Disease relevance of Facial Expression

• OBJECTIVE: Vestibular schwannomas (VSs) affect young patients with Neurofibromatosis 2 (NF-2) and cause very serious problems for hearing, facial expression, and brain stem function [1].
• Bradykinesia, posture, gait, and other midline symptoms, such as speech and facial expression, compared with rigidity, seem to be more closely related to striatal DAT binding [2].
• Infantile spasms: facial expression of affect before and after epilepsy surgery [3].
• RESULTS: With use of the Facial Action Coding System, 4 facial expressions were found to be associated with true myocardial infarction: lowering the brow, pressing the lips, parting the lips, and turning the head left [4].
• In both patients, elevated creatine phosphokinase, a dull facial expression, peripheral edema and slow speech were recognized, and these symptoms were suggestive of hypothyroidism [5].

Psychiatry related information on Facial Expression

• METHODS: Twelve patients with social phobia and 12 healthy control subjects were presented with paired conditioned (CS; neutral facial expressions) and unconditioned stimuli (US; negative odor vs unmanipulated air) [6].
• The aim of this paper is to study the recognition of facial expression of emotions in depressed patients with major depressive disorder (MD) and schizotypal personality disorder (STP) [7].
• Volunteers receiving citalopram detected a higher number of facial expressions of fear and happiness, with reduced response times, relative to those given the placebo [8].
• Compared to healthy subjects, PAF patients were unimpaired on tests of motivational decision-making (Iowa Gambling Task), recognition of emotional facial expressions, Theory of Mind Tasks and tests of social cognition [9].
• Human newborns (birth-6 days) and older infants (14-180 days) were allowed to ingest both urea (0.12-0.24 M) in a mildly sweet diluent and the diluent alone, and multiple measures of responsivity were obtained (relative intake, sucking behavior, and hedonic ratings based on facial expressions and body movements) [10].

High impact information on Facial Expression

• Hoxb1, which is expressed throughout rhombomere 4 (r4), has been shown to be required for the specification of facial branchiomotor neuron progenitors that are programmed to innervate the muscles of facial expression [11].
• Influence of the serotonin transporter promoter gene and shyness on children's cerebral responses to facial expressions [12].
• Increased motivation for work was isolated as a target effect but such symptoms as facial expression, emotional rapport, and psychomotor activity also appeared to be improved by addition of protirelin to the neuroleptics [13].
• The urofacial (Ochoa) syndrome (UFS) is a rare autosomal recessive disease characterized by congenital obstructive uropathy and abnormal facial expression [14].
• Facial emotional expressions were rated with the Facial Action Coding System. The number of facial coverbal gestures (facial expressions that are tied to speech) and the number of words were calculated [15].

Chemical compound and disease context of Facial Expression

• RESULTS: The administration of propranolol, relative to placebo, specifically increased reaction time to identify facial expressions of sadness correctly, in the absence of changes in speed to recognise other facial expressions of emotion [16].

Biological context of Facial Expression

• In ten preterm infants (postconceptional age 27-35 weeks) facial expression and heart rate variability (HRV) were investigated during three situations: (a) the infant at rest in its crib or incubator, (b) provocation of the withdrawal flexor reflex by application of von Frey's hairs, and (c) lancing and squeezing for blood sampling [17].
• In the present study, event-related potentials (ERP) were used to investigate the involvement and temporal dynamics of the frontal and parietal regions in the processing of angry facial expressions [18].

Anatomical context of Facial Expression

• METHODS: The current study assessed the effects of 7 days administration of the selective serotonin reuptake inhibitor (SSRI), citalopram, on amygdala responses to masked presentations of fearful and happy facial expressions in never-depressed volunteers using blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging [19].
• Face and facial expression memory in temporal lobe epilepsy patients: preliminary results [20].
• An objective scaling of facial nerve function based on area analysis (OSCAR) was developed using the variations of luminance produced by changes of facial expression [21].

Associations of Facial Expression with chemical compounds

• RESULTS: In the facial expression recognition task, citalopram and reboxetine reduced the identification of the negative facial expressions of anger and fear [22].
• Analyses of facial expressions revealed that the more fear individuals displayed in response to the stressors, the higher their cardiovascular and cortisol responses to stress [23].
• The addition of rocking to the sucrose condition tended to further blunt the facial expression of pain, but this enhancement did not reach a significant level [24].
• The influence of olanzapine versus risperidone on facial expression of emotions in schizophrenia--preliminary results of a facial electromyogram study [25].
• OBJECTIVE: Therefore the present study examined the effect of an oral beta-blocker (propranolol, 80 mg) upon facial expression recognition in healthy volunteers [16].

Gene context of Facial Expression

• In Task 2, they evaluated target Japanese ideographs (while influenced by preceding positive or negative facial expressions as prime pictures) by pressing "positive" or "negative" buttons [26].
• This study describes an observational system (modified infant pain scale, MIPS) with elements from a previously published observational scale and from assessments of video-recorded infant facial expressions [27].
• Analyses revealed statistical significant reductions in P200 amplitudes for the angry facial expression on both frontal and parietal electrode sites [18].
• When compared to studies of children in the general population, children with ADHD have deficits in their ability to accurately recognize facial expressions of emotion [28].
• Categorical perception of happiness and fear facial expressions: an ERP study [29].

Analytical, diagnostic and therapeutic context of Facial Expression

• Expressivity of facial expression on a visual analog scale in the PPG scored 75.6 +/- 13.3 compared to 51.8 +/- 25.7 in the CG (P < 0.05) [30].
• This is a longitudinal study of facial expression of affect in 28 children with intractable infantile spasms who underwent epilepsy surgery [3].

References