Disease relevance of Injections, Intra-Arterial

• We have investigated the incidence and organ distribution of experimental metastases after systemic intra-arterial injection of B16-G3.26 melanoma cells into mutant Sl/Sld and W/Wv mice [1].
• CONCLUSIONS: Our data show that the intra-arterial injection of nimodipine just before and during reperfusion reduced neocortical infarct volume in rats subjected to partially reversible focal cerebral ischemia [2].
• This study investigates the in vivo glucose utilization of various immune-competent cells after an intra-arterial injection of a nonlethal dose (30 micrograms/kg body weight) of murine recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF) [3].
• 2. In the decerebrate state, the intra-arterial injection of bradykinin had little or no effect [4].
• Gastrinomas: localization by means of selective intraarterial injection of secretin [5].

Psychiatry related information on Injections, Intra-Arterial

• We studied the effects of close intra-arterial injections of substance P on colonic motor activity in the conscious state, during anesthesia, and during acute laparotomy [6].

High impact information on Injections, Intra-Arterial

• Continuous axillary plexus block in the treatment of accidental intraarterial injection of cocaine [7].
• Accidental intra-arterial injection of penicillin G. A preventable catastrophe [8].
• FINDINGS: TCAs of gentamicin and clindamycin with TVA-Bier were significantly higher compared with intravenous or intra-arterial injection [9].
• METHODS: Pancreatic exocrine and endocrine functions were stimulated by an intra-arterial injection of cholecystokinin (10(-12) mol) and intravenous injection of glucose and arginine (1 g/kg body wt), respectively [10].
• A transection and reanastomosis in the mid-small intestine blocked the reflex inhibition by close intraarterial injection of neostigmine beyond the transection site [11].

Chemical compound and disease context of Injections, Intra-Arterial

• Ventilatory and cardiac responses to hypoxia, sodium cyanide (NaCN), and intra-arterial injection of atropine, noradrenaline and DL-propranolol were investigated in the neotenous axolotl (Ambystoma mexicanum) [12].
• We describe two patients who had cerebral vasospasm after subarachnoid hemorrhage that was refractory to intraarterial injection of papaverine [13].
• However, despite the inhibitory influence of localised hypoxia on chromaffin cell responsiveness previously demonstrated in situ, the increase in plasma catecholamine levels after intra-arterial injection of nicotine was significantly enhanced in the hypoxic fish [14].
• Ventricular fibrillation subsequent to ventricular extrasystoles immediately after intra-arterial injection of absolute ethanol at doses of more than 0.18 ml/kg occurred in three [15].
• Two hours after the intravenous injection of 1 mug of estradiol-17beta per kilogram of body weight, incorporation of [3H]-uridine into RNA was two- to threefold higher (2.7 plus or minus 0.4 S.E.M.) in the control horn than the uterine horn that had received an intra-arterial injection of actinomycin D [16].

Biological context of Injections, Intra-Arterial

• Here we report that by employing the above-described strategy, high-level heterologous reporter gene expression was achievable in hindlimb muscles of normal rats as well as dystrophic (mdx) mice (genetic homolog of DMD) after a single intraarterial injection of AdV [17].
• Cerebral blood flow was recorded in 39 patients undergoing cardiac surgery by intraarterial injection of xenon 133 [18].
• Vein graft ultrasonic transit time Q and delta P (from proximal to distal anastomosis) were measured at baseline and after maximal peripheral vasodilatation with an intraarterial injection of papaverine 30 mg [19].
• Decreased vascular resistance after intra-arterial injection of [met]enkephalin in the hindquarters of conscious rabbits [20].
• The functional significance of dopamine release was shown by the increased release of dopamine following an increase in blood pressure obtained by an intraarterial injection of blood [21].

Anatomical context of Injections, Intra-Arterial

• Excitation of receptors in the gastrocnemius muscle by intra-arterial injection of chemicals (NaCl, KCl, and bradykinin) increased firing rates of most (84%, 74%, and 80%, respectively) neurosecretary neurons [22].
• In dogs, intraarterial injection of Sotradecol 3% into the proximally occluded renal, hepatic, splenic, and deep femoral arteries produced arterial occlusion and tissue destruction [23].
• The lack of any substantial excitation of spinothalamic neurones by intra-arterial injections of succinylcholine suggests that these group I actions may have been due to group Ib afferents from Golgi tendon organs [24].
• 2. Small intra-arterial injections of bradykinin (0.2 microgram) and a substantial range of capsaicin doses (2-200 micrograms) consistently activated C polymodal nociceptors without exciting other types of C- or A-fibre cutaneous sense organs [25].
• These increases in diameter were markedly reduced by intra-arterial injection of atropine or by cutting the sciatic nerve, but not by phentolamine and propranolol given together [26].

Associations of Injections, Intra-Arterial with chemical compounds

• Intraarterial injections of vasopressin, in doses ranging logarithmically from 5 X 10(-5) to 5 X 10(-2) U kg-1, caused dose-dependent decreases in flow [27].
• The response to capsaicin was completely abolished by a previous intraluminal application of the local anesthetic lidocaine, and was inhibited by an intraarterial injection of somatostatin [28].
• The technique involves comparison of selective magnification renal arteriograms before and after intra-arterial injection of epinephrine or acetylcholine, seeking changes in direction of flow in potential collateral routes [29].
• The analogs were screened for dopamine-agonist action by intra-arterial injections into the renal vascular bed and for beta2-adrenergic activity by similar injections into the femoral vascular bed in dogs pretreated with phenoxybenzamine [30].
• In response to intra-arterial injections of norepinephrine, hypertensive pigs (n = 8) demonstrated shifts in the dose-response curves to the left and lower vasoconstrictor thresholds than controls (n = 10) [31].

Gene context of Injections, Intra-Arterial

• Intra-arterial injection of 1 nmol IRL 1620 caused an enhanced reduction in pulmonary conductance compared with 1 nmol endothelin (ET-1) or 0.33 nmol IRL 1620 [32].
• Endothelin-1 or endothelin-3 (5 to 200 pmol/kg) was administered by close intra-arterial injection [33].
• Animals were then divided into four groups of 10 each to receive seven daily intraarterial injections of IFN-gamma 100,000 IU/rat/day (HAL + IFN group), TNF-alpha 30 micrograms/rat/day (HAL + TNF group), IFN + TFN (HAL + IFN + TNF group), or normal saline solution (HAL group) [34].
• The intra-arterial injection of 1 microg/kg BW of rGhrelin in ovariectomized goats failed to stimulate GH release, however, a dosage of 3 microg/kg BW significantly increased plasma GH concentrations (P<0.05) [35].
• Following pre-treatment with propranolol (1.0 mg kg-1 i.v.), during on-going chorda-lingual stimulation at 4 Hz, intra-arterial injections of 1 nmol of either vasoactive intestinal peptide (VIP) or pituitary adenylate cyclase activating peptide (PACAP) elicited an increase in the flow and protein output of about the same order of magnitude [36].

Analytical, diagnostic and therapeutic context of Injections, Intra-Arterial

• Under constant flow conditions, intra-arterial injections of phenylephrine and UK14304, alpha 1- and alpha 2-adrenoceptor agonists, increased mesenteric arterial perfusion pressure in a dose-related manner [37].
• The blood flow was measured by the intra-arterial injection of xenon 133 (133Xe), and the isotope clearance was recorded by a multidetector scintillation camera with 254 detectors [38].
• Fourteen patients with hepatocellular carcinoma (HCC) were examined with computed tomography (CT) during arterial portography (CTAP) and with CT after intraarterial injection of iodized oil [39].
• 5 The labelled drug was localized by autoradiography of frozen sections of leg muscles following intra-arterial injection of decamethonium [40].
• We evaluated the effect of ovariectomy and oestradiol benzoate (50 micrograms kg-1 every two days for two weeks) on the vasodepressor response to intra-arterial injection of bradykinin (150-900 ng kg-1) and on the expression of bradykinin B2-receptors [41].

References