Gene Review:
HOXA11 - homeobox A11
Homo sapiens
Synonyms:
HOX1, HOX1I, Homeobox protein Hox-1I, Homeobox protein Hox-A11
Thompson,
Nguyen,
Taylor,
Igarashi,
Olive,
Arici,
Davies,
Fisher,
Kosaki,
Kosaki,
Suzuki,
Yoshihashi,
Takahashi,
Sasaki,
Tomita,
McGinnis,
Matsuo,
Wang,
Luo,
Zhu,
Wang,
Speleman,
Cauwelier,
Dastugue,
Cools,
Verhasselt,
Poppe,
Van Roy,
Vandesompele,
Graux,
Uyttebroeck,
Boogaerts,
De Moerloose,
Benoit,
Selleslag,
Billiet,
Robert,
Huguet,
Vandenberghe,
De Paepe,
Marynen,
Hagemeijer,
- Frequent HOXA11 and THBS2 promoter methylation, and a methylator phenotype in endometrial adenocarcinoma. Whitcomb, B.P., Mutch, D.G., Herzog, T.J., Rader, J.S., Gibb, R.K., Goodfellow, P.J. Clin. Cancer Res. (2003)
- A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias. Speleman, F., Cauwelier, B., Dastugue, N., Cools, J., Verhasselt, B., Poppe, B., Van Roy, N., Vandesompele, J., Graux, C., Uyttebroeck, A., Boogaerts, M., De Moerloose, B., Benoit, Y., Selleslag, D., Billiet, J., Robert, A., Huguet, F., Vandenberghe, P., De Paepe, A., Marynen, P., Hagemeijer, A. Leukemia (2005)
- Amegakaryocytic thrombocytopenia and radio-ulnar synostosis are associated with HOXA11 mutation. Thompson, A.A., Nguyen, L.T. Nat. Genet. (2000)
- HOXA11 mutation in amegakaryocytic thrombocytopenia with radio-ulnar synostosis syndrome inhibits megakaryocytic differentiation in vitro. Horvat-Switzer, R.D., Thompson, A.A. Blood Cells Mol. Dis. (2006)
- Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract. Cheng, W., Liu, J., Yoshida, H., Rosen, D., Naora, H. Nat. Med. (2005)
- The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation. Naguibneva, I., Ameyar-Zazoua, M., Polesskaya, A., Ait-Si-Ali, S., Groisman, R., Souidi, M., Cuvellier, S., Harel-Bellan, A. Nat. Cell Biol. (2006)
- Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal translocation t(7;11)(p15;p15). Fujino, T., Suzuki, A., Ito, Y., Ohyashiki, K., Hatano, Y., Miura, I., Nakamura, T. Blood (2002)
- Alteration of homeobox gene expression by N-ras transformation of PA-1 human teratocarcinoma cells. Buettner, R., Yim, S.O., Hong, Y.S., Boncinelli, E., Tainsky, M.A. Mol. Cell. Biol. (1991)
- HOX gene expression is altered in the endometrium of women with endometriosis. Taylor, H.S., Bagot, C., Kardana, A., Olive, D., Arici, A. Hum. Reprod. (1999)
- The role of HOX genes in human implantation. Eun Kwon, H., Taylor, H.S. Ann. N. Y. Acad. Sci. (2004)
- Complete mutation analysis panel of the 39 human HOX genes. Kosaki, K., Kosaki, R., Suzuki, T., Yoshihashi, H., Takahashi, T., Sasaki, K., Tomita, M., McGinnis, W., Matsuo, N. Teratology (2002)
- Sex steroids mediate HOXA11 expression in the human peri-implantation endometrium. Taylor, H.S., Igarashi, P., Olive, D.L., Arici, A. J. Clin. Endocrinol. Metab. (1999)
- HOXA11 silencing and endogenous HOXA11 antisense ribonucleic acid in the uterine endometrium. Chau, Y.M., Pando, S., Taylor, H.S. J. Clin. Endocrinol. Metab. (2002)
- Coordinated expression of Hoxa-11 and Hoxa-13 during limb muscle patterning. Yamamoto, M., Gotoh, Y., Tamura, K., Tanaka, M., Kawakami, A., Ide, H., Kuroiwa, A. Development (1998)
- Genes and proteins in renal development. Davies, J.A., Fisher, C.E. Exp. Nephrol. (2002)
- Involvement of JNKs and p38-MAPK/MSK1 pathways in H(2)O(2)-induced upregulation of heme oxygenase-1 mRNA in H9c2 cells. Aggeli, I.K., Gaitanaki, C., Beis, I. Cell. Signal. (2006)
- Neonatal estrogenic exposure suppresses PTEN-related endometrial carcinogenesis in recombinant mice. Begum, M., Tashiro, H., Katabuchi, H., Suzuki, A., Kurman, R.J., Okamura, H. Lab. Invest. (2006)
- Yin Yang 1 Physically Interacts with Hoxa11 and Represses Hoxa11-dependent Transcription. Luke, M.P., Sui, G., Liu, H., Shi, Y. J. Biol. Chem. (2006)
- HOXC and HOXD gene expression in human endometrium: lack of redundancy with HOXA paralogs. Akbas, G.E., Taylor, H.S. Biol. Reprod. (2004)
- Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability. Williams, T.M., Williams, M.E., Heaton, J.H., Gelehrter, T.D., Innis, J.W. Nucleic Acids Res. (2005)
- Expression of HOXA11 gene in human endometrium. Wang, L.F., Luo, H.Z., Zhu, Z.M., Wang, J.D. Am. J. Obstet. Gynecol. (2004)
- Craniosynostosis and hemizygosity for D7S135 caused by a de novo and apparently balanced t(6;7) translocation. Tsuji, K., Narahara, K., Kikkawa, K., Murakami, M., Yokoyama, Y., Ninomiya, S., Seino, Y. Am. J. Med. Genet. (1994)