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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Inlays

  • MATERIALS AND METHODS: We treated 100 boys with a mean age of 11 months at surgery who had coronal to mid shaft hypospadias with split prepuce in situ onlay hypospadias repair [1].
  • Three techniques combining the shaping of calvarial and facial bone with onlay of methyl methacrylate are presented for use in the late treatment of unilateral coronal synostosis deformities [2].
  • They were randomized and underwent elective repair of umbilical hernia using either the PHS (n = 17), Mayo repair (n = 18), or onlay repair with mesh (n = 15) [3].
  • A study using rabbits was designed to determine if Histoacryl could be used safely to overcome the technical difficulties (graft migration during healing and cartilage fracture during suturing) often encountered when performing autogenous onlay cartilage grafting [4].
  • The restoration of a progressive delayed disocclusion on periodontally healthy canines by etched porcelain onlays has been presented as a suitable treatment alternative to interrupt bruxism and reverse destructive occlusal neuroses [5].

High impact information on Inlays

  • MPG was performed with a transverse pedicled preputial island flap as an onlay in 29 cases (74%) [6].
  • The objective of this study was calculation of damage in porcelain MOD inlays by utilization of a finite-element (FE) implementation of the distributed crack theory. "Damage" is defined as the parameter that describes the local decrease of stiffness caused by microdefects [7].
  • They included: MAGPI (92), ARAP (78), Mathieu (205), Mustarde (12), Duckett's tubularized preputial flap (142) and Onlay preputial flap (15) [8].
  • OBJECTIVE: The aim of the present study was to clinically evaluate the effect of two different adhesive/resin composite combinations for luting of IPS Empress inlays [9].
  • Distraction osteogenesis versus autogenous onlay grafting. Part II: biology of regenerate and onlay bone [10].

Chemical compound and disease context of Inlays


Biological context of Inlays


Anatomical context of Inlays

  • MATERIALS AND METHODS: Extracted human premolars were prepared to receive mesio-occlusodistal (MOD) ceramic inlays, for which 10 Denzir, 10 IPS Empress, and 10 Opc were fabricated [13].
  • CONCLUSION: After four years, extensive IPS Empress inlays and onlays bonded with the dentin bonding system Syntac Classic were found to have a 7% failure rate with 79% of the remaining restorations having marginal deficiencies [14].
  • For this purpose, a standardized onlay preparation was prepared in 12 extracted molars, and either OptiBond FL (Kerr) or Syntac Classic (Vivadent) was applied to half of the teeth and cured in the absence of oxygen (air blocking) [15].
  • The aim of this study is to evaluate a surgical protocol for vertical ridge augmentation in the maxilla and mandible using autogenous onlay bone graft associated with a titanium mesh [16].
  • This controlled clinical study evaluated the performance of IPS Empress inlays and onlays with cuspal replacements and proximal margins below the cementoenamel junction over six years of clinical service [17].

Associations of Inlays with chemical compounds

  • The defect in the cranial vault was restored with performed methyl methacrylate onlay plates [18].
  • Finishing and polishing of indirect composite and ceramic inlays in-vivo: occlusal surfaces [19].
  • Margin quality of titanium and high-gold inlays and onlays--a clinical study [20].
  • The usefulness of these previously undescribed data may be in their extrapolation to onlay grafts of coralline hydroxyapatite in maxillofacial reconstruction in humans [21].
  • Leucite-reinforced glass ceramic inlays after six years: wear of luting composites [22].

Gene context of Inlays

  • It can be concluded that the CAD/CAM inlays processed of the two ceramics functioned well during the 8-yr follow-up period [23].
  • Group 1: The ceramic inlays of Group 1 were luted using Excite DSC and an experimental self-curing resin cement (Multilink, Vivadent); in this group, Excite DSC was self-activated and not light-cured [24].
  • RelyXARC showed a significantly better adaptation to P60 inlays compared with the leucite-reinforced Empress ceramic but not the Vitablocs Mark II ceramic [25].
  • In four patients with equal length femoral nonunions, the human bone morphogenetic protein/allogeneic, autolysed antigen-free implant was placed as an medical femoral shaft onlay graft [26].
  • An accurate CCD optical laser scanner system was used for morphological measurement of the marginal change of ceramic inlays [27].

