Chemical Compound Review:
Draflazina 1-[(4-amino-2,6-dichloro...
Synonyms:
Draflazine, Draflazinum, SureCN215826, CHEMBL1628717, KB-216952, ...
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- Molecular cloning and functional characterization of inhibitor-sensitive (mENT1) and inhibitor-resistant (mENT2) equilibrative nucleoside transporters from mouse brain. Kiss, A., Farah, K., Kim, J., Garriock, R.J., Drysdale, T.A., Hammond, J.R. Biochem. J. (2000)
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- Elevated levels of endogenous adenosine alter metabolism and enhance reduction in contractile function during low-flow ischemia: associated changes in expression of Ca(2+)-ATPase and phospholamban. Sommerschild, H.T., Lunde, P.K., Deindl, E., Jynge, P., Ilebekk, A., Kirkebøen, K.A. J. Mol. Cell. Cardiol. (1999)
- The implications of non-linear red blood cell partitioning for the pharmacokinetics and pharmacodynamics of the nucleoside transport inhibitor draflazine. Snoeck, E., Jacqmin, P., Van Peer, A., Danhof, M., Ver Donck, K., Van Belle, H., Woestenborghs, R., Crabbé, R., Van Gool, R., Dupont, A., Heykants, J. British journal of clinical pharmacology. (1996)
- Nucleoside transport inhibition and platelet aggregation in human blood: R75231 and its enantiomers, draflazine and R88016. Beukers, M.W., Kerkhof, C.J., IJzerman, A.P., Soudijn, W. Eur. J. Pharmacol. (1994)
- Studies of the nucleoside transporter inhibitor, draflazine, in the human myocardium. Böhm, M., Weinhold, C., Schwinger, R.H., Müller-Ehmsen, J., Böhm, D., Reichenspurner, H., Reichart, B., Erdmann, E. Br. J. Pharmacol. (1994)
- Population analysis of the non linear red blood cell partitioning and the concentration-effect relationship of draflazine following various infusion rates. Snoeck, E., Piotrovskij, V., Jacqmin, P., Van Peer, A., Danhof, M., Ver Donck, K., Woestenborghs, R., Van Belle, H., Van Bortel, L., Van Gool, R., Dupont, A.G., Heykants, J. British journal of clinical pharmacology. (1997)
- Physiological red blood cell kinetic model to explain the apparent discrepancy between adenosine breakdown inhibition and nucleoside transporter occupancy of draflazine. Snoeck, E., Ver Donck, K., Jacqmin, P., Van Belle, H., Dupont, A.G., Van Peer, A., Danhof, M. J. Pharmacol. Exp. Ther. (1998)
- Interaction of a series of draflazine analogues with equilibrative nucleoside transporters: species differences and transporter subtype selectivity. Hammond, J.R. Naunyn Schmiedebergs Arch. Pharmacol. (2000)
- Protection of canine renal grafts by renin-angiotensin inhibition through nucleoside transport blockade. Booster, M.H., Yin, M., Maessen, J.G., Stubenitsky, B.M., Wijnen, R.M., Kootstra, G. Transpl. Int. (1995)