Gene Review:
Tbce - tubulin-specific chaperone E
Mus musculus
Synonyms:
2610206D02Rik, C530005D02Rik, Tubulin-folding cofactor E, Tubulin-specific chaperone E, pmn
- Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Sendtner, M., Schmalbruch, H., Stöckli, K.A., Carroll, P., Kreutzberg, G.W., Thoenen, H. Nature (1992)
- GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice. Sagot, Y., Tan, S.A., Hammang, J.P., Aebischer, P., Kato, A.C. J. Neurosci. (1996)
- Aliphatic propargylamines as symptomatic and neuroprotective treatments for neurodegenerative diseases. Berry, M.D., Boulton, A.A. Neurotoxicology and teratology. (2002)
- A missense mutation in Tbce causes progressive motor neuronopathy in mice. Martin, N., Jaubert, J., Gounon, P., Salido, E., Haase, G., Szatanik, M., Guénet, J.L. Nat. Genet. (2002)
- Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors. Haase, G., Kennel, P., Pettmann, B., Vigne, E., Akli, S., Revah, F., Schmalbruch, H., Kahn, A. Nat. Med. (1997)
- Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease. Bommel, H., Xie, G., Rossoll, W., Wiese, S., Jablonka, S., Boehm, T., Sendtner, M. J. Cell Biol. (2002)
- Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice. Sendtner, M., Götz, R., Holtmann, B., Thoenen, H. J. Neurosci. (1997)
- Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease. Sagot, Y., Dubois-Dauphin, M., Tan, S.A., de Bilbao, F., Aebischer, P., Martinou, J.C., Kato, A.C. J. Neurosci. (1995)
- Inhibiting axon degeneration and synapse loss attenuates apoptosis and disease progression in a mouse model of motoneuron disease. Ferri, A., Sanes, J.R., Coleman, M.P., Cunningham, J.M., Kato, A.C. Curr. Biol. (2003)
- Adenovirus-mediated transfer of the neurotrophin-3 gene into skeletal muscle of pmn mice: therapeutic effects and mechanisms of action. Haase, G., Pettmann, B., Vigne, E., Castelnau-Ptakhine, L., Schmalbruch, H., Kahn, A. J. Neurol. Sci. (1998)
- Phosphatidylinositol 3-kinase activity in murine motoneuron disease: the progressive motor neuropathy mouse. Wagey, R., Lurot, S., Perrelet, D., Pelech, S.L., Sagot, Y., Krieger, C. Neuroscience (2001)
- New isomeric azine-bridged dinuclear platinum(II) complexes circumvent cross-resistance to cisplatin. Komeda, S., Kalayda, G.V., Lutz, M., Spek, A.L., Yamanaka, Y., Sato, T., Chikuma, M., Reedijk, J. J. Med. Chem. (2003)
- An inhibitor of serine proteases, neuroserpin, acts as a neuroprotective agent in a mouse model of neurodegenerative disease. Simonin, Y., Charron, Y., Sonderegger, P., Vassalli, J.D., Kato, A.C. J. Neurosci. (2006)
- Increased accumulation of transferrin by motor neurons of the mouse mutant progressive motor neuronopathy (pmn/pmn). Moos, T. J. Neurocytol. (1995)