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MeSH Review

Hip Fractures

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Disease relevance of Hip Fractures


Psychiatry related information on Hip Fractures


High impact information on Hip Fractures


Chemical compound and disease context of Hip Fractures

  • RESULTS: Women with hip fractures had lower levels of 25-hydroxyvitamin D than women without osteoporosis admitted for elective joint replacement (P = .02) and than women with osteoporosis admitted for elective joint replacement (P = .01) (medians, 32.4, 49.9, and 55.0 nmol/L, respectively; comparisons adjusted for age and estrogen intake) [11].
  • Spontaneous hip fractures in fluoride-treated patients: potential causative factors [12].
  • Two rigorously conducted studies provide credible evidence that the bisphosphonate alendronate reduces the risk of vertebral and hip fractures by approximately 40-50% [13].
  • CONCLUSION: Treatment with risedronate increases bone mineral density and reduces hip fractures in elderly men who are poststroke [2].
  • However, neither raloxifene therapy nor calcitonin therapy reduce the risk of nonvertebral and hip fractures at currently approved doses [14].

Biological context of Hip Fractures


Anatomical context of Hip Fractures


Gene context of Hip Fractures


Analytical, diagnostic and therapeutic context of Hip Fractures


  1. Pathogenesis of bone fragility in women and men. Seeman, E. Lancet (2002) [Pubmed]
  2. Risedronate sodium therapy for prevention of hip fracture in men 65 years or older after stroke. Sato, Y., Iwamoto, J., Kanoko, T., Satoh, K. Arch. Intern. Med. (2005) [Pubmed]
  3. Stress fractures of the lower limbs in osteoporotic patients treated with fluoride. Orcel, P., de Vernejoul, M.C., Prier, A., Miravet, L., Kuntz, D., Kaplan, G. J. Bone Miner. Res. (1990) [Pubmed]
  4. The effect of vitamin D supplementation on vitamin D status and parathyroid function in elderly subjects. Lips, P., Wiersinga, A., van Ginkel, F.C., Jongen, M.J., Netelenbos, J.C., Hackeng, W.H., Delmas, P.D., van der Vijgh, W.J. J. Clin. Endocrinol. Metab. (1988) [Pubmed]
  5. Increased bone fracture prevalence in postmenopausal women suffering from pollen-allergy. Ferencz, V., Meszaros, S., Csupor, E., Toth, E., Bors, K., Falus, A., Horvath, C. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. (2006) [Pubmed]
  6. APOE 4 and hip fracture risk in a community-based study of older adults. Johnston, J.M., Cauley, J.A., Ganguli, M. Journal of the American Geriatrics Society. (1999) [Pubmed]
  7. Fractured neck of femur in black patients: a prospective study. Schnaid, E., MacPhail, A.P., Sweet, M.B. The Journal of bone and joint surgery. British volume. (2000) [Pubmed]
  8. Vitamin D3 and calcium to prevent hip fractures in the elderly women. Chapuy, M.C., Arlot, M.E., Duboeuf, F., Brun, J., Crouzet, B., Arnaud, S., Delmas, P.D., Meunier, P.J. N. Engl. J. Med. (1992) [Pubmed]
  9. Vitamin A intake and hip fractures among postmenopausal women. Feskanich, D., Singh, V., Willett, W.C., Colditz, G.A. JAMA (2002) [Pubmed]
  10. HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients. Wang, P.S., Solomon, D.H., Mogun, H., Avorn, J. JAMA (2000) [Pubmed]
  11. Occult vitamin D deficiency in postmenopausal US women with acute hip fracture. LeBoff, M.S., Kohlmeier, L., Hurwitz, S., Franklin, J., Wright, J., Glowacki, J. JAMA (1999) [Pubmed]
  12. Spontaneous hip fractures in fluoride-treated patients: potential causative factors. Gutteridge, D.H., Price, R.I., Kent, G.N., Prince, R.L., Michell, P.A. J. Bone Miner. Res. (1990) [Pubmed]
