Gene Review:
mutL - methyl-directed mismatch repair protein
Escherichia coli str. K-12 substr. MG1655
Synonyms:
ECK4166, JW4128
- mutA and mutC: two mutator loci in Escherichia coli that stimulate transversions. Michaels, M.L., Cruz, C., Miller, J.H. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Identification and characterization of the mutL and mutS gene products of Salmonella typhimurium LT2. Pang, P.P., Lundberg, A.S., Walker, G.C. J. Bacteriol. (1985)
- Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction. Glickman, B.W., Radman, M. Proc. Natl. Acad. Sci. U.S.A. (1980)
- Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2. Narayanan, L., Fritzell, J.A., Baker, S.M., Liskay, R.M., Glazer, P.M. Proc. Natl. Acad. Sci. U.S.A. (1997)
- The mismatch repair system (mutS, mutL and uvrD genes) in Pseudomonas aeruginosa: molecular characterization of naturally occurring mutants. Oliver, A., Baquero, F., Blázquez, J. Mol. Microbiol. (2002)
- DNA mismatch repair. Kunkel, T.A., Erie, D.A. Annu. Rev. Biochem. (2005)
- The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants. Rayssiguier, C., Thaler, D.S., Radman, M. Nature (1989)
- Mammalian DNA mismatch repair. Buermeyer, A.B., Deschênes, S.M., Baker, S.M., Liskay, R.M. Annu. Rev. Genet. (1999)
- Mismatch repair: mechanisms and relationship to cancer susceptibility. Kolodner, R.D. Trends Biochem. Sci. (1995)
- The extreme mutator effect of Escherichia coli mutD5 results from saturation of mismatch repair by excessive DNA replication errors. Schaaper, R.M., Radman, M. EMBO J. (1989)
- Products of DNA mismatch repair genes mutS and mutL are required for transcription-coupled nucleotide-excision repair of the lactose operon in Escherichia coli. Mellon, I., Champe, G.N. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Mutagenic and comutagenic effects of ethionine in Escherichia coli K12. Zgaga, Z. Mutat. Res. (1986)
- Differential effects of cisplatin and MNNG on dna mutants of Escherichia coli. Calmann, M.A., Marinus, M.G. Mutat. Res. (2005)
- DNA mismatch repair and acquired cisplatin resistance in E. coli and human ovarian carcinoma cells. Massey, A., Offman, J., Macpherson, P., Karran, P. DNA Repair (Amst.) (2003)
- The mutL repair gene of Escherichia coli K-12 forms a superoperon with a gene encoding a new cell-wall amidase. Tsui, H.C., Zhao, G., Feng, G., Leung, H.C., Winkler, M.E. Mol. Microbiol. (1994)
- Structure of Escherichia coli K-12 miaA and characterization of the mutator phenotype caused by miaA insertion mutations. Connolly, D.M., Winkler, M.E. J. Bacteriol. (1991)
- Bacterial genes mutL, mutS, and dcm participate in repair of mismatches at 5-methylcytosine sites. Lieb, M. J. Bacteriol. (1987)
- DNA mismatch-repair in Escherichia coli counteracting the hydrolytic deamination of 5-methyl-cytosine residues. Zell, R., Fritz, H.J. EMBO J. (1987)
- Mutation in Escherichia coli under starvation conditions: a new pathway leading to small deletions in strains defective in mismatch correction. Bridges, B.A., Timms, A.R. EMBO J. (1997)
- Interaction of MutS and Vsr: some dominant-negative mutS mutations that disable methyladenine-directed mismatch repair are active in very-short-patch repair. Lieb, M., Rehmat, S., Bhagwat, A.S. J. Bacteriol. (2001)
- Mutator mutations in Escherichia coli induced by the insertion of phage mu and the transposable resistance elements Tn5 and Tn10. Siegel, E.C., Wain, S.L., Meltzer, S.F., Binion, M.L., Steinberg, J.L. Mutat. Res. (1982)
- Genetic and physiological relationships among the miaA gene, 2-methylthio-N6-(delta 2-isopentenyl)-adenosine tRNA modification, and spontaneous mutagenesis in Escherichia coli K-12. Connolly, D.M., Winkler, M.E. J. Bacteriol. (1989)
- Transcriptional patterns of the mutL-miaA superoperon of Escherichia coli K-12 suggest a model for posttranscriptional regulation. Tsui, H.C., Winkler, M.E. Biochimie (1994)
- Oxygen limitation modulates pH regulation of catabolism and hydrogenases, multidrug transporters, and envelope composition in Escherichia coli K-12. Hayes, E.T., Wilks, J.C., Sanfilippo, P., Yohannes, E., Tate, D.P., Jones, B.D., Radmacher, M.D., BonDurant, S.S., Slonczewski, J.L. BMC Microbiol. (2006)
- Isolation and characterization of Dam+ revertants and suppressor mutations that modify secondary phenotypes of dam-3 strains of Escherichia coli K-12. McGraw, B.R., Marinus, M.G. Mol. Gen. Genet. (1980)