Gene Review:
SIGLEC5 - sialic acid binding Ig-like lectin 5
Homo sapiens
Synonyms:
CD170, CD33 antigen-like 2, CD33L2, OB-BP2, OB-binding protein 2, ...
- Loss of Siglec expression on T lymphocytes during human evolution. Nguyen, D.H., Hurtado-Ziola, N., Gagneux, P., Varki, A. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Characterization of siglec-5, a novel glycoprotein expressed on myeloid cells related to CD33. Cornish, A.L., Freeman, S., Forbes, G., Ni, J., Zhang, M., Cepeda, M., Gentz, R., Augustus, M., Carter, K.C., Crocker, P.R. Blood (1998)
- Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates. Angata, T., Hayakawa, T., Yamanaka, M., Varki, A., Nakamura, M. FASEB J. (2006)
- Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation. Avril, T., Freeman, S.D., Attrill, H., Clarke, R.G., Crocker, P.R. J. Biol. Chem. (2005)
- Characterization of Siglec-5 (CD170) expression and functional activity of anti-Siglec-5 antibodies on human phagocytes. Erickson-Miller, C.L., Freeman, S.D., Hopson, C.B., D'Alessio, K.J., Fischer, E.I., Kikly, K.K., Abrahamson, J.A., Holmes, S.D., King, A.G. Exp. Hematol. (2003)
- OB-BP1/Siglec-6. a leptin- and sialic acid-binding protein of the immunoglobulin superfamily. Patel, N., Brinkman-Van der Linden, E.C., Altmann, S.W., Gish, K., Balasubramanian, S., Timans, J.C., Peterson, D., Bell, M.P., Bazan, J.F., Varki, A., Kastelein, R.A. J. Biol. Chem. (1999)
- A comparative study of the asparagine-linked oligosaccharides on siglec-5, siglec-7 and siglec-8, expressed in a CHO cell line, and their contribution to ligand recognition. Freeman, S., Birrell, H.C., D'Alessio, K., Erickson-Miller, C., Kikly, K., Camilleri, P. Eur. J. Biochem. (2001)
- Ganglioside binding pattern of CD33-related siglecs. Rapoport, E., Mikhalyov, I., Zhang, J., Crocker, P., Bovin, N. Bioorg. Med. Chem. Lett. (2003)
- Human Siglec-5: tissue distribution, novel isoforms and domain specificities for sialic acid-dependent ligand interactions. Connolly, N.P., Jones, M., Watt, S.M. Br. J. Haematol. (2002)
- Alteration and acquisition of Siglecs during in vitro maturation of CD34+ progenitors into human mast cells. Yokoi, H., Myers, A., Matsumoto, K., Crocker, P.R., Saito, H., Bochner, B.S. Allergy (2006)
- New aspects of siglec binding specificities, including the significance of fucosylation and of the sialyl-Tn epitope. Sialic acid-binding immunoglobulin superfamily lectins. Brinkman-Van der Linden, E.C., Varki, A. J. Biol. Chem. (2000)
- Group B streptococcal capsular sialic acids interact with siglecs (immunoglobulin-like lectins) on human leukocytes. Carlin, A.F., Lewis, A.L., Varki, A., Nizet, V. J. Bacteriol. (2007)
- Identification of the CD33-related Siglec receptor, Siglec-5 (CD170), as a useful marker in both normal myelopoiesis and acute myeloid leukaemias. Virgo, P., Denning-Kendall, P.A., Erickson-Miller, C.L., Singha, S., Evely, R., Hows, J.M., Freeman, S.D. Br. J. Haematol. (2003)
- Assignment of the human OB binding protein-2 gene (CD33L2) to chromosome 19q13.3 by radiation hybrid mapping. Kim, H.S. Cytogenet. Cell Genet. (1999)