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Chemical Compound Review

benzylacetate     3-phenylpropanoic acid

Synonyms: hydrocinnamate, CHEMBL851, PubChem8185, SureCN3419, AGN-PC-005JV4, ...
 
 
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Disease relevance of Benzylacetic acid

 

High impact information on Benzylacetic acid

 

Chemical compound and disease context of Benzylacetic acid

 

Biological context of Benzylacetic acid

 

Anatomical context of Benzylacetic acid

 

Associations of Benzylacetic acid with other chemical compounds

 

Gene context of Benzylacetic acid

  • Sequence comparisons revealed that while hcaA1A2CD genes encode the four subunits of the 3-phenylpropionate dioxygenase, the hcaB gene codes for the corresponding cis-dihydrodiol dehydrogenase [23].
  • Optically active phenylpropanoic acid derivatives [(S)-5, and (R)-5] were prepared, and their affinities for peroxisome proliferator-activated receptor (PPAR)alpha and PPAR gamma were evaluated [14].
  • Remarkably, the expression of hcaA in the presence of 3-phenylpropionate was sharply and transiently induced at the end of the exponential growth phase [24].
  • The effects of laser fluence on ion formation in MALDI were studied using a tandem TOF mass spectrometer with a Nd-YAG laser and alpha-cyano hydrocinnamic acid matrix [25].
  • PCI was the most effective inhibitor, with a K(i) in the nM region, and no inhibition was shown with 3-phenylpropionic acid [26].
 

Analytical, diagnostic and therapeutic context of Benzylacetic acid

References

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  2. Hepatic beta-oxidation of 3-phenylpropionic acid and the stereospecific dehydration of (R)- and (S)-3-hydroxy-3-phenylpropionyl-CoA by different enoyl-CoA hydratases. Mao, L.F., Chu, C., Schulz, H. Biochemistry (1994) [Pubmed]
  3. Evidence for a gem-Diol Reaction Intermediate in Bacterial C-C Hydrolase Enzymes BphD and MhpC from (13)C NMR Spectroscopy. Li, J.J., Li, C., Blindauer, C.A., Bugg, T.D. Biochemistry (2006) [Pubmed]
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  12. Production and characterization of monoclonal anti-idiotypic antibody exhibiting a catalytic activity similar to carboxypeptidase A. Hu, R., Xie, G.Y., Zhang, X., Guo, Z.Q., Jin, S. J. Biotechnol. (1998) [Pubmed]
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  14. Enantio-dependent binding and transactivation of optically active phenylpropanoic acid derivatives at human peroxisome proliferator-activated receptor alpha. Miyachi, H., Nomura, M., Tanase, T., Suzuki, M., Murakami, K., Awano, K. Bioorg. Med. Chem. Lett. (2002) [Pubmed]
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  23. Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12. Díaz, E., Ferrández, A., García, J.L. J. Bacteriol. (1998) [Pubmed]
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