Disease relevance of Embryonic and Fetal Development

• This immunoassay is useful for the study of epsilon globin ontogeny during embryonic and fetal development as well as for searching for inappropriate epsilon globin chain expression in hematologic disorders resulting from genetic abnormalities or neoplastic processes [1].
• fgf3 has been implicated in the embryonic and fetal development of the mouse and as an oncogene in murine breast cancer [2].

Psychiatry related information on Embryonic and Fetal Development

• No maternal, embryo or fetotoxicity or teratogenicity was associated with exposure of mice, during critical periods of embryo and fetal development, to 250 ppm of methyl chloride [3].

High impact information on Embryonic and Fetal Development

• However, no detailed analysis is yet available concerning the normal expression of c-fos during embryonic and fetal development [4].
• We report the expression pattern of Scrb1 during embryonic and fetal development, and show that Scrb1 expression closely mirrors the phenotypic defects observed in Crc/Crc mutants [5].
• The wild-type H beta 58 gene encodes a single 2.7 kb mRNA during embryonic and fetal development, and in many adult somatic tissues [6].
• This study reports the structure of the mouse homeobox-containing gene Hox-1.4 of the HOX-1 cluster, as well as its expression pattern during embryonic and fetal development [7].
• The expression of survivin in embryonic and fetal development was investigated [8].

Biological context of Embryonic and Fetal Development

• A central feature of embryonic and fetal development is widespread cell division; folate is central because of its role in nucleic acid synthesis [9].
• These results suggest that temporal regulation of transcription at the MLC1F/3F locus is controlled by separate enhancers which are differentially activated during embryonic and fetal development [10].
• In this study of the embryonic and fetal development of Dbf animals, we focus on the morphogenesis of the limbs and head, and discuss the possible molecular developmental mechanisms [11].
• Vitamin A is required throughout the life cycle, including crucial stages of embryonic and fetal development [12].

Anatomical context of Embryonic and Fetal Development

• ADA is enriched in trophoblast cells of the chorioallantoic placenta and is essential for embryonic and fetal development [13].
• Differentiation of MSH-, ACTH-, endorphin-, and LPH-containing cells in the hypophysis during embryonic and fetal development [14].
• In the present work, by using indirect immunoperoxidase staining, we demonstrate that an immunoreactive vitamin D-binding protein (DBP) is present in this yolk sac throughout embryonic and fetal development [15].
• The hybrid ICM was shown to be capable of contributing to normal embryonic and fetal development after injection into an ovine blastocyst but may be less likely to be incorporated with the ovine host ICM than is the caprine ICM [16].

Associations of Embryonic and Fetal Development with chemical compounds

• Retinoic acid receptors are present in all parts of the cranial region and delivery of retinoids is exquisitely controlled throughout embryonic and fetal development [17].
• Influence of symmetrical polychlorinated biphenyl isomers on embryo and fetal development in mice. I. Teratogenicity of 3, 3', 4, 4', 5, 5',-hexachlorobiphenyl [18].
• Genital and nongenital teratogenesis of prenatal progestogen therapy: the effects of 17 alpha-hydroxyprogesterone caproate on embryonic and fetal development and endochondral ossification in the C57B1/6J mouse [19].
• Although some indications exist that antimony trioxide could interfere with embryonic and fetal development, the studies seem not entirely conclusive [20].
• A fetuin-related glycoprotein (alpha 2HS) in human embryonic and fetal development [21].

Gene context of Embryonic and Fetal Development

• We describe the genomic organization of mouse and human Igsf8, and reveal a dynamic expression pattern during embryonic and fetal development [22].
• The role of growth hormone (GH) and the related placental lactogens in implantation and subsequent embryonic and fetal development is an enigma [23].
• METHODS: In order to understand the role of COX-2 throughout pregnancy, we characterized the cell type and the temporal expression of inducible COX-2 throughout embryonic and fetal development in the rat (n = 22) by immunohistochemistry and in situ hybridization [24].
• The elucidation of the tissue-specific profile of expression of the prolactin (PRL) and growth hormone (GH) receptors during embryonic and fetal development in a range of species has provided a new impetus for the delineation of the specific roles of the hormone ligands for these receptors in development [25].
• The extracellular matrix protein tenascin (TN) is expressed with precise temporo-spatial patterns during embryonic and fetal development and is induced in healing wounds, inflammatory lesions and solid tumors [26].

Analytical, diagnostic and therapeutic context of Embryonic and Fetal Development

• We investigated the temporal and spatial distribution of osteonectin during human embryonic and fetal development, using in situ hybridization and immunohistochemistry [27].

References