Gene Review:
Trf - transferrin
Mus musculus
Synonyms:
AI266983, Beta-1 metal-binding globulin, Cd176, HP, Serotransferrin, ...
- Regulation of transferrin receptor 2 protein levels by transferrin. Robb, A., Wessling-Resnick, M. Blood (2004)
- Increased plasma transferrin, altered body iron distribution, and microcytic hypochromic anemia in ferrochelatase-deficient mice. Lyoumi, S., Abitbol, M., Andrieu, V., Henin, D., Robert, E., Schmitt, C., Gouya, L., de Verneuil, H., Deybach, J.C., Montagutelli, X., Beaumont, C., Puy, H. Blood (2007)
- In vivo gene delivery to tumor cells by transferrin-streptavidin-DNA conjugate. Sato, Y., Yamauchi, N., Takahashi, M., Sasaki, K., Fukaura, J., Neda, H., Fujii, S., Hirayama, M., Itoh, Y., Koshita, Y., Kogawa, K., Kato, J., Sakamaki, S., Niitsu, Y. FASEB J. (2000)
- Transferrin and its receptor in the development of genetically determined neural tube defects in the mouse embryo. Hoyle, C., Henderson, D.J., Matthews, D.J., Copp, A.J. Dev. Dyn. (1996)
- Evidence that dystroglycan is associated with dynamin and regulates endocytosis. Zhan, Y., Tremblay, M.R., Melian, N., Carbonetto, S. J. Biol. Chem. (2005)
- Accelerated plasmacytoma formation in mice treated with alpha-fetoprotein. Gershwin, M.E., Castles, J.J., Makishima, R. J. Natl. Cancer Inst. (1980)
- Anti-membrane-bound transferrin-like protein antibodies induce cell-shape change and chondrocyte differentiation in the presence or absence of concanavalin A. Oda, R., Suardita, K., Fujimoto, K., Pan, H., Yan, W., Shimazu, A., Shintani, H., Kato, Y. J. Cell. Sci. (2003)
- Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Ohgami, R.S., Campagna, D.R., Greer, E.L., Antiochos, B., McDonald, A., Chen, J., Sharp, J.J., Fujiwara, Y., Barker, J.E., Fleming, M.D. Nat. Genet. (2005)
- A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice. Lim, J.E., Jin, O., Bennett, C., Morgan, K., Wang, F., Trenor, C.C., Fleming, M.D., Andrews, N.C. Nat. Genet. (2005)
- Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis. Nicolas, G., Viatte, L., Lou, D.Q., Bennoun, M., Beaumont, C., Kahn, A., Andrews, N.C., Vaulont, S. Nat. Genet. (2003)
- Inhibition of hemoglobin production by transferrin-gallium. Chitambar, C.R., Zivkovic, Z. Blood (1987)
- Differential expression of a Mr approximately 90,000 cell surface transferrin receptor-related glycoprotein on murine B16 metastatic melanoma sublines selected for enhanced brain or ovary colonization. Nicolson, G.L., Inoue, T., Van Pelt, C.S., Cavanaugh, P.G. Cancer Res. (1990)
- Desferal inhibits breast tumor growth and does not interfere with the tumoricidal activity of doxorubicin. Hoke, E.M., Maylock, C.A., Shacter, E. Free Radic. Biol. Med. (2005)
- Release of lactoferrin by polymorphonuclear leukocytes after aerosol challenge with Escherichia coli. LaForce, F.M., Boose, D.S. Infect. Immun. (1987)
- Distribution and number of transferrin receptors in Parkinson's disease and in MPTP-treated mice. Mash, D.C., Pablo, J., Buck, B.E., Sanchez-Ramos, J., Weiner, W.J. Exp. Neurol. (1991)
- Transferrin receptor is necessary for development of erythrocytes and the nervous system. Levy, J.E., Jin, O., Fujiwara, Y., Kuo, F., Andrews, N.C. Nat. Genet. (1999)
- The molecular defect in hypotransferrinemic mice. Trenor, C.C., Campagna, D.R., Sellers, V.M., Andrews, N.C., Fleming, M.D. Blood (2000)
- Assignment of the gene coding for hepatocyte growth factor-like protein to mouse chromosome 9. Degen, S.J., Gilbert, D.J., Jenkins, N.A., Copeland, N.G. Genomics (1992)
- Transferrin receptor recycling in rat hepatocytes is regulated by protein phosphatase 2A, possibly through effects on microtubule-dependent transport. Runnegar, M., Wei, X., Berndt, N., Hamm-Alvarez, S.F. Hepatology (1997)
- Inhibition of heme synthesis decreases transferrin receptor expression in mouse erythroleukemia cells. Hradilek, A., Fuchs, O., Neuwirt, J. J. Cell. Physiol. (1992)
