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Gene Review

Hmbox1  -  homeobox containing 1

Mus musculus

Synonyms: AI451877, AI604847, F830020C16Rik, Homeobox-containing protein 1
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Disease relevance of Hmbox1


High impact information on Hmbox1


Biological context of Hmbox1


Anatomical context of Hmbox1


Associations of Hmbox1 with chemical compounds


Physical interactions of Hmbox1


Other interactions of Hmbox1


Analytical, diagnostic and therapeutic context of Hmbox1


  1. Homeobox-containing genes in teratocarcinoma embryoid bodies: a possible role for Hox-D12 (Hox-4.7) in establishing the extraembryonic endoderm lineage in the mouse. Labosky, P.A., Weir, M.P., Grabel, L.B. Dev. Biol. (1993) [Pubmed]
  2. Structural abnormalities associated with congenital megacolon in transgenic mice that overexpress the Hoxa-4 gene. Tennyson, V.M., Gershon, M.D., Sherman, D.L., Behringer, R.R., Raz, R., Crotty, D.A., Wolgemuth, D.J. Dev. Dyn. (1993) [Pubmed]
  3. Dlx5 induces expression of COL1A1 promoter contained in a retrovirus vector. Tadić, T., Erceg, I., Stover, M.L., Rowe, D.W., Lichtler, A.C. Croat. Med. J. (2001) [Pubmed]
  4. Pitx2 participates in the late phase of the pathway controlling left-right asymmetry. Piedra, M.E., Icardo, J.M., Albajar, M., Rodriguez-Rey, J.C., Ros, M.A. Cell (1998) [Pubmed]
  5. Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox-1.1 in transgenic mice. Balling, R., Mutter, G., Gruss, P., Kessel, M. Cell (1989) [Pubmed]
  6. Expression of Hox-7.1 in myoblasts inhibits terminal differentiation and induces cell transformation. Song, K., Wang, Y., Sassoon, D. Nature (1992) [Pubmed]
  7. Hox genes specify vertebral types in the presomitic mesoderm. Carapuço, M., Nóvoa, A., Bobola, N., Mallo, M. Genes Dev. (2005) [Pubmed]
  8. Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system. Hallonet, M., Hollemann, T., Pieler, T., Gruss, P. Genes Dev. (1999) [Pubmed]
  9. Primary structure and developmental expression pattern of Hox 3.1, a member of the murine Hox 3 homeobox gene cluster. Breier, G., Dressler, G.R., Gruss, P. EMBO J. (1988) [Pubmed]
  10. Abundant expression of homeobox genes in mouse embryonal carcinoma cells correlates with chemically induced differentiation. Deschamps, J., de Laaf, R., Joosen, L., Meijlink, F., Destrée, O. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  11. Activation of the cytotactin promoter by the homeobox-containing gene Evx-1. Jones, F.S., Chalepakis, G., Gruss, P., Edelman, G.M. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  12. The expression of rat homeobox-containing genes is developmentally regulated and tissue specific. Falzon, M., Chung, S.Y. Development (1988) [Pubmed]
  13. The mouse Hox-1.4 gene: primary structure, evidence for promoter activity and expression during development. Galliot, B., Dollé, P., Vigneron, M., Featherstone, M.S., Baron, A., Duboule, D. Development (1989) [Pubmed]
  14. Isolation and functional analysis of human HMBOX1, a homeobox containing protein with transcriptional repressor activity. Chen, S., Saiyin, H., Zeng, X., Xi, J., Liu, X., Li, X., Yu, L. Cytogenet. Genome Res. (2006) [Pubmed]
  15. Gtx: a novel murine homeobox-containing gene, expressed specifically in glial cells of the brain and germ cells of testis, has a transcriptional repressor activity in vitro for a serum-inducible promoter. Komuro, I., Schalling, M., Jahn, L., Bodmer, R., Jenkins, N.A., Copeland, N.G., Izumo, S. EMBO J. (1993) [Pubmed]
  16. Homeotic transformation of cervical vertebrae in Hoxa-4 mutant mice. Horan, G.S., Wu, K., Wolgemuth, D.J., Behringer, R.R. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  17. Differential expression of the mouse homeobox-containing gene Hox-1.4 during male germ cell differentiation and embryonic development. Wolgemuth, D.J., Viviano, C.M., Gizang-Ginsberg, E., Frohman, M.A., Joyner, A.L., Martin, G.R. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  18. Embryonic expression of the Gax homeodomain protein in cardiac, smooth, and skeletal muscle. Skopicki, H.A., Lyons, G.E., Schatteman, G., Smith, R.C., Andrés, V., Schirm, S., Isner, J., Walsh, K. Circ. Res. (1997) [Pubmed]
  19. Molecular cloning and characterization of homeo-box-containing genes from Atlantic salmon. Fjose, A., Molven, A., Eiken, H.G. Gene (1988) [Pubmed]
  20. Menin interacts directly with the homeobox-containing protein Pem. Lemmens, I.H., Forsberg, L., Pannett, A.A., Meyen, E., Piehl, F., Turner, J.J., Van de Ven, W.J., Thakker, R.V., Larsson, C., Kas, K. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
  21. The segment-specific gene Krox-20 encodes a transcription factor with binding sites in the promoter region of the Hox-1.4 gene. Chavrier, P., Vesque, C., Galliot, B., Vigneron, M., Dollé, P., Duboule, D., Charnay, P. EMBO J. (1990) [Pubmed]
  22. Analysis of Msx1; Msx2 double mutants reveals multiple roles for Msx genes in limb development. Lallemand, Y., Nicola, M.A., Ramos, C., Bach, A., Cloment, C.S., Robert, B. Development (2005) [Pubmed]
  23. The role of Engrailed in establishing the dorsoventral axis of the chick limb. Logan, C., Hornbruch, A., Campbell, I., Lumsden, A. Development (1997) [Pubmed]
  24. The homeobox containing gene Lbx1 is required for correct dorsal-ventral patterning of the neural tube. Krüger, M., Schäfer, K., Braun, T. J. Neurochem. (2002) [Pubmed]
  25. The transcription factor Six2 activates expression of the Gdnf gene as well as its own promoter. Brodbeck, S., Besenbeck, B., Englert, C. Mech. Dev. (2004) [Pubmed]
  26. Dominant hemimelia and En-1 on mouse chromosome 1 are not allelic. Higgins, M., Hill, R.E., West, J.D. Genet. Res. (1992) [Pubmed]
  27. Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11. Davis, A.P., Capecchi, M.R. Development (1994) [Pubmed]
  28. Primary structure, developmentally regulated expression and potential duplication of the zebrafish homeobox gene ZF-21. Njølstad, P.R., Molven, A., Hordvik, I., Apold, J., Fjose, A. Nucleic Acids Res. (1988) [Pubmed]
  29. Psx, a novel murine homeobox gene expressed in placenta. Han, Y.J., Park, A.R., Sung, D.Y., Chun, J.Y. Gene (1998) [Pubmed]
  30. Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny. Pineault, N., Helgason, C.D., Lawrence, H.J., Humphries, R.K. Exp. Hematol. (2002) [Pubmed]
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