Analytical, diagnostic and therapeutic context of Inlays


  1. The split prepuce in situ onlay hypospadias repair. Rushton, H.G., Belman, A.B. J. Urol. (1998) [Pubmed]
  2. Late surgical treatment of unilateral coronal synostosis using methyl methacrylate. Persing, J.A., Cronin, A.J., Delashaw, J.B., Edgerton, M.T., Henson, S.L., Jane, J.A. J. Neurosurg. (1987) [Pubmed]
  3. Umbilical hernia repair with the prolene hernia system. Polat, C., Dervisoglu, A., Senyurek, G., Bilgin, M., Erzurumlu, K., Ozkan, K. Am. J. Surg. (2005) [Pubmed]
  4. Review of cyanoacrylate tissue glues with emphasis on their otorhinolaryngological applications. Ronis, M.L., Harwick, J.D., Fung, R., Dellavecchia, M. Laryngoscope (1984) [Pubmed]
  5. Restoration of canine disocclusion by using etched porcelain onlays. Glaser, C.G., Nagy, W.W. The Journal of prosthetic dentistry. (1991) [Pubmed]
  6. Masculinizing genitoplasty in intersex patients. Chertin, B., Koulikov, D., Hadas-Halpern, I., Farkas, A. J. Urol. (2005) [Pubmed]
  7. Distributed crack analysis of ceramic inlays. Peters, M.C., de Vree, J.H., Brekelmans, W.A. J. Dent. Res. (1993) [Pubmed]
  8. One-stage hypospadias repair. Experience with 544 cases. Ghali, A.M., el-Malik, E.M., al-Malki, T., Ibrahim, A.H. Eur. Urol. (1999) [Pubmed]
  9. Ceramic inlays bonded with two adhesives after 4 years. Krämer, N., Ebert, J., Petschelt, A., Frankenberger, R. Dental materials : official publication of the Academy of Dental Materials. (2006) [Pubmed]
  10. Distraction osteogenesis versus autogenous onlay grafting. Part II: biology of regenerate and onlay bone. Hodges, N.E., Perry, M., Mohamed, W., Hallmon, W.W., Rees, T., Opperman, L.A. The International journal of oral & maxillofacial implants. (2006) [Pubmed]
  11. Visor osteotomy augmentation of the mandible with posterior onlay bone graft or with hydroxylapatite: a comparative study. Mercier, P., Zeltser, C. Oral Surg. Oral Med. Oral Pathol. (1986) [Pubmed]
  12. Osseointegration of titanium fixtures in onlay grafting procedures with autogenous bone and hydroxylapatite. An experimental histometric study. Schliephake, H., van den Berghe, P., Neukam, F.W. Clinical oral implants research. (1991) [Pubmed]
  13. Interface gap size of manually and CAD/CAM-manufactured ceramic inlays/onlays in vitro. Addi, S., Hedayati-Khams, A., Poya, A., Sjögren, G. Journal of dentistry. (2002) [Pubmed]
  14. IPS Empress inlays and onlays after four years--a clinical study. Krämer, N., Frankenberger, R., Pelka, M., Petschelt, A. Journal of dentistry. (1999) [Pubmed]
  15. Immediate dentin sealing of onlay preparations: thickness of pre-cured Dentin Bonding Agent and effect of surface cleaning. Stavridakis, M.M., Krejci, I., Magne, P. Operative dentistry. (2005) [Pubmed]
  16. Vertical alveolar ridge augmentation by means of a titanium mesh and autogenous bone grafts. Roccuzzo, M., Ramieri, G., Spada, M.C., Bianchi, S.D., Berrone, S. Clinical oral implants research. (2004) [Pubmed]
  17. Leucite-reinforced glass ceramic inlays and onlays after six years: clinical behavior. Frankenberger, R., Petschelt, A., Krämer, N. Operative dentistry. (2000) [Pubmed]
  18. Agenesis of parietal bones with restoration of the cranial vault. Case report. Sela, M., Sahar, A., Lewin-Epstein, J. J. Neurosurg. (1979) [Pubmed]
  19. Finishing and polishing of indirect composite and ceramic inlays in-vivo: occlusal surfaces. Jung, M., Wehlen, O., Klimek, J. Operative dentistry. (2004) [Pubmed]
  20. Margin quality of titanium and high-gold inlays and onlays--a clinical study. Wolf, B.H., Walter, M.H., Boening, K.W., Schmidt, A.E. Dental materials : official publication of the Academy of Dental Materials. (1998) [Pubmed]
  21. The rate of vascularization of coralline hydroxyapatite. Grenga, T.E., Zins, J.E., Bauer, T.W. Plast. Reconstr. Surg. (1989) [Pubmed]
  22. Leucite-reinforced glass ceramic inlays after six years: wear of luting composites. Krämer, N., Frankenberger, R. Operative dentistry. (2000) [Pubmed]
  23. An 8-year evaluation of sintered ceramic and glass ceramic inlays processed by the Cerec CAD/CAM system. Pallesen, U., van Dijken, J.W. Eur. J. Oral Sci. (2000) [Pubmed]
  24. Marginal integrity of ceramic inlays luted with a self-curing resin system. Ferrari, M., Dagostin, A., Fabianelli, A. Dental materials : official publication of the Academy of Dental Materials. (2003) [Pubmed]
  25. Marginal quality of tooth-colored restorations in class II cavities after artificial aging. Manhart, J., Schmidt, M., Chen, H.Y., Kunzelmann, K.H., Hickel, R. Operative dentistry. (2001) [Pubmed]
  26. Human bone morphogenetic protein allografting for reconstruction of femoral nonunion. Johnson, E.E., Urist, M.R. Clin. Orthop. Relat. Res. (2000) [Pubmed]
  27. Quantitative measurement of marginal disintegration of ceramic inlays. Hayashi, M., Tsubakimoto, Y., Takeshige, F., Ebisu, S. Operative dentistry. (2004) [Pubmed]
  28. Porous hydroxyapatite as an onlay bone-graft substitute for maxillofacial surgery. Salyer, K.E., Hall, C.D. Plast. Reconstr. Surg. (1989) [Pubmed]
  29. The Max Schapero Memorial Award Lecture 2004: contact lenses on and in the cornea, what the eye needs. Sweeney, D.F. Optometry and vision science : official publication of the American Academy of Optometry. (2006) [Pubmed]
  30. Alumina ceramic bearings for hip endoprostheses: the Austrian experiences. Boehler, M., Plenk, H., Salzer, M. Clin. Orthop. Relat. Res. (2000) [Pubmed]
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