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MeSH Review

Brachial Artery

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Disease relevance of Brachial Artery


Psychiatry related information on Brachial Artery


High impact information on Brachial Artery

  • Nitrite infusions of 36 and 0.36 micromol/min into the forearm brachial artery resulted in supra- and near-physiologic intravascular nitrite concentrations, respectively, and increased forearm blood flow before and during exercise, with or without NO synthase inhibition [7].
  • MAIN OUTCOME MEASURES: Brachial artery flow-mediated (endothelium-dependent) and glyceryl trinitrate-induced (endothelium-independent) dilatation were compared between previously preeclamptic women and controls [8].
  • Effect of antioxidant vitamins on the transient impairment of endothelium-dependent brachial artery vasoactivity following a single high-fat meal [9].
  • The partial genetic deficiency in TK activity is associated with an inward remodeling of the brachial artery, which is not adapted to a chronic increase in wall shear stress, indicating a new form of arterial dysfunction affecting 5-7% of white people [10].
  • Therefore, L-mono-methyl-arginine to inhibit basal nitric oxide activity, serotonin to stimulate nitric oxide activity, and nitroprusside as endothelium-independent vasodilator were infused in the brachial artery of 13 patients with familial hypercholesterolemia and 13 matched controls [11].

Chemical compound and disease context of Brachial Artery


Biological context of Brachial Artery


Anatomical context of Brachial Artery


Associations of Brachial Artery with chemical compounds

  • After the 4-h sample period, NG-monomethyl-L-arginine (L-NMMA) was infused into the brachial artery for 2 h to bring flow back to baseline and repeat samples were taken (6 h) [27].
  • Unlabeled D-mannitol (a nontransportable molecule) and radioactive 3-O-methyl-D-glucose (the reference molecular probe to assess glucose transport activity) were simultaneously injected into the brachial artery, and the washout curves were measured in the deep venous effluent blood [28].
  • Infusion of NO (36 micromol/min) into the brachial artery increased levels of plasma nitroso species, nitrite, and nitrate in the draining antecubital vein (by < 2-fold, 30-fold, and 4-fold, respectively), indicative of oxidative and nitrosative chemistry [29].
  • In a subgroup of 10 subjects the brachial artery was cannulated to infuse adenosine (0.15, 0.5, 1.5, 5, 15, and 50 micrograms/100 ml forearm per min) before and after intravenous injection of 0.5 mg draflazine [30].
  • Subsequently, isoosmolar CaCl2 solution was infused into the same brachial artery at a rate of 0.09 meq/min, and then, with a 2.5 +/- 0.2-mg/dl increase in ipsilateral venous serum calcium concentrations the incremental responses of both FBF and plasma cyclic GMP to alpha hANP were severely blunted [31].

Gene context of Brachial Artery

  • Big ET-1 was infused into the brachial artery of nine patients with atherosclerosis and nine healthy controls [32].
  • METHODS: On two separate occasions, ADM (1-30 pmol x min(-1)) and PAMP (100-3000 pmol x min(-1)) were infused into the brachial artery of eight male subjects, and forearm blood flow (FBF) assessed using venous occlusion plethysmography [33].
  • METHODS: The selective ET-A receptor blocker BQ-123 (10 and 50 nmol/min) was infused into the brachial artery, alone or in combination with the nitric oxide synthase inhibitor NG-monomethyl-L-arginine acetate (L-NMMA) (2 and 4 micromol/min) in 10 lung transplant recipients without pharmacologically treated hypertension and 8 healthy controls [34].
  • LPL concentration and activity were analyzed, and endothelial function was evaluated noninvasively as flow-mediated dilation of the brachial artery [35].
  • Infusions of PYY into the brachial artery at 5 pmol/min decreased local vasodilation induced by VIP infused at 2 pmol/min at the same site by 40% (P < 0.01), even though this dose of PYY had no significant effect on local blood flow when given alone.(ABSTRACT TRUNCATED AT 250 WORDS)[36]

Analytical, diagnostic and therapeutic context of Brachial Artery


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  10. Arterial and renal consequences of partial genetic deficiency in tissue kallikrein activity in humans. Azizi, M., Boutouyrie, P., Bissery, A., Agharazii, M., Verbeke, F., Stern, N., Bura-Rivière, A., Laurent, S., Alhenc-Gelas, F., Jeunemaitre, X. J. Clin. Invest. (2005) [Pubmed]
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  14. Antihypertensive and renal effects of captopril in relation to renin activity and bradykinin-induced vasodilation. Kiowski, W., van Brummelen, P., Hulthén, L., Amann, F.W., Bühler, F.R. Clin. Pharmacol. Ther. (1982) [Pubmed]
  15. Predictors of endothelial dysfunction in young women with polycystic ovary syndrome. Kravariti, M., Naka, K.K., Kalantaridou, S.N., Kazakos, N., Katsouras, C.S., Makrigiannakis, A., Paraskevaidis, E.A., Chrousos, G.P., Tsatsoulis, A., Michalis, L.K. J. Clin. Endocrinol. Metab. (2005) [Pubmed]
  16. The effect of sildenafil on nitric oxide-mediated vasodilation in healthy men. Dishy, V., Sofowora, G., Harris, P.A., Kandcer, M., Zhan, F., Wood, A.J., Stein, C.M. Clin. Pharmacol. Ther. (2001) [Pubmed]
  17. Epinephrine facilitates neurogenic vasoconstriction in humans. Floras, J.S., Aylward, P.E., Victor, R.G., Mark, A.L., Abboud, F.M. J. Clin. Invest. (1988) [Pubmed]
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  19. Comparative effects of aging in men and women on the properties of the arterial tree. Smulyan, H., Asmar, R.G., Rudnicki, A., London, G.M., Safar, M.E. J. Am. Coll. Cardiol. (2001) [Pubmed]
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  28. Transmembrane glucose transport in skeletal muscle of patients with non-insulin-dependent diabetes. Bonadonna, R.C., Del Prato, S., Saccomani, M.P., Bonora, E., Gulli, G., Ferrannini, E., Bier, D., Cobelli, C., DeFronzo, R.A. J. Clin. Invest. (1993) [Pubmed]
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