Disease relevance of Surgery, Oral

• The analgesic efficiency of ketamine and pethidine was compared in experimental ischemic pain and postoperative pain after oral surgery [1].
• Tranexamic acid significantly reduced mean blood losses after oral surgery in patients with haemophilia and was effective as a mouthwash in dental patients receiving oral anticoagulants [2].
• We examined the analgesic effect of racemic ketamine and its 2 enantiomers in 16 female patients (age: 20-29 years) suffering acute pain after oral surgery and in 7 female patients (age: 42-79 years) suffering chronic neuropathic orofacial pain [3].
• Droperidol-treated PONV and bilateral mandibular fracture after maxillofacial surgery [4].
• Patients scheduled for maxillofacial surgery were randomly assigned to receive isoflurane (n = 22) or nitroglycerin (n = 18) in order to induce hypotension [5].

Psychiatry related information on Surgery, Oral

• This study compares the amnesia produced in patients sedated with midazolam or diazepam or in combination with fentanyl during oral surgery [6].

High impact information on Surgery, Oral

• Hemostatic effect of tranexamic acid mouthwash in anticoagulant-treated patients undergoing oral surgery [7].
• There also is some evidence that acetaminophen can reduce swelling in inflammatory conditions other than arthritis (eg, in patients who have had oral surgery) [8].
• In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model [9].
• METHODS: Analgesic efficacy of intravenous LY293558 (0.4 or 1.2 mg/kg) was compared with that of intravenous ketorolac tromethamine (INN, ketorolac; 30 mg) and placebo in a randomized, double-blind, parallel-group study after oral surgery (n = 70) [10].
• This study evaluated whether administration of the pharmacologically active S(+)-isomer of ibuprofen suppresses acute pain and plasma beta-endorphin levels in the oral surgery model of acute pain [11].

Chemical compound and disease context of Surgery, Oral

• Samples of blood, saliva, gingiva, and alveolar bone were collected during oral surgery, 12 hours, and 2.5, 4.5, and 6.5 days after the last dosing, and the azithromycin concentration was measured microbiologically by using Micrococcus luteus NCTC 8440 as the reference organism [12].
• A number of controlled clinical trials showed that meclofenamic acid is an excellent analgesic, offering good tolerability when used in oral surgery, dysodontiasis, avulsion of the third impacted molar, and periodontitis [13].
• A comparison of amnesia in outpatients sedated with midazolam or diazepam alone or in combination with fentanyl during oral surgery [6].
• Nalbuphine produced less respiratory depression and should be considered a suitable alternative to fentanyl for use in medically compromised patients undergoing oral surgery [14].
• Ketorolac vs tramadol in the treatment of postoperative pain during maxillofacial surgery [15].

Biological context of Surgery, Oral

• A composite polymer/tricalcium phosphate membrane for guided bone regeneration in maxillofacial surgery [16].
• A series of three clinical trials in the oral surgery model evaluated the analgesic efficacy and pharmacokinetics of ketoprofen administered locally as a strategy for decreasing systemic exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) [17].
• Osseointegration with endosseous titanium implants is frequently used in oral surgery [18].
• SETTING: Departments of Biomedical Engineering, Oral/Maxillofacial Surgery, and Oral Medicine, Pathology and Oncology at the University of Michigan. RESULTS: Results showed that the design/fabrication approach could create scaffolds with designed porous architecture to match craniofacial anatomy [19].
• In a prospective, double-blind, randomized study involving 54 patients, tramadol was compared with oxycodone in PCA after maxillofacial surgery [20].

Anatomical context of Surgery, Oral

• An infusion of propofol was compared with intravenous boluses of diazepam as sedation for minor oral surgery under local anaesthesia in 12 healthy patients who had elective bilateral surgical extraction of lower third molars; the patients served as their own controls [21].
• Platelet-rich plasma (PRP) has been introduced to the field of oral and maxillofacial surgery for a decade, but its beneficial effects on maxillary sinus augmentation remain unclear [22].
• Examination of Kliostom in the prophylaxis of oral surgery cases and treatment of microbial diseases of the oral mucosa [23].
• MATERIAL AND METHODS: Ten maxillary central incisors were obtained from Division of Maxillofacial Surgery, King Saud University, College of Dentistry. Twenty specimen were prepared, they were divided into 4 groups (1) Butler toothbrush; (2) Aquafresh toothbrush; (3) Miswak; (4) Control group [24].
• Long-acting local anaesthetics in oral surgery. Clinical evaluation of bupivacaine and etidocaine for mandibular nerve block [25].

Associations of Surgery, Oral with chemical compounds

• Combining diclofenac with acetaminophen or acetaminophen-codeine after oral surgery: a randomized, double-blind single-dose study [26].
• Analgesic efficacy of bromfenac, ibuprofen, and aspirin in postoperative oral surgery pain [27].
• In oral surgery patients, tissue levels of immunoreactive bradykinin peaked approximately 3 hours after surgery [28].
• The objective of this study was to compare the analgesic efficacy of tramadol/acetaminophen (APAP) (total dose 75 mg/650 mg) and tramadol (total dose 100 mg) for the control of pain after oral surgery [29].
• In acute post-surgical pain, single-dose valdecoxib 40 mg had a rapid onset of action, provided similar analgesia to oxycodone 10 mg plus paracetamol (acetaminophen) 1000 mg and provided a longer time to rescue medication than rofecoxib or oxycodone/paracetamol after oral surgery [30].

Gene context of Surgery, Oral

• Three replicate studies in the oral surgery model of acute pain used submucosal microdialysis sample collection for the measurement of prostaglandin E2 (PGE2; a product of both COX-1 and COX-2) and thromboxane B2 (as a biomarker for COX-1 activity) with parallel assessments of pain [31].
• CONCLUSIONS: PGE(1)-induced hypotension has an effect on IL-6 response to oral and maxillofacial surgery [32].
• We determined the intra- and postoperative plasma concentrations of cytokines (tumor necrosis factor [TNF]-Alpha, interleukin [IL]-1Beta, IL-6, and IL-8) in oral surgery patients with procedures ranging in duration from 20 to 375 min and investigated their relationship to the intensity of the surgical stress over time [33].
• These data indicate that pretreatments with a single dose of a histamine receptor antagonist specific for either the H1- or H2-receptor does not produce analgesia in an oral surgery model of acute pain with overall assay sensitivity, suggesting that antihistamines that act primarily at peripheral sites are devoid of analgesic activity [34].
• First experiences with recombinant human bone morphogenetic protein 7 (osteogenic protein 1) in a human case in maxillofacial surgery [35].

Analytical, diagnostic and therapeutic context of Surgery, Oral

• The relationship between concentrations in serum and levels in tissue of flurithromycin, a new fluorinated macrolide, was determined in patients undergoing maxillofacial surgery and thoracotomy [36].
• Cardiac dysrhythmias during oral surgery. Comparison of hyoscine and droperidol premedication [37].
• Temazepam elixir 30 mg by mouth was compared with i.v. Diazemuls titrated to a maximum dose of 20 mg in a double-blind study of 50 patients undergoing elective minor oral surgery [38].
• Two patients with nasopharyngeal carcinoma, radiotherapy treatment and 'difficult' airways were anaesthetised for oral surgery [39].
• The efficacy of preoperative versus postoperative rofecoxib for preventing acute postoperative dental pain: a prospective randomized crossover study using bilateral symmetrical oral surgery [40].

References