Chemical Compound Review:
AG-J-43958 1-[(4-morpholin-4-yl-1,2,5- thiadiazol-3...
Synonyms:
SureCN1587691, CHEBI:39465, CCG-205263, KST-1B2826, AC1L1KFQ, ...
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- Pseudomonas exotoxin A prevents beta-adrenoceptor-induced upregulation of Gi protein alpha-subunits and adenylyl cyclase desensitization in rat heart muscle cells. Reithmann, C., Gierschik, P., Müller, U., Werdan, K., Jakobs, K.H. Mol. Pharmacol. (1990)
- Pharmacokinetics and beta-blocking effects of timolol in poor and extensive metabolizers of debrisoquin. McGourty, J.C., Silas, J.H., Fleming, J.J., McBurney, A., Ward, J.W. Clin. Pharmacol. Ther. (1985)
- Effect of beta adrenoceptor antagonists on baroreceptor reflex sensitivity in hypertension. Simon, G., Kiowski, W., Julius, S. Clin. Pharmacol. Ther. (1977)
- Beta-adrenoceptor-mediated inhibition of IFN-gamma, IL-3, and GM-CSF mRNA accumulation in activated human T lymphocytes is solely mediated by the beta2-adrenoceptor subtype. Borger, P., Hoekstra, Y., Esselink, M.T., Postma, D.S., Zaagsma, J., Vellenga, E., Kauffman, H.F. Am. J. Respir. Cell Mol. Biol. (1998)
- Conjunctival proinflammatory and proapoptotic effects of latanoprost and preserved and unpreserved timolol: an ex vivo and in vitro study. Pisella, P.J., Debbasch, C., Hamard, P., Creuzot-Garcher, C., Rat, P., Brignole, F., Baudouin, C. Invest. Ophthalmol. Vis. Sci. (2004)
- Polymorphisms of genes CYP2D6, ADRB1 and GNAS1 in pharmacokinetics and systemic effects of ophthalmic timolol. A pilot study. Nieminen, T., Uusitalo, H., Mäenpää, J., Turjanmaa, V., Rane, A., Lundgren, S., Ropo, A., Rontu, R., Lehtimäki, T., Kähönen, M. Eur. J. Clin. Pharmacol. (2005)
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- Polymorphism of the beta-2 adrenoceptor and IOP lowering potency of topical timolol in healthy subjects. Fuchsjager-Mayrl, G., Markovic, O., Losert, D., Lucas, T., Wachek, V., Muller, M., Schmetterer, L. Mol. Vis. (2005)
- Increased occurrence of left ventricular thrombi during early treatment with timolol in patients with acute myocardial infarction. Johannessen, K.A., Nordrehaug, J.E., von der Lippe, G. Circulation (1987)
- Effect of timolol versus propranolol on hypertension and hemodynamics. Aronow, W.S., Ferlinz, J., Del Vicario, M., Moorthy, K., King, J., Cassidy, J. Circulation (1976)
- Modulation of forebrain electroencephalographic activity in halothane-anesthetized rat via actions of noradrenergic beta-receptors within the medial septal region. Berridge, C.W., Bolen, S.J., Manley, M.S., Foote, S.L. J. Neurosci. (1996)
- Effect of beta-adrenergic blockade with timolol on myocardial blood flow during exercise after myocardial infarction in the dog. Herzog, C.A., Aeppli, D.P., Bache, R.J. J. Am. Coll. Cardiol. (1984)