The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

Polytef     1,1,2,2-tetrafluoroethene

Synonyms: Fluoroplast 4, CHEMBL541730, HSDB 844, CCRIS 7738, LS-580, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Polytef

 

High impact information on Polytef

 

Biological context of Polytef

  • Inhalation of TFE by rats and mice caused slight microscopic changes in the kidneys of rats and mice, but no histopathological changes in the liver [3].
  • An unusual case is presented of a patient who developed a "thyroid" nodule following injection of Polytef into the left posterior vocal cord for impaired phonation [8].
 

Anatomical context of Polytef

 

Associations of Polytef with other chemical compounds

 

Gene context of Polytef

  • Frequency of ras mutations in liver neoplasms from B6C3F1 mice exposed to tetrafluoroethylene for two years [18].
  • Metabolism of the common industrial gas tetrafluoroethylene in mammals results in the formation of S-(1,1,2,2)-tetrafluoroethyl-L-cysteine (TFEC), which can be bioactivated by a mitochondrial C-S lyase commonly referred to as beta-lyase [19].
  • Rats exposed to 50 mg/kg TFE-CYS had a mild anemia, and rats exposed to 1200 ppm TFE had slight, biologically inconsequential decreases in erythrocyte mass that may have been compound-related [3].
  • More recently, two major materials have been developed that seem to be useful in treating stress incontinence by periurethral injection: Polytef paste and GAX collagen [20].
  • In all groups adhesive systems were applied according to manufacturers' instructions and light cured; then a restorative composite resin (TPH Spectrum, Dentsply Ind. Com. LTDA) was placed in a polytef matrix and cured [21].
 

Analytical, diagnostic and therapeutic context of Polytef

  • MATERIALS AND METHODS: Between October 1994 and June 2000, 95 patients with post-radical prostatectomy incontinence underwent bulbourethral sling placement with tetrafluoroethylene bolsters at our hospital [22].
  • Successful thrombolytic therapy for acute and chronic occlusion of polytef vascular grafts [2].
  • Recordings were performed with polytef-insulated guide wires in the course of interventional angiographies in 23 patients [23].
  • Ureterovesical reimplantation after failure of endoscopic treatment of reflux by submucosal injection of polytef paste [24].
  • The patient's management before augmentation with collagen included extended supraglottic laryngectomy, radiation therapy, and Polytef injection [25].

References

  1. Migration and granulomatous reaction after periurethral injection of polytef (Teflon). Malizia, A.A., Reiman, H.M., Myers, R.P., Sande, J.R., Barham, S.S., Benson, R.C., Dewanjee, M.K., Utz, W.J. JAMA (1984) [Pubmed]
  2. Successful thrombolytic therapy for acute and chronic occlusion of polytef vascular grafts. Bisig, C.J., Kerstein, M.D. Archives of surgery (Chicago, Ill. : 1960) (1983) [Pubmed]
  3. Toxicity of tetrafluoroethylene and S-(1,1,2, 2-tetrafluoroethyl)-L-cysteine in rats and mice. Keller, D.A., Kennedy, G.L., Ross, P.E., Kelly, D.P., Elliott, G.S. Toxicol. Sci. (2000) [Pubmed]
  4. Endoscopic correction of primary vesicoureteric reflux by subureteric injection of polytetrafluoroethylene. Puri, P. Lancet (1990) [Pubmed]
  5. Artificial surface effect on red blood cells and platelets in laminar shear flow. Alkhamis, T.M., Beissinger, R.L., Chediak, J.R. Blood (1990) [Pubmed]
  6. Sclerosing thyroid cysts using a polytef intravenous cannula. Tajiri, J., Nomaru, S., Morita, M., Higashi, K., Umeda, T., Sato, T. Arch. Intern. Med. (1986) [Pubmed]
  7. Bioactivation of the cysteine-S-conjugate and mercapturic acid of tetrafluoroethylene to acylating reactive intermediates in the rat: dependence of activation and deactivation activities on acetyl coenzyme A availability. Commandeur, J.N., De Kanter, F.J., Vermeulen, N.P. Mol. Pharmacol. (1989) [Pubmed]
  8. Teflon granuloma mimicking a thyroid tumor. Wilson, R.A., Gartner, W.S. Diagn. Cytopathol. (1987) [Pubmed]
  9. New cell fusion method using polymer membrane. Karube, I., Tamiya, E., Matsuoka, H. FEBS Lett. (1984) [Pubmed]
  10. Polytef (polytetrafluoroethylene) alloplastic grafting as a substitute for mucous membrane. Levin, P.S., Dutton, J.J. Arch. Ophthalmol. (1990) [Pubmed]
  11. Plasma polymerized tetrafluoroethylene/polyethylene terephthalate vascular prostheses. Greisler, H.P., Dennis, J.W., Schwarcz, T.H., Klosak, J.J., Ellinger, J., Kim, D.U. Archives of surgery (Chicago, Ill. : 1960) (1989) [Pubmed]
  12. Intraesophageal Polytef injection for the treatment of reflux esophagitis. Shafik, A. Surgical endoscopy. (1996) [Pubmed]
  13. Staphylococcus epidermidis graft infection is associated with locally suppressed major histocompatibility complex class II and elevated MAC-1 expression. Henke, P.K., Bergamini, T.M., Garrison, J.R., Brittian, K.R., Peyton, J.C., Lam, T.M. Archives of surgery (Chicago, Ill. : 1960) (1997) [Pubmed]
  14. In vivo characterization of the inflammatory properties of poly(tetrafluoroethylene) particