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MeSH Review

Evodia

 
 
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Disease relevance of Evodia

 

High impact information on Evodia

  • Evodiamine, an alkaloidal component extracted from the fruit of Evodiae fructus (Evodia rutaecarpa Benth., Rutaceae), exhibits antiproliferative, antimetastatic, and apoptotic activities through a poorly defined mechanism [6].
  • Rutaecarpine is the main active alkaloid of the herbal medicine, Evodia rutaecarpa [7].
  • New indole N-oxide alkaloids from Evodia fargesii [8].
  • The cell to medium ratio of [3H]digoxin accumulation increased significantly in the presence of the decoction of Evodiae fructus, Aurantii nobilis pericarpium, and Zanthoxyli fructus, and the ethyl acetate fraction of all citrus herbs used [9].
  • The caffeine level was significantly decreased by the pretreatment of rutaecarpine, the extract of Evodia rutaecarpa and herbal preparation Wu-Chu-Yu-Tang [10].
 

Chemical compound and disease context of Evodia

 

Biological context of Evodia

 

Anatomical context of Evodia

 

Associations of Evodia with chemical compounds

 

Gene context of Evodia

 

Analytical, diagnostic and therapeutic context of Evodia

References

  1. Protective effects of evodiamine on myocardial ischemia-reperfusion injury in rats. Rang, W.Q., Du, Y.H., Hu, C.P., Ye, F., Xu, K.P., Peng, J., Deng, H.W., Li, Y.J. Planta Med. (2004) [Pubmed]
  2. Anti-inflammatory activity in skin by biomimetic of Evodia rutaecarpa extract from traditional Chinese medicine. Yarosh, D.B., Galvin, J.W., Nay, S.L., Peña, A.V., Canning, M.T., Brown, D.A. J. Dermatol. Sci. (2006) [Pubmed]
  3. HIV inhibitory natural products. 26. Quinoline alkaloids from Euodia roxburghiana. McCormick, J.L., McKee, T.C., Cardellina, J.H., Boyd, M.R. J. Nat. Prod. (1996) [Pubmed]
  4. Antianoxic action and active constituents of evodiae fructus. Yamahara, J., Yamada, T., Kitani, T., Naitoh, Y., Fujimura, H. Chem. Pharm. Bull. (1989) [Pubmed]
  5. Anti-diarrheal effect of water extract of Evodiae fructus in mice. Yu, L.L., Liao, J.F., Chen, C.F. Journal of ethnopharmacology. (2000) [Pubmed]
  6. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion. Takada, Y., Kobayashi, Y., Aggarwal, B.B. J. Biol. Chem. (2005) [Pubmed]
  7. Oxidative metabolism of the alkaloid rutaecarpine by human cytochrome p450. Ueng, Y.F., Don, M.J., Jan, W.C., Wang, S.Y., Ho, L.K., Chen, C.F. Drug Metab. Dispos. (2006) [Pubmed]
  8. New indole N-oxide alkaloids from Evodia fargesii. Qu, S.J., Liu, Q.W., Tan, C.H., Jiang, S.H., Zhu, D.Y. Planta Med. (2006) [Pubmed]
  9. Inhibition of P-glycoprotein-mediated transport by extracts of and monoterpenoids contained in Zanthoxyli fructus. Yoshida, N., Takagi, A., Kitazawa, H., Kawakami, J., Adachi, I. Toxicol. Appl. Pharmacol. (2005) [Pubmed]
  10. Effects of Evodia rutaecarpa and rutaecarpine on the pharmacokinetics of caffeine in rats. Tsai, T.H., Chang, C.H., Lin, L.C. Planta Med. (2005) [Pubmed]
  11. Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Sheu, J.R., Hung, W.C., Lee, Y.M., Yen, M.H. Eur. J. Pharmacol. (1996) [Pubmed]
  12. Induction of mitotic arrest and apoptosis by evodiamine in human leukemic T-lymphocytes. Huang, Y.C., Guh, J.H., Teng, C.M. Life Sci. (2004) [Pubmed]
  13. Alteration of the pharmacokinetics of theophylline by rutaecarpine, an alkaloid of the medicinal herb Evodia rutaecarpa, in rats. Ueng, Y.F., Tsai, T.H., Don, M.J., Chen, R.M., Chen, T.L. J. Pharm. Pharmacol. (2005) [Pubmed]
