Gene Review:
APOB - apolipoprotein B
Bos taurus
Synonyms:
APOB-100, ApoB(100)
- An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells. Jamil, H., Gordon, D.A., Eustice, D.C., Brooks, C.M., Dickson, J.K., Chen, Y., Ricci, B., Chu, C.H., Harrity, T.W., Ciosek, C.P., Biller, S.A., Gregg, R.E., Wetterau, J.R. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Hepatic gene expression of apolipoprotein B100 during early lactation in underfed, high producing dairy cows. Gruffat, D., Durand, D., Chilliard, Y., Williams, P., Bauchart, D. J. Dairy Sci. (1997)
- Aminoguanidine inhibits the modification of proteins by lipid peroxidation derived aldehydes: a possible antiatherogenic agent. Requena, J.R., Vidal, P., Cabezas-Cerrato, J. Diabetes Res. (1992)
- Appearance of cross linked proteins in human atheroma and rat pre-fibrotic liver detected by a new monoclonal antibody. Itabe, H., Jimi, S., Kamimura, S., Suzuki, K., Uesugi, N., Imanaka, T., Shijo, H., Takano, T. Biochim. Biophys. Acta (1998)
- Lipoprotein secretion by the human hepatoma cell line Hep G2: differential rates of accumulation of apolipoprotein B and lipoprotein lipids in tissue culture media in response to albumin, glucose and oleate. Arrol, S., Mackness, M.I., Laing, I., Durrington, P.N. Biochim. Biophys. Acta (1991)
- Pause transfer: a topogenic sequence in apolipoprotein B mediates stopping and restarting of translocation. Chuck, S.L., Lingappa, V.R. Cell (1992)
- Atherogenicity of blood serum from patients with coronary heart disease. Chazov, E.I., Tertov, V.V., Orekhov, A.N., Lyakishev, A.A., Perova, N.V., Kurdanov, K.A., Khashimov, K.A., Novikov, I.D., Smirnov, V.N. Lancet (1986)
- Abetalipoproteinemia is caused by defects of the gene encoding the 97 kDa subunit of a microsomal triglyceride transfer protein. Shoulders, C.C., Brett, D.J., Bayliss, J.D., Narcisi, T.M., Jarmuz, A., Grantham, T.T., Leoni, P.R., Bhattacharya, S., Pease, R.J., Cullen, P.M. Hum. Mol. Genet. (1993)
- Oxidation of low density lipoproteins greatly enhances their association with lipoprotein lipase anchored to endothelial cell matrix. Auerbach, B.J., Bisgaier, C.L., Wölle, J., Saxena, U. J. Biol. Chem. (1996)
- Kinetics of lipolysis of very low density lipoproteins by lipoprotein lipase. Importance of particle number and noncompetitive inhibition by particles with low triglyceride content. Connelly, P.W., Maguire, G.F., Vezina, C., Hegele, R.A., Kuksis, A. J. Biol. Chem. (1994)
- Apolipoprotein B carbonyl formation is enhanced by lipid peroxidation during copper-mediated oxidation of human low-density lipoproteins. Yan, L.J., Lodge, J.K., Traber, M.G., Packer, L. Arch. Biochem. Biophys. (1997)
- Developmental changes in apolipoprotein B gene expression in the liver of fetal calves. Gruffat, D., Piot, C., Durand, D., Bauchart, D. Biol. Neonate (1998)
- Effects of milk diets containing beef tallow or coconut oil on the fatty acid metabolism of liver slices from preruminant calves. Graulet, B., Gruffat-Mouty, D., Durand, D., Bauchart, D. Br. J. Nutr. (2000)
- Effects of substituting dietary soybean protein and oil for milk protein and fat in subjects with hypercholesterolemia. Kurowska, E.M., Jordan, J., Spence, J.D., Wetmore, S., Piché, L.A., Radzikowski, M., Dandona, P., Carroll, K.K. Clinical and investigative medicine. Médecine clinique et experimentale. (1997)
- Regulation of intestinal apolipoprotein B synthesis and secretion by Caco-2 cells. Lack of fatty acid effects and control by intracellular calcium ion. Hughes, T.E., Ordovas, J.M., Schaefer, E.J. J. Biol. Chem. (1988)
- An amino-terminal fragment of apolipoprotein B binds to lipoprotein lipase and may facilitate its binding to endothelial cells. Sivaram, P., Choi, S.Y., Curtiss, L.K., Goldberg, I.J. J. Biol. Chem. (1994)
- Direct effects of growth hormone on production and secretion of apolipoprotein B from rat hepatocytes. Lindén, D., Sjöberg, A., Asp, L., Carlsson, L., Oscarsson, J. Am. J. Physiol. Endocrinol. Metab. (2000)
- Progesterone production by cultured luteal cells in the presence of bovine low- and high-density lipoproteins purified by heparin affinity chromatography. Carroll, D.J., Grummer, R.R., Mao, F.C. J. Anim. Sci. (1992)
- Oleate stimulates secretion of apolipoprotein B-containing lipoproteins from Hep G2 cells by inhibiting early intracellular degradation of apolipoprotein B. Dixon, J.L., Furukawa, S., Ginsberg, H.N. J. Biol. Chem. (1991)
- Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation. Steinbrecher, U.P., Lougheed, M., Kwan, W.C., Dirks, M. J. Biol. Chem. (1989)
- Immunologic comparison of the conformations of apolipoprotein B. Investigation of methodologies for the reconstitution of delipidated and denatured apolipoprotein B with nonionic surfactants. Kilgore, L.L., Patterson, B.W., Fisher, W.R. J. Biol. Chem. (1986)
- Effects of atorvastatin on the intracellular stability and secretion of apolipoprotein B in HepG2 cells. Mohammadi, A., Macri, J., Newton, R., Romain, T., Dulay, D., Adeli, K. Arterioscler. Thromb. Vasc. Biol. (1998)
- Demonstration of biphasic effects of docosahexaenoic acid on apolipoprotein B secretion in HepG2 cells. Wu, X., Shang, A., Jiang, H., Ginsberg, H.N. Arterioscler. Thromb. Vasc. Biol. (1997)
- A simple, rapid, and sensitive fluorescence assay for microsomal triglyceride transfer protein. Athar, H., Iqbal, J., Jiang, X.C., Hussain, M.M. J. Lipid Res. (2004)
- Synthesis and secretion of apolipoprotein E occur independently of synthesis and secretion of apolipoprotein B-containing lipoproteins in HepG2 cells. Fazio, S., Yao, Z., McCarthy, B.J., Rall, S.C. J. Biol. Chem. (1992)
- Plasma apolipoprotein secretion by human monocyte-derived macrophages. Wang-Iverson, P., Gibson, J.C., Brown, W.V. Biochim. Biophys. Acta (1985)
- Immunoquantification of total apolipoprotein B in serum by nephelometry: influence of lipase treatment and detergents. DaCol, P., Kostner, G.M. Clin. Chem. (1983)
- Stimulation of luteal cell progesterone production by lipoproteins from cows fed control or fat-supplemented diets. Carroll, D.J., Grummer, R.R., Clayton, M.K. J. Dairy Sci. (1992)
- Quantitative determination of apolipoprotein B in bovine serum by radial immunodiffusion. Marcos, E., Mazur, A., Cardot, P., Rayssiguier, Y. Comp. Biochem. Physiol., B (1989)
- Degradation of apolipoprotein B of low density lipoprotein by cultured bovine smooth muscle cells. Accumulation of intermediates in the presence of protease inhibitors. Aulinskas, T.H., Coetzee, G.A., van der Westhuyzen, D.R. Biochim. Biophys. Acta (1981)