Chemical Compound Review:
Lopac-A-013 4-(1,3-dimethyl-2,6-dioxo-7H- purin-8...
Synonyms:
CHEMBL8488, A013_SIGMA, AG-A-64642, AG-J-36991, ALBB-009371, ...
- Adenosine-mediated inhibition of platelet aggregation by acadesine. A novel antithrombotic mechanism in vitro and in vivo. Bullough, D.A., Zhang, C., Montag, A., Mullane, K.M., Young, M.A. J. Clin. Invest. (1994)
- Bradykinin mediation of Ca(2+)-activated K+ channels regulates coronary blood flow in ischemic myocardium. Node, K., Kitakaze, M., Kosaka, H., Minamino, T., Hori, M. Circulation (1997)
- Effect of adenosine on atrioventricular conduction. II: Modulation of atrioventricular node transmission by adenosine in hypoxic isolated guinea pig hearts. Clemo, H.F., Belardinelli, L. Circ. Res. (1986)
- Antagonism of the cardiovascular effects of adenosine by caffeine or 8-(p-sulfophenyl)theophylline. Evoniuk, G., von Borstel, R.W., Wurtman, R.J. J. Pharmacol. Exp. Ther. (1987)
- Sites of action of adenosine in interorgan preconditioning of the heart. Liem, D.A., Verdouw, P.D., Ploeg, H., Kazim, S., Duncker, D.J. Am. J. Physiol. Heart Circ. Physiol. (2002)
- Adenosine-induced vasoconstriction in vivo. Role of the mast cell and A3 adenosine receptor. Shepherd, R.K., Linden, J., Duling, B.R. Circ. Res. (1996)
- Electrophysiological and receptor binding studies to assess activation of the cardiac adenosine receptor by adenine nucleotides. Ragazzi, E., Wu, S.N., Shryock, J., Belardinelli, L. Circ. Res. (1991)
- Effects of long-term treatment with the allosteric enhancer, PD81,723, on Chinese hamster ovary cells expressing recombinant human A1 adenosine receptors. Bhattacharya, S., Linden, J. Mol. Pharmacol. (1996)
- A retinal-derived relaxing factor mediates the hypoxic vasodilation of retinal arteries. Delaey, C., Boussery, K., Van de Voorde, J. Invest. Ophthalmol. Vis. Sci. (2000)
- Stimulation of interleukin-6 secretion and gene transcription in primary astrocytes by adenosine. Schwaninger, M., Neher, M., Viegas, E., Schneider, A., Spranger, M. J. Neurochem. (1997)
- Heart/Cardiac Muscle: Modulation of ischaemic contracture in mouse hearts: a 'supraphysiological' response to adenosine. Reichelt, M.E., Willems, L., Peart, J.N., Ashton, K.J., Matherne, G.P., Blackburn, M.R., Headrick, J.P. Exp. Physiol. (2007)
- Adenosine and nitric oxide regulate regional vascular resistance via interdependent and independent mechanisms during sepsis. Sam, A.D., Sharma, A.C., Rice, A.N., Ferguson, J.L., Law, W.R. Crit. Care Med. (2000)
- Pharmacological profile of the novel P2T-purinoceptor antagonist, FPL 67085 in vitro and in the anaesthetized rat in vivo. Humphries, R.G., Tomlinson, W., Clegg, J.A., Ingall, A.H., Kindon, N.D., Leff, P. Br. J. Pharmacol. (1995)
- Effect of adenosine receptor blockade on pial arteriolar dilation during sciatic nerve stimulation. Meno, J.R., Crum, A.V., Winn, H.R. Am. J. Physiol. Heart Circ. Physiol. (2001)
- Role of endothelium in hyperpolarization of coronary smooth muscle by adenosine and its analogues. Olanrewaju, H.A., Hargittai, P.T., Lieberman, E.A., Mustafa, S.J. J. Cardiovasc. Pharmacol. (1995)
- Paeoniflorin reverses guanethidine-induced hypotension via activation of central adenosine A1 receptors in Wistar rats. Cheng, J.T., Wang, C.J., Hsu, F.L. Clin. Exp. Pharmacol. Physiol. (1999)
- Adenosine, a cytoprotective autocoid: effects of adenosine on neutrophil plasma membrane viscosity and chemoattractant receptor display. Cronstein, B.N., Rose, F.R., Pugliese, C. Biochim. Biophys. Acta (1989)
- Hemodynamic effects of adenosine agonists in the conscious spontaneously hypertensive rat. Webb, R.L., McNeal, R.B., Barclay, B.W., Yasay, G.D. J. Pharmacol. Exp. Ther. (1990)
- Investigation of the cellular mechanism of inhibition of formyl-methionyl-leucyl-phenylalanine-induced superoxide anion generation in rat neutrophils by 2-benzyloxybenzaldehyde. Wang, J.P., Chang, L.C., Lin, Y.L., Hsu, M.F., Chang, C.Y., Huang, L.J., Kuo, S.C. Biochem. Pharmacol. (2003)
- NECA-induced hypomotility in mice: evidence for a predominantly central site of action. Durcan, M.J., Morgan, P.F. Pharmacol. Biochem. Behav. (1989)
- Optimal windows of statin use for immediate infarct limitation: 5'-nucleotidase as another downstream molecule of phosphatidylinositol 3-kinase. Sanada, S., Asanuma, H., Minamino, T., Node, K., Takashima, S., Okuda, H., Shinozaki, Y., Ogai, A., Fujita, M., Hirata, A., Kim, J., Asano, Y., Mori, H., Tomoike, H., Kitamura, S., Hori, M., Kitakaze, M. Circulation (2004)
- Inhibition of human monocyte TNF production by adenosine receptor agonists. Le Vraux, V., Chen, Y.L., Masson, I., De Sousa, M., Giroud, J.P., Florentin, I., Chauvelot-Moachon, L. Life Sci. (1993)
- Adenosine receptor blockade reveals N-methyl-D-aspartate receptor- and voltage-sensitive dendritic spikes in rat hippocampal CA1 pyramidal cells in vitro. Li, H., Henry, J.L. Neuroscience (2000)
- Evidence that adenosine mediates the depression of spinal dorsal horn neurons induced by peripheral vibration in the cat. Salter, M.W., Henry, J.L. Neuroscience (1987)
- Protein kinase C-mediated preconditioning of cardiac myocytes: role of adenosine receptor and KATP channel. Liang, B.T. Am. J. Physiol. (1997)
- Attenuation of S-T segment elevation during repetitive coronary occlusions truly reflects the protection of ischemic preconditioning and is not an epiphenomenon. Cohen, M.V., Yang, X.M., Downey, J.M. Basic Res. Cardiol. (1997)