- Role of transferrin, transferrin receptors, and iron in macrophage listericidal activity. Alford, C.E., King, T.E., Campbell, P.A. J. Exp. Med. (1991)
- The molecular basis of ferroportin-linked hemochromatosis. De Domenico, I., Ward, D.M., Nemeth, E., Vaughn, M.B., Musci, G., Ganz, T., Kaplan, J. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse. Trinder, D., Olynyk, J.K., Sly, W.S., Morgan, E.H. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis. Chua, A.C., Olynyk, J.K., Leedman, P.J., Trinder, D. Blood (2004)
- The effect of intracellular iron concentration and nitrogen monoxide on Nramp2 expression and non-transferrin-bound iron uptake. Wardrop, S.L., Richardson, D.R. Eur. J. Biochem. (1999)
- CD71 antibody enhances iron uptake by mouse bone marrow cells and the survival potential of erythroid progenitor cells. Honda, K.I., Ishiko, O., Hato, F., Kitagawa, S., Jikihara, I., Yoshida, H., Ogita, S. Int. J. Mol. Med. (2001)
- Impaired acidification in early endosomes of ClC-5 deficient proximal tubule. Hara-Chikuma, M., Wang, Y., Guggino, S.E., Guggino, W.B., Verkman, A.S. Biochem. Biophys. Res. Commun. (2005)
- Receptor mediated and fluid phase pathways for internalization of the ER Hsp90 chaperone GRP94 in murine macrophages. Wassenberg, J.J., Dezfulian, C., Nicchitta, C.V. J. Cell. Sci. (1999)
- Increased hepcidin expression and hypoferraemia associated with an acute phase response are not affected by inactivation of HFE. Frazer, D.M., Wilkins, S.J., Millard, K.N., McKie, A.T., Vulpe, C.D., Anderson, G.J. Br. J. Haematol. (2004)
- Induction of Nramp2 in activated mouse macrophages is dissociated from regulation of the Nramp1, classical inflammatory genes, and genes involved in iron metabolism. Wardrop, S.L., Wells, C., Ravasi, T., Hume, D.A., Richardson, D.R. J. Leukoc. Biol. (2002)
- Haemoglobin synthesis in erythropoietin-stimulated J2E cells does not require increased numbers of transferrin receptors. Callus, B.A., Busfield, S.J., Rossi, E., Tilbrook, P.A., Chappell, D., Morgan, E.H., Klinken, S.P. Eur. J. Biochem. (1997)
- Similarities and differences in the regulation of N-myc and c-myc genes in murine embryonal carcinoma cells. Sejersen, T., Rahm, M., Szabo, G., Ingvarsson, S., Sümegi, J. Exp. Cell Res. (1987)
- Fetal mouse kidney maturation in vitro: coordinated influences of epidermal growth factor, transferrin and hydrocortisone. Chailler, P., Ferrari, J., Brière, N. Anat. Embryol. (1991)
- Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice. Canonne-Hergaux, F., Zhang, A.S., Ponka, P., Gros, P. Blood (2001)
- Antigen entry into early endosomes is insufficient for MHC class II processing. Niebling, W.L., Pierce, S.K. J. Immunol. (1993)
- Chromosomal localization of ceruloplasmin and transferrin genes in laboratory rats, mice and in man by hybridization with specific DNA probes. Baranov, V.S., Schwartzman, A.L., Gorbunova, V.N., Gaitskhoki, V.S., Rubtsov, N.B., Timchenko, N.A., Neifakh, S.A. Chromosoma (1987)
- Structural organization and chromosomal localization of Hyal2, a gene encoding a lysosomal hyaluronidase. Strobl, B., Wechselberger, C., Beier, D.R., Lepperdinger, G. Genomics (1998)
- Targeting of transferrin receptors in nude mice bearing A431 and LS174T xenografts with [18F]holo-transferrin: permeability and receptor dependence. Aloj, L., Jogoda, E., Lang, L., Caracò, C., Neumann, R.D., Sung, C., Eckelman, W.C. J. Nucl. Med. (1999)
- Cloning, characterization, and modeling of a monoclonal anti-human transferrin antibody that competes with the transferrin receptor. Orlandini, M., Santucci, A., Tramontano, A., Neri, P., Oliviero, S. Protein Sci. (1994)
- Partial characterization of the human serum transferrin epitope reactive with the monoclonal antibody TRC-2. Oztürk, S., Cirakoglu, B., Bermek, E. Hybrid. Hybridomics (2003)
- Exogenous transferrin is taken up and localized by the neurulation-stage mouse embryo in vitro. Copp, A.J., Estibeiro, J.P., Brook, F.A., Downs, K.M. Dev. Biol. (1992)