  13. Osteoporosis: trials and tribulations. Seeman, E. Am. J. Med. (1997) [Pubmed]
  14. Aging bone and osteoporosis: strategies for preventing fractures in the elderly. Ettinger, M.P. Arch. Intern. Med. (2003) [Pubmed]
  15. Total and free estrogens and androgens in postmenopausal women with hip fractures. Davidson, B.J., Ross, R.K., Paganini-Hill, A., Hammond, G.D., Siiteri, P.K., Judd, H.L. J. Clin. Endocrinol. Metab. (1982) [Pubmed]
  16. Blood conservation in hip trauma. Schmidt, A.H., Templeman, D.C., Kyle, R.F. Clin. Orthop. Relat. Res. (1998) [Pubmed]
  17. Prophylaxis of venous thromboembolism by aspirin, warfarin and heparin in patients with hip fracture. A prospective clinical study with cost-benefit analysis. Alho, A., Stangeland, L., Røttingen, J., Wiig, J.N. Annales chirurgiae et gynaecologiae. (1984) [Pubmed]
  18. Combined lumbar and sacral plexus block compared with plain bupivacaine spinal anesthesia for hip fractures in the elderly. de Visme, V., Picart, F., Le Jouan, R., Legrand, A., Savry, C., Morin, V. Regional anesthesia and pain medicine. (2000) [Pubmed]
  19. Changes in C-reactive protein and erythrocyte sedimentation rate after hip fractures. Ellitsgaard, N., Andersson, A.P., Jensen, K.V., Jorgensen, M. International orthopaedics. (1991) [Pubmed]
  20. Extracellular matrix metalloproteinases around loose total hip prostheses. Takagi, M., Konttinen, Y.T., Santavirta, S., Sorsa, T., Eisen, A.Z., Nordsletten, L., Suda, A. Acta orthopaedica Scandinavica. (1994) [Pubmed]
  21. Increase in serum bone gamma-carboxyglutamic acid protein with aging in women. Implications for the mechanism of age-related bone loss. Delmas, P.D., Stenner, D., Wahner, H.W., Mann, K.G., Riggs, B.L. J. Clin. Invest. (1983) [Pubmed]
  22. Biochemical markers of bone turnover, endogenous hormones and the risk of fractures in postmenopausal women: the OFELY study. Garnero, P., Sornay-Rendu, E., Claustrat, B., Delmas, P.D. J. Bone Miner. Res. (2000) [Pubmed]
  23. Arginine increases insulin-like growth factor-I production and collagen synthesis in osteoblast-like cells. Chevalley, T., Rizzoli, R., Manen, D., Caverzasio, J., Bonjour, J.P. Bone (1998) [Pubmed]
  24. Increased RANKL/OPG mRNA ratio in iliac bone biopsies from women with hip fractures. Abdallah, B.M., Stilgren, L.S., Nissen, N., Kassem, M., Jørgensen, H.R., Abrahamsen, B. Calcif. Tissue Int. (2005) [Pubmed]
  25. Mortality following hip fracture before and after implementation of the prospective payment system. Ray, W.A., Griffin, M.R., Baugh, D.K. Arch. Intern. Med. (1990) [Pubmed]
  26. Use of statins and fracture: results of 4 prospective studies and cumulative meta-analysis of observational studies and controlled trials. Bauer, D.C., Mundy, G.R., Jamal, S.A., Black, D.M., Cauley, J.A., Ensrud, K.E., van der Klift, M., Pols, H.A. Arch. Intern. Med. (2004) [Pubmed]
  27. Structural effects of raloxifene on the proximal femur: results from the multiple outcomes of raloxifene evaluation trial. Uusi-Rasi, K., Beck, T.J., Semanick, L.M., Daphtary, M.M., Crans, G.G., Desaiah, D., Harper, K.D. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. (2006) [Pubmed]
  28. Meta-analysis of the efficacy of alendronate for the prevention of hip fractures in postmenopausal women. Papapoulos, S.E., Quandt, S.A., Liberman, U.A., Hochberg, M.C., Thompson, D.E. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. (2005) [Pubmed]
  29. Surgical repair of hip fractures using continuous spinal anesthesia: comparison of hypobaric solutions of tetracaine and bupivacaine. Van Gessel, E.F., Forster, A., Gamulin, Z. Anesth. Analg. (1989) [Pubmed]
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