoxygenase metabolite, 12(S)-HETE, induces a protein kinase C-dependent cytoskeletal rearrangement and retraction of microvascular endothelial cells. Tang, D.G., Timar, J., Grossi, I.M., Renaud, C., Kimler, V.A., Diglio, C.A., Taylor, J.D., Honn, K.V. Exp. Cell Res. (1993)
- Reorganization of alpha-actinin and vinculin in living cells following ATP depletion and replenishment. Wang, Y.L. Exp. Cell Res. (1986)
- Differential modulation of Ca2+/calmodulin-dependent protein kinase II activity by regulated interactions with N-methyl-D-aspartate receptor NR2B subunits and alpha-actinin. Robison, A.J., Bartlett, R.K., Bass, M.A., Colbran, R.J. J. Biol. Chem. (2005)
- Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein. Guan, J.L., Trevithick, J.E., Hynes, R.O. Cell Regul. (1991)
- Structural and functional roles of desmin in mouse skeletal muscle during passive deformation. Shah, S.B., Davis, J., Weisleder, N., Kostavassili, I., McCulloch, A.D., Ralston, E., Capetanaki, Y., Lieber, R.L. Biophys. J. (2004)
- New N-RAP-binding partners alpha-actinin, filamin and Krp1 detected by yeast two-hybrid screening: implications for myofibril assembly. Lu, S., Carroll, S.L., Herrera, A.H., Ozanne, B., Horowits, R. J. Cell. Sci. (2003)
- Localization and kinetics of protein kinase C-epsilon anchoring in cardiac myocytes. Robia, S.L., Ghanta, J., Robu, V.G., Walker, J.W. Biophys. J. (2001)
- Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner. Asanuma, K., Kim, K., Oh, J., Giardino, L., Chabanis, S., Faul, C., Reiser, J., Mundel, P. J. Clin. Invest. (2005)
- Temporal and spatial expression pattern of beta1 sodium channel subunit during heart development. Domínguez, J.N., Navarro, F., Franco, D., Thompson, R.P., Aránega, A.E. Cardiovasc. Res. (2005)
- Cytoskeletal disruption and small heat shock protein translocation immediately after lengthening contractions. Koh, T.J., Escobedo, J. Am. J. Physiol., Cell Physiol. (2004)
- Effects of oxytocin on cardiomyocyte differentiation from mouse embryonic stem cells. Hatami, L., Valojerdi, M.R., Mowla, S.J. Int. J. Cardiol. (2007)
- Ablation of Cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy. Zhou, Q., Chu, P.H., Huang, C., Cheng, C.F., Martone, M.E., Knoll, G., Shelton, G.D., Evans, S., Chen, J. J. Cell Biol. (2001)
- Organization of stress fibers in cultured fibroblasts after extraction of actin with bovine brain gelsolin-like protein. Verkhovsky, A.B., Surgucheva, I.G., Svitkina, T.M., Tint, I.S., Gelfand, V.I. Exp. Cell Res. (1987)
- Relation of retinomotor responses and contractile proteins in vertebrate retinas. Drenckhahn, D., Wagner, H.J. Eur. J. Cell Biol. (1985)
- Myofibril degeneration caused by tropomodulin overexpression leads to dilated cardiomyopathy in juvenile mice. Sussman, M.A., Welch, S., Cambon, N., Klevitsky, R., Hewett, T.E., Price, R., Witt, S.A., Kimball, T.R. J. Clin. Invest. (1998)
- Lymphocyte alpha-actinin. Relationship to cell membrane and co-capping with surface receptors. Hoessli, D., Rungger-Brändle, E., Jockusch, B.M., Gabbiani, G. J. Cell Biol. (1980)
- Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins. Koyasu, S., Nishida, E., Kadowaki, T., Matsuzaki, F., Iida, K., Harada, F., Kasuga, M., Sakai, H., Yahara, I. Proc. Natl. Acad. Sci. U.S.A. (1986)