Chemical Compound Review:
Romurtida (2R)-2-[[(4R)-4-[[(2S)-2- [[(2R)-2-[(3R,4R...
Synonyms:
romurtide, Muroctasin, Romurtidum, Nopia, MDP-lys(L18), ...
- Enhancement of platelet recovery in X-irradiated guinea pigs by romurtide, a synthetic muramyl dipeptide derivative. Namba, K., Otani, T., Osada, Y. Blood (1994)
- Synergistic effects of romurtide and cefmenoxime against experimental Klebsiella pneumonia in mice. Tatara, O., Nakahama, C., Niki, Y. Antimicrob. Agents Chemother. (1992)
- Oral application of romurtide, a synthetic muramyl dipeptide derivative, stimulates nonspecific resistance to microbial infections and hematopoiesis in mice. Namba, K., Nakajima, R., Otani, T., Azuma, I. Vaccine (1996)
- Augmentation by priming with interferon-gamma of the binding of a muramyl dipeptide derivative to macrophages resulting in synergistic macrophage activation. Nagao, S., Sato, K., Osada, Y. Jpn. J. Cancer Res. (1987)
- Effect of MDP-Lys(L18), a derivative of MDP, on enhancing host resistance against Hantaan virus infection in newborn mice. Yoo, Y.C., Yoshimatsu, K., Hatsuse, R., Tamura, M., Yoshida, R., Tono-oka, S., Arikawa, J., Azuma, I. Vaccine (1995)
- Effect of granulocyte-macrophage colony-stimulating factor inducer on left ventricular remodeling after acute myocardial infarction. Maekawa, Y., Anzai, T., Yoshikawa, T., Sugano, Y., Mahara, K., Kohno, T., Takahashi, T., Ogawa, S. J. Am. Coll. Cardiol. (2004)
- Enhancing activity of mycobacterial cell-derived adjuvants on immunogenicity of recombinant human hepatitis B virus vaccine. Koike, Y., Yoo, Y.C., Mitobe, M., Oka, T., Okuma, K., Tono-oka, S., Azuma, I. Vaccine (1998)
- Effect of N alpha-acetylmuramyl-L-alanyl-D-isoglutaminyl-N epsilon-stearoyl- L-lysine on resistance to herpes simplex virus type-1 infection in cyclophosphamide-treated mice. Ishihara, C., Iida, J., Mizukoshi, N., Yamamoto, N., Yamamoto, K., Kato, K., Azuma, I. Vaccine (1989)
- Romurtide, a synthetic muramyl dipeptide derivative, accelerates peripheral platelet recovery in nonhuman primate chemotherapy model. Namba, K., Nitanai, H., Otani, T., Azuma, I. Vaccine (1996)
- Mucosal and systemic immune responses in BALB/c mice to Bacteroides gingivalis fimbriae administered orally. Ogawa, T., Shimauchi, H., Hamada, S. Infect. Immun. (1989)
- Differences in interleukin 1 (IL-1), IL-6, tumor necrosis factor and IL-1 receptor antagonist production by human monocytes stimulated with muramyl dipeptide (MDP) and its stearoyl derivative, romurtide. Suzuki, K., Torii, K., Hida, S., Hayashi, H., Hiyama, Y., Oomoto, Y., Takii, T., Chiba, T., Onozaki, K. Immunopharmacology (1994)
- Romurtide, a synthetic muramyl dipeptide derivative, promotes megakaryocytopoiesis through stimulation of cytokine production in nonhuman primates with myelosuppression. Namba, K., Yamamura, E., Nitanai, H., Otani, T., Azuma, I. Vaccine (1997)
- Synergistic induction of cytotoxicity in macrophages by murine interferon-gamma and biological response modifiers derived from microorganisms. Nagao, S., Sato, K., Osada, Y. Cancer Immunol. Immunother. (1986)
- Beneficial effect of muroctasin on experimental leukopenia induced by cyclophosphamide or irradiation in mice. Nakajima, R., Ishida, Y., Yamaguchi, F., Otani, T., Ono, Y., Nomura, M., Une, T., Osada, Y. Arzneimittel-Forschung. (1988)
- Induction of tumor necrosis factor-alpha in solid tumor region by the orally administered synthetic muramyl dipeptide analogue, romurtide. Ueda, H., Yamazaki, M. Int. Immunopharmacol. (2001)
- Muroctasin [MDP-Lys(18)] augments the production of granulocyte colony-stimulating factor (G-CSF) from human peripheral blood mononuclear cells in vitro. Shimoda, K., Okamura, S., Kawasaki, C., Omori, F., Matsuguchi, T., Niho, Y. Int. J. Immunopharmacol. (1990)
- Stimulation of host-defense mechanism with synthetic adjuvants and recombinant cytokines against viral infection in mice. Azuma, I., Ishihara, C., Iida, J., Yoo, Y.C., Yoshimatsu, K., Arikawa, J. Adv. Exp. Med. Biol. (1992)
- Pharmacological aspects of arthritis induced by a muramyl dipeptide analogue in rats. Sugawara, T., Kato, M., Furuhama, K., Takada, S., Takayama, S. Eur. J. Pharmacol. (1992)
- Review: inducer of cytokines in vivo: overview of field and romurtide experience. Azuma, I. Int. J. Immunopharmacol. (1992)