Disease relevance of Propene

• Repeated s.c. injection of the four propene oxides induced statistically significant incidences of local tumors, mostly fibrosarcomas [1].
• The soluble methane monooxygenase (sMMO) complex from Methylococcus capsulatus (Bath) catalyses oxygen- and NAD(P)H-dependent oxygenation of methane, propene, and other substrates [2].
• The nitrogenase from wild-type Klebsiella pneumoniae reduces cyclopropene to cyclopropane and propene in the ratio 1:2 at pH 7 [3].
• Propene monooxygenase has been cloned from Mycobacterium sp. strain M156, based on hybridization with the amoABCD genes of Rhodococcus corallinus B276 [4].
• Cloning, expression, and site-directed mutagenesis of the propene monooxygenase genes from Mycobacterium sp. strain M156 [4].

Psychiatry related information on Propene

• Measurements of polymer yield Y versus reaction time t for propene concentrations [M] = 0.15-0.59 mol L(-1) and zirconocene concentrations in the range [Zr] = (2.38-9.52) x 10(-5) mol L(-1) for the borate system showed first-order dependence on [M] and [Zr] [5].

High impact information on Propene

• In addition to these protein-mediated interactions, lipid peroxidation also occurred after H2O2 exposure, as shown by generation of fluorescent amino propene derivatives [6].
• We investigated the adsorption states of 2-methylpropene and propene on Si(100)c(4x2) using low-temperature scanning tunneling microscopy [7].
• In the case of propene oxygenation, the hydroxylation and epoxidation mechanisms are competitive on a dominant quintet spin state surface [8].
• Propene activation by the oxo-iron active species of taurine/alpha-ketoglutarate dioxygenase (TauD) enzyme. How does the catalysis compare to heme-enzymes [8]?
• Subsequent calculations indeed reveal that the gas-phase binding energy of F5PhI to POM-FeO4- is high (ca. 20 kcal/mol) compared to the corresponding binding energy of propene (ca. 2-3 kcal/mol) [9].

Chemical compound and disease context of Propene

• 1,2-Dichloropropane (1,2-D), a widespread groundwater contaminant, can be reductively dechlorinated to propene by anaerobic bacteria [10].
• Rhodococcus corallinus (formerly Nocardia corallina) B-276, isolated with propene as sole carbon and energy source, is able to oxidize trichloroethene (TCE) [11].

Biological context of Propene

• The kinetics of propene polymerization catalyzed by ansa-metallocenes were studied using quenched-flow techniques [5].
• The biomass yield on propene was not affected by the cometabolic degradation of TCE [12].
• The observation that pNC30-deficient strains had lost the ability to grow on propene suggested that the genes of the propene degradation pathway are encoded by the linear plasmid pNC30 [11].
• After hydrolysis of the protein, two diastereomers of N tau-(2-hydroxypropyl)histidine were identified in the hydrolysate from treated animals, suggesting that propene, analogous to ethene, is metabolized to the corresponding epoxide and showing that the oxidation is not stereospecific [13].
• Characterization of Rhodococcus-E. coli shuttle vector pNC9501 constructed from the cryptic plasmid of a propene-degrading bacterium [14].

Anatomical context of Propene

• Among the compounds synthesized, a series of propene derivatives exhibited a potent cytotoxic activity against some tumor cell lines including multidrug resistant cell lines due to the overexpression of P-glycoprotein [15].

Associations of Propene with other chemical compounds

• We estimated, using X-ray photoelectron spectroscopy, that approximately 70% of the 0.11 ML of 2-propen-1-ol that reacts forms propene [16].
• Highly dispersed chromate species on silica catalyse the selective epoxidation of propene to propene oxide (PO) by molecular oxygen under visible light irradiation with the same quantum yield as that under UV light irradiation [17].
• Our earlier observations that sMMO was capable of inserting an oxygen atom from dioxygen into a wide variety of hydrocarbon (and some non-hydrocarbon) substrates has been exploited to either produce value added products (e.g. epoxypropane from propene), or in the bioremediation of pollutants such as chlorinated hydrocarbons [18].
• A theoretical study of the decomposition of triallylphosphine into phosphaacetylene at the B3LYP/6-311++G(3df,2p) level has shown that the most likely mechanism involves two retroene eliminations of propene leading to vinylphosphaacetylene [19].
• Theoretical studies on the ene reaction mechanisms of propene and cyclopropene with ethylene and cyclopropene: concerted or stepwise [20].
• The structure of this new form is similar to those of isotactic polybutene and polystyrene and does not crystallize in polypropylene homopolymer because it would have too low density [21].

Gene context of Propene

• No propene monooxygenase activity was detected with rubrerythrin using the assay designed to test activity of methane monooxygenase component A in the absence of other protein components [22].
• Epoxidation (C=C) vis-à-vis allylic hydroxylation (C-H) reactions of propene with a model compound I (Cpd I) of the enzyme cytochrome P450 were studied using B3LYP density functional theory [23].
• The electroreduction of allyl alcohol to form propene at the platinized platinum electrode in acidic aqueous solution has been studied using CV plots, IR, ESR, and MS spectra, and a semiempricial MO method (MOPAC7/AM1, PM3) [24].
• The potential energy surface for the Cl + propene reaction was analyzed at the MP2 level using Pople's 6-31G(d,p) and 6-311+G(d,p), and Dunning's cc-pVDZ and aug-cc-pVDZ basis sets [25].
• We have investigated a Mars-van Krevelen mechanism that involves stepwise adsorption of the propane at an oxygen site followed by desorption of a water molecule and propene, and subsequent adsorption of an oxygen molecule to complete the catalytic cycle [26].

Analytical, diagnostic and therapeutic context of Propene

• Influence of regio- and stereoregularity of propene insertion on crystallization behavior and elasticity of ethene-propene copolymers [27].
• The mutants were screened for altered stereoselectivity in the propene/epoxypropane reaction by a whole-cell assay, solvent extraction, and chiral gas chromatography analysis protocol that is suitable for scale up to several thousand mutants and that is estimated to detect differences in e.e. of as little as 5% [28].
• To further characterize the deposited PPP, Fourier Transform infrared (FTIR) spectroscopy in the attenuated total reflection (ATR) mode was used [29].
• Southern blot analysis with the alkene monooxygenase revealed positive signals with linear plasmids of two propene-oxidizing Rhodococcus ruber strains [11].
• Male CBA mice were exposed to propene, unlabelled or 14C-labelled, by inhalation, or to 14C-labelled propylene oxide by intraperitoneal injection [30].

References