  14. Pharmacological properties of galenical preparation. XIV. Body temperature retaining effect of the Chinese traditional medicine, "goshuyu-to" and component crude drugs. Kano, Y., Zong, Q.N., Komatsu, K. Chem. Pharm. Bull. (1991) [Pubmed]
  15. Cyclic adenosine monophosphate inhibits quinolone alkaloid evocarpine-induced apoptosis via activation of protein kinase A in human leukaemic HL-60 cells. Kim, N.Y., Pae, H.O., Kang, T.H., Kim, Y.C., Lee, H.S., Chung, H.T. Pharmacol. Toxicol. (2000) [Pubmed]
  16. Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa. Adams, M., Kunert, O., Haslinger, E., Bauer, R. Planta Med. (2004) [Pubmed]
  17. In vitro relaxation of rabbit and human internal anal sphincter by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Jiang, J.K., Chiu, J.H., Yu, I.T., Lin, J.K. Life Sci. (2000) [Pubmed]
  18. Comparative study of the vasodilatory effects of three quinazoline alkaloids isolated from Evodia rutaecarpa. Chiou, W.F., Liao, J.F., Chen, C.F. J. Nat. Prod. (1996) [Pubmed]
  19. Antithrombotic effect of rutaecarpine, an alkaloid isolated from Evodia rutaecarpa, on platelet plug formation in in vivo experiments. Sheu, J.R., Hung, W.C., Wu, C.H., Lee, Y.M., Yen, M.H. Br. J. Haematol. (2000) [Pubmed]
  20. The vasorelaxant effect of evocarpine in isolated aortic strips: mode of action. Yamahara, J., Kobayashi, G., Matsuda, H., Fujimura, H. Eur. J. Pharmacol. (1988) [Pubmed]
  21. Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist. Kobayashi, Y., Nakano, Y., Kizaki, M., Hoshikuma, K., Yokoo, Y., Kamiya, T. Planta Med. (2001) [Pubmed]
  22. Atanine (3-dimethylallyl-4-methoxy-2-quinolone), an alkaloid with anthelmintic activity from the Chinese medicinal plant, Evodia rutaecarpa. Perrett, S., Whitfield, P.J. Planta Med. (1995) [Pubmed]
  23. Pharmacological properties of galenical preparation. XV. Pharmacokinetics study of evocarpine and its metabolite in rats. Kano, Y., Chen, X.F., Kanemaki, S., Zong, Q., Komatsu, K. Chem. Pharm. Bull. (1991) [Pubmed]
  24. A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa. Moon, T.C., Murakami, M., Kudo, I., Son, K.H., Kim, H.P., Kang, S.S., Chang, H.W. Inflamm. Res. (1999) [Pubmed]
  25. Mechanism-based inactivation of human liver microsomal CYP3A4 by rutaecarpine and limonin from Evodia fruit extract. Iwata, H., Tezuka, Y., Kadota, S., Hiratsuka, A., Watabe, T. Drug Metab. Pharmacokinet. (2005) [Pubmed]
  26. The effect of "chi-han (hot nature)" Chinese herbs on the secretion of IL-1 beta and TNF-alpha by mononuclear cells. Chang, J.Y., Yang, T.Y., Chang, C.P., Chang, J.G. The Kaohsiung journal of medical sciences. (1996) [Pubmed]
  27. Induction of cytochrome P450-dependent monooxygenase in mouse liver and kidney by rutaecarpine, an alkaloid of the herbal drug Evodia rutaecarpa. Ueng, Y.F., Wang, J.J., Lin, L.C., Park, S.S., Chen, C.F. Life Sci. (2001) [Pubmed]
  28. Effect of Evodiae fructus extracts on gene expressions related with alcohol metabolism and antioxidation in ethanol-loaded mice. Cho, M.H., Shim, S.M., Lee, S.R., Mar, W., Kim, G.H. Food Chem. Toxicol. (2005) [Pubmed]
  29. The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes. Ueng, Y.F., Jan, W.C., Lin, L.C., Chen, T.L., Guengerich, F.P., Chen, C.F. Drug Metab. Dispos. (2002) [Pubmed]
 
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