Disease relevance of Hemangioma, Cavernous

• PURPOSE: To determine if hepatic metastases can be distinguished from cavernous hemangiomas by pattern analysis of magnetic resonance (MR) images obtained prior to and following administration of gadoteridol at standard (0.1 mmol/kg) and triple (0.3 mmol/kg) doses [1].
• Diffuse oral facial cavernous hemangioma causing severe airway obstruction after intramuscular ketamine [2].
• The treatment of a patient with progressive neurologic deficit secondary to a cavernous angioma located in the dorsal midline of the upper-most cervical spinal cord was described [3].
• Their abnormalities included tuberous sclerosis (N = 4), tumors (N = 2), an arteriovenous malformation later diagnosed as a tumor, a cavernous angioma, cerebral malformations (N = 3), and other abnormalities (N = 3) [4].
• The preliminary evidence in support of radiosurgical treatment and the recent experience with gamma knife treatment for epilepsy associated with mesial temporal sclerosis, cavernous angioma, and hypothalamic hamartoma or other lesions are presented [5].

High impact information on Hemangioma, Cavernous

• Truncating mutations in CCM1, encoding KRIT1, cause hereditary cavernous angiomas [6].
• Anticipation in familial cavernous angioma: a study of 52 families from International Familial Cavernous Angioma Study. IFCAS Group [7].
• The cerebral, cutaneous, and i.m. lesions consisted of blood-filled cysts, histologically similar to human cavernous hemangiomas and stained positive for proliferating cell nuclear antigen, urokinase-type plasminogen activator, and vascular endothelial growth factor [8].
• Interictal cerebral metabolism and epilepsy in cavernous angiomas [9].
• We studied glucose metabolism in brain tissue surrounding cavernous angioma in 22 patients, using PET, and evaluated its relation to the size, site and epileptogenic nature of the vascular malformation, as well as to the post-surgical seizure outcome [9].

Chemical compound and disease context of Hemangioma, Cavernous

• High levels of glycine and serine as a cause of the seizure symptoms of cavernous angiomas [10]?
• Iodine-131-labeled lipiodol retention within hepatic cavernous hemangioma [11].
• An 111In-octreotide scan performed on a 6-wk old girl showed increased uptake in a subcutaneous cavernous hemangioma, which should be added to the list of lesions that can be visualized on an octreotide scan [12].
• Compared with normal brain tissue, there was a marked increase in the levels of serine (fivefold), glycine (10-fold), and ethanolamine (20-fold) in the peripheral zone of the cavernous angiomas [10].
• Combination treatment for massive cavernous hemangioma of the face: YAG laser photocoagulation plus direct steroid injection followed by YAG laser resection with sapphire scalpel tips, aided by superselective embolization [13].

Biological context of Hemangioma, Cavernous

• Alternatively, since local elaboration of TPA is common to both chronic subdural membranes and cavernous angiomas, this finding may represent a more global characteristic of fibrinolytic homeostasis in cerebral tissues [14].

Anatomical context of Hemangioma, Cavernous

• Technetium tc 99m-labeled red blood cells in the preoperative diagnosis of cavernous hemangioma and other vascular orbital tumors [15].

Gene context of Hemangioma, Cavernous

• Progesterone receptor expression in orbital cavernous hemangiomas [16].
• Immunohistochemically identifiable tissue plasminogen activator in cavernous angioma: mechanism for re-hemorrhage and lesion growth [14].
• By analogy, we sought to identify whether TPA is located in tissues in and around cavernous angiomas [14].
• We report a case of a cavernous hemangioma of the iris in a 3-month-old infant treated surgically, and the histopathological findings and immunohistochemical analysis with vascular markers (factor VIII and CD34) are also shown [17].
• Small hepatocellular carcinoma versus small cavernous hemangioma: differentiation with MR imaging at 2.0 T [18].

Analytical, diagnostic and therapeutic context of Hemangioma, Cavernous

• OBJECTIVES: To evaluate technetium Tc 99m (99mTc) red blood cell scintigraphy as a diagnostic tool for orbital cavernous hemangioma and to differentiate between orbital masses on the basis of their vascularization [15].
• Sclerotherapy with polidocanol was carried out mostly at monstrous or rapidly growing cavernous hemangiomas mainly localized in the face [19].
• We conclude that the intraarterial injection of Lipiodol may not be reliable in differentiating hepatocellular carcinoma from cavernous hemangioma of the liver [20].
• Brain glucose metabolism with [18F]-fluorodeoxyglucose and positron emission tomography before and after surgical resection of epileptogenic cavernous angiomas [21].
• METHODS: Eight patients (five male, three female; mean age +/- SD = 47.75 +/- 8.59 years) with symptomatic cavernous hemangiomas of the liver were treated by TAE with polyvinyl alcohol particles or gelfoam and steel coils (single session) followed by supportive treatment [22].

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