Chemical Compound Review:
Meloxivet (8E)-8-[hydroxy-[(5-methyl- 1,3-thiazol-2...
Synonyms:
Davies,
Skjodt,
Ziemann,
Schäfer,
Rüdell,
Kahl,
Hirsch-Ernst,
Layton,
Hughes,
Harris,
Shakir,
Ruperto,
Nikishina,
Pachanov,
Shachbazian,
Prieur,
Mouy,
Joos,
Zulian,
Schwarz,
Artamonova,
Emminger,
Bandeira,
Buoncompagni,
Foeldvari,
Falcini,
Baildam,
Kone-Paut,
Alessio,
Gerloni,
Lenhardt,
Martini,
Hanft,
Sigmund,
Simianer,
Stefanovic,
Bosetti,
Silva,
Greenberg,
Bingham,
Abramson,
Reed,
Sebaldt,
Kremer,
Schoenfeld,
Tavares,
Liu,
Kirschenbaum,
Lu,
Yao,
Dosoretz,
Holland,
Levine,
MacDonald,
Morant,
Goldstein,
Burke,
Pettitt,
Cheng,
Lai,
Chiu,
Chem,
Singh,
Lanes,
Triadafilopoulos,
- Ischaemic colitis in a patient taking meloxicam. Garcia, B., Ramaholimihaso, F., Diebold, M.D., Cadiot, G., Thiéfin, G. Lancet (2001)
- A randomized, double-blind clinical trial of two doses of meloxicam compared with naproxen in children with juvenile idiopathic arthritis: short- and long-term efficacy and safety results. Ruperto, N., Nikishina, I., Pachanov, E.D., Shachbazian, Y., Prieur, A.M., Mouy, R., Joos, R., Zulian, F., Schwarz, R., Artamonova, V., Emminger, W., Bandeira, M., Buoncompagni, A., Foeldvari, I., Falcini, F., Baildam, E., Kone-Paut, I., Alessio, M., Gerloni, V., Lenhardt, A., Martini, A., Hanft, G., Sigmund, R., Simianer, S. Arthritis Rheum. (2005)
- Modulatory role of cyclooxygenase-2 in cerebrovascular coupling. Stefanovic, B., Bosetti, F., Silva, A.C. Neuroimage (2006)
- Channelling bias and the incidence of gastrointestinal haemorrhage in users of meloxicam, coxibs, and older, non-specific non-steroidal anti-inflammatory drugs. MacDonald, T.M., Morant, S.V., Goldstein, J.L., Burke, T.A., Pettitt, D. Gut (2003)
- Protective effects of meloxicam on aluminum overload-induced cerebral damage in mice. Jun-Qing, Y., Bei-Zhong, L., Bai-Cheng, H., Qi-Qin, Z. Eur. J. Pharmacol. (2006)
- Cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs inhibit hepatocyte growth factor/scatter factor-induced angiogenesis. Sengupta, S., Sellers, L.A., Cindrova, T., Skepper, J., Gherardi, E., Sasisekharan, R., Fan, T.P. Cancer Res. (2003)
- The cyclooxygenase system participates in functional mdr1b overexpression in primary rat hepatocyte cultures. Ziemann, C., Schäfer, D., Rüdell, G., Kahl, G.F., Hirsch-Ernst, K.I. Hepatology (2002)
- Effect of cardiovascular comorbidities and concomitant aspirin use on selection of cyclooxygenase inhibitor among rheumatologists. Greenberg, J.D., Bingham, C.O., Abramson, S.B., Reed, G., Sebaldt, R.J., Kremer, J. Arthritis Rheum. (2005)
- Meloxicam. Noble, S., Balfour, J.A. Drugs (1996)
- Comparison of the incidence rates of selected gastrointestinal events reported for patients prescribed celecoxib and meloxicam in general practice in England using prescription-event monitoring (PEM) data. Layton, D., Hughes, K., Harris, S., Shakir, S.A. Rheumatology (Oxford, England) (2003)
- Hyperalgesia due to nerve injury: role of prostaglandins. Syriatowicz, J.P., Hu, D., Walker, J.S., Tracey, D.J. Neuroscience (1999)
- A quantitative approach to measure joint pain in experimental osteoarthritis--evidence of a role for nitric oxide. Castro, R.R., Cunha, F.Q., Silva, F.S., Rocha, F.A. Osteoarthr. Cartil. (2006)
- A single-blind, randomized, controlled trial to assess the efficacy and tolerability of rofecoxib, diclofenac sodium, and meloxicam in patients with acute gouty arthritis. Cheng, T.T., Lai, H.M., Chiu, C.K., Chem, Y.C. Clinical therapeutics. (2004)
