Disease relevance of Pyloric Stenosis, Hypertrophic

• Dysregulation of NOS activity in autonomic nerves plays a major role in diverse pathophysiological conditions including migraine headache, hypertrophic pyloric stenosis and male impotence [1].
• Using NADPH diaphorase as a marker for neuronal NOS, deficiency of the nitrergic innervation has been shown in isolated tissue from patients with infantile hypertrophic pyloric stenosis, achalasia and Hirschsprung's disease, suggesting that a lack of NO release might be involved in these disorders [2].
• We report a novel mutation in WT1 exon 9 (1214 A>G) resulting in an amino acid change from H to R at codon 405 in a 46 XY female patient who had congenital hypertrophic pyloric stenosis, pseudohermaphroditism masculinus, renal failure, and Wilms tumor, and died at the age of 22 months [3].
• The development of hypertrophic pyloric stenosis in a patient with prostaglandin-induced foveolar hyperplasia [4].
• AIMS: To assess the efficacy of a new regimen of intravenous atropine treatment for infantile hypertrophic pyloric stenosis (IHPS) with special reference to regression of pyloric hypertrophy [5].

High impact information on Pyloric Stenosis, Hypertrophic

• Nitric oxide synthesis in infantile hypertrophic pyloric stenosis [6].
• Since neuronal nitric oxide synthase and NADPH diaphorase are identical, we used the NADPH diaphorase histochemical reaction to study the distribution of nitric oxide synthase in pyloric tissue from patients with infantile hypertrophic pyloric stenosis [7].
• Abnormalities of glucose tolerance as a late consequence of hypertrophic pyloric stenosis surgically treated in the neonate [8].
• The results from this study suggest a relationship between gastrin and idiopathic hypertrophic pyloric stenosis [9].
• Several experimental studies have been reported within the past few years describing the production of hypertrophic pyloric stenosis in the offspring of dogs injected with pentagastrin during pregnancy [10].

Chemical compound and disease context of Pyloric Stenosis, Hypertrophic

• The association of erythromycin and infantile hypertrophic pyloric stenosis: causal or coincidental [11]?
• Fifty infants with infantile hypertrophic pyloric stenosis were studied prospectively to evaluate the reliability of plasma chloride estimation in the assessment of the acid-base status on admission and during correction of alkalaemia [12].
• Automated pharmacy profiles were examined to determine whether an association between maternal Bendectin use in the first trimester and infantile hypertrophic pyloric stenosis existed [13].
• Some infants with hypertrophic pyloric stenosis (HPS) have responded to oral atropine treatment [14].
• Management and ultrasonographic appearance of infantile hypertrophic pyloric stenosis with intravenous atropine sulfate [14].

Biological context of Pyloric Stenosis, Hypertrophic

• A novel point mutation of the androgen receptor (F804L) in an Egyptian newborn with complete androgen insensitivity associated with congenital glaucoma and hypertrophic pyloric stenosis [15].
• It was found that in infants with hypertrophic pyloric stenosis the rate of p-nitrophenyl propionate hydrolysis was significantly higher than that of the acetate or butyrate [16].

Anatomical context of Pyloric Stenosis, Hypertrophic

• A case report has suggested that exposure to erythromycin through breast milk might cause infantile hypertrophic pyloric stenosis [17].
• The gastric juice and serum levels of PGE2 and F2 alpha have been assayed in nine infants with infantile hypertrophic pyloric stenosis (IHPS) and seven age-matched controls [18].
• Blood serum immunoreactive gastrin level in infants with hypertrophic pyloric stenosis [19].
• Since somatostatin inhibits basal and stimulated gastric acid secretion and gastrin release, it is conceivable that decreased gastric somatostatin concentration may be one of the factors responsible for gastric hypersecretion found in patients who have undergone long-term pylorotomy for hypertrophic pyloric stenosis [20].
• OBJECTIVE: To investigate the immunocolocalization of HO-2 and ICCs in the normal pylorus and in infantile hypertrophic pyloric stenosis (IHPS) [21].

Gene context of Pyloric Stenosis, Hypertrophic

• The aim of this study was to investigate the expression of GDNF and RET in infantile hypertrophic pyloric stenosis (IHPS) [22].
• Gastrin, somatostatin and infantile hypertrophic pyloric stenosis [23].
• Infantile hypertrophic pyloric stenosis and congenital diaphragmatic hernia [24].
• An association of CF with infantile hypertrophic pyloric stenosis (IHPS) has not been previously documented [25].
• Lack of intestinal pacemaker (C-KIT-positive) cells in infantile hypertrophic pyloric stenosis [26].

Analytical, diagnostic and therapeutic context of Pyloric Stenosis, Hypertrophic

• We examined the expression of the neuronal NOS gene at the messenger RNA (mRNA) level in pyloric smooth-muscle biopsy specimens from six patients with infantile hypertrophic pyloric stenosis (IHPS) using a reverse transcription-polymerase chain reaction (RT-PCR) technique [27].

References