The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Betagan     5-[(2S)-2-hydroxy-3-(tert...

Synonyms: Akbeta, LEVOBUNOLOL, Levobunololum, SureCN24095, CCRIS 4375, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of LEVOBUNOLOL


High impact information on LEVOBUNOLOL


Chemical compound and disease context of LEVOBUNOLOL


Biological context of LEVOBUNOLOL


Anatomical context of LEVOBUNOLOL


Associations of LEVOBUNOLOL with other chemical compounds


Analytical, diagnostic and therapeutic context of LEVOBUNOLOL


  1. Ocular levobunolol. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. Gonzalez, J.P., Clissold, S.P. Drugs (1987) [Pubmed]
  2. Contact dermatitis to levobunolol eyedrops superimposed on IgE-mediated rhinoconjunctivitis. Blumetti, B., Brodell, R.T., Helms, S.E., Brodell, L.P., Bredle, D.L. Ann. Allergy Asthma Immunol. (2006) [Pubmed]
  3. Syncope, bradycardia, and atrioventricular block associated with topical ophthalmic levobunolol. Chun, J.G., Brodsky, M.A., Allen, B.J. Am. Heart J. (1994) [Pubmed]
  4. Allergic contact dermatitis from levobunolol eyedrops. di Lernia, V., Albertini, G., Bisighini, G. Contact Derm. (1995) [Pubmed]
  5. Noninvasive assessment of aqueous humor turnover in the mouse eye. Avila, M.Y., Mitchell, C.H., Stone, R.A., Civan, M.M. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  6. Correlates of acute exercise-induced ocular hypotension. Harris, A., Malinovsky, V., Martin, B. Invest. Ophthalmol. Vis. Sci. (1994) [Pubmed]
  7. Timolol may inhibit aqueous humor secretion by cAMP-independent action on ciliary epithelial cells. McLaughlin, C.W., Peart, D., Purves, R.D., Carré, D.A., Peterson-Yantorno, K., Mitchell, C.H., Macknight, A.D., Civan, M.M. Am. J. Physiol., Cell Physiol. (2001) [Pubmed]
  8. Location of penetration and metabolic barriers to levobunolol in the corneal epithelium of the pigmented rabbit. Ashton, P., Wang, W., Lee, V.H. J. Pharmacol. Exp. Ther. (1991) [Pubmed]
  9. Efficacy and tolerability of 0.5% timolol maleate ophthalmic gel-forming solution QD compared with 0.5% levobunolol hydrochloride BID in patients with open-angle glaucoma or ocular hypertension. Walters, T.R., Maloney, S., Slater, D., Liss, C., Wilson, H., Hartenbaum, D. Clinical therapeutics. (1998) [Pubmed]
  10. Allergic contact dermatitis due to levobunolol with cross-sensitivity to befunolol. Nino, M., Balato, A., Ayala, F., Balato, N. Contact Derm. (2007) [Pubmed]
  11. Comparison of ophthalmic beta-blocking agents. Lesar, T.S. Clinical pharmacy. (1987) [Pubmed]
  12. The effect of levobunolol on aqueous humor dynamics. Yablonski, M.E., Novack, G.D., Burke, P.J., Cook, D.J., Harmon, G. Exp. Eye Res. (1987) [Pubmed]
  13. The effect of azone on ocular levobunolol absorption: calculating the area under the curve and its standard error using tissue sampling compartments. Tang-Liu, D.D., Burke, P.J. Pharm. Res. (1988) [Pubmed]
  14. A clinical evaluation of the effects of topically applied levobunolol and timolol on increased intraocular pressure. Duzman, E., Ober, M., Scharrer, A., Leopold, I.H. Am. J. Ophthalmol. (1982) [Pubmed]
  15. Comparison of concentration-time profiles of levobunolol and timolol in anterior and posterior ocular tissues of albino rabbits. Acheampong, A.A., Breau, A., Shackleton, M., Luo, W., Lam, S., Tang-Liu, D.D. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. (1995) [Pubmed]
  16. Topically applied levobunolol does not cause changes in the corneal endothelium. Fusco, R., Del Prete, A., Gravina, A., Nieto, G. Documenta ophthalmologica. Advances in ophthalmology. (1990) [Pubmed]
  17. The effect of timolol, betaxolol and levobunolol on the surface of rabbit cornea. Follmann, P., Varga, M., Daróczy, J. International ophthalmology. (1989) [Pubmed]
  18. The effect of levobunolol hydrochloride on the calcium and potassium channels in isolated ventricular myocytes of guinea pig. Tang, M., Chen, L., Wei, W., Yang, L., Wang, T., Liu, Z., Hu, X., Sun, H., Luo, H. J. Tongji Med. Univ. (1997) [Pubmed]
  19. Determination of levobunolol and dihydrolevobunolol in blood and urine by high-performance liquid chromatography using fluorescence detection. Hengy, H., Kölle, E.U. J. Chromatogr. (1985) [Pubmed]
  20. Comparison of the ocular beta-blockers. Sorensen, S.J., Abel, S.R. The Annals of pharmacotherapy. (1996) [Pubmed]
  21. Inhibition of endothelin-1 and KCL-induced increase of [CA2+]i by antiglaucoma drugs in cultured A7r5 vascular smooth-muscle cells. Wu, K.Y., Wang, H.Z., Hong, S.J. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. (2004) [Pubmed]
  22. The effect of pilocarpine on ocular levobunolol absorption from ophthalmic solutions. Tang-Liu, D.D., Richman, J.B. Journal of ocular pharmacology. (1994) [Pubmed]
  23. Allergic reactions to brimonidine in patients treated for glaucoma. Blondeau, P., Rousseau, J.A. Can. J. Ophthalmol. (2002) [Pubmed]
  24. Once-daily versus twice-daily levobunolol (0.5%) therapy. A crossover study. Derick, R.J., Robin, A.L., Tielsch, J., Wexler, J.L., Kelley, E.P., Stoecker, J.F., Novack, G.D., Coleman, A.L. Ophthalmology (1992) [Pubmed]
  25. Ocular hypotensive efficacy of 0.25% levobunolol instilled once daily. Wandel, T., Fishman, D., Novack, G.D., Kelley, E., Chen, K.K. Ophthalmology (1988) [Pubmed]
  26. Prophylactic treatment of intraocular pressure elevations after neodymium: YAG laser posterior capsulotomies and extracapsular cataract extractions with levobunolol. Silverstone, D.E., Novack, G.D., Kelley, E.P., Chen, K.S. Ophthalmology (1988) [Pubmed]
WikiGenes - Universities