- Clinical pharmacokinetics of meloxicam. A cyclo-oxygenase-2 preferential nonsteroidal anti-inflammatory drug. Davies, N.M., Skjodt, N.M. Clinical pharmacokinetics. (1999)
- Meloxicam inhibits osteosarcoma growth, invasiveness and metastasis by COX-2-dependent and independent routes. Naruse, T., Nishida, Y., Hosono, K., Ishiguro, N. Carcinogenesis (2006)
- Articular diffusion of meloxicam after a single oral dose: relationship to cyclo-oxygenase inhibition in synovial cells. Lapicque, F., Vergne, P., Jouzeau, J.Y., Loeuille, D., Gillet, P., Vignon, E., Thomas, P., Velicitat, P., Türck, D., Guillaume, C., Gaucher, A., Bertin, P., Netter, P. Clinical pharmacokinetics. (2000)
- Prevention of cytokine-induced changes in leukocyte adhesion receptors by nonsteroidal antiinflammatory drugs from the oxicam family. García-Vicuña, R., Díaz-González, F., González-Alvaro, I., del Pozo, M.A., Mollinedo, F., Cabañas, C., González-Amaro, R., Sánchez-Madrid, F. Arthritis Rheum. (1997)
- Meloxicam inhibits the growth of colorectal cancer cells. Goldman, A.P., Williams, C.S., Sheng, H., Lamps, L.W., Williams, V.P., Pairet, M., Morrow, J.D., DuBois, R.N. Carcinogenesis (1998)
- Effect of the specific cyclooxygenase-2 inhibitor meloxicam on tumour growth and cachexia in a murine model. Hussey, H.J., Tisdale, M.J. Int. J. Cancer (2000)
- Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration. Pop-Busui, R., Marinescu, V., Van Huysen, C., Li, F., Sullivan, K., Greene, D.A., Larkin, D., Stevens, M.J. Diabetes (2002)
- Comparison of inhibitory effects of meloxicam and diclofenac on human thromboxane biosynthesis after single doses and at steady state. Tegeder, I., Lötsch, J., Krebs, S., Muth-Selbach, U., Brune, K., Geisslinger, G. Clin. Pharmacol. Ther. (1999)
- Rofecoxib: a review of its use in the management of osteoarthritis, acute pain and rheumatoid arthritis. Matheson, A.J., Figgitt, D.P. Drugs (2001)
- The effects of meloxicam, indomethacin or NS-398 on eicosanoid synthesis by fresh human gastric mucosa. Tavares, I.A. Aliment. Pharmacol. Ther. (2000)
- Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line. Liu, X.H., Kirschenbaum, A., Lu, M., Yao, S., Dosoretz, A., Holland, J.F., Levine, A.C. J. Biol. Chem. (2002)
- Meloxicam: selective COX-2 inhibition in clinical practice. Furst, D.E. Semin. Arthritis Rheum. (1997)
- Meloxicam: influence on arachidonic acid metabolism. Part II. In vivo findings. Engelhardt, G., Bögel, R., Schnitzler, C., Utzmann, R. Biochem. Pharmacol. (1996)
- Meloxicam inhibits prostaglandin E(2) generation via cyclooxygenase 2 in the inflammatory site but not that via cyclooxygenase 1 in the stomach. Ogino, K., Hatanaka, K., Kawamura, M., Ohno, T., Harada, Y. Pharmacology (2000)
- Risk of serious upper gastrointestinal and cardiovascular thromboembolic complications with meloxicam. Singh, G., Lanes, S., Triadafilopoulos, G. Am. J. Med. (2004)
- Gastrointestinal safety profile of meloxicam: a meta-analysis and systematic review of randomized controlled trials. Schoenfeld, P. Am. J. Med. (1999)
- Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. Lazer, E.S., Miao, C.K., Cywin, C.L., Sorcek, R., Wong, H.C., Meng, Z., Potocki, I., Hoermann, M., Snow, R.J., Tschantz, M.A., Kelly, T.A., McNeil, D.W., Coutts, S.J., Churchill, L., Graham, A.G., David, E., Grob, P.M., Engel, W., Meier, H., Trummlitz, G. J. Med. Chem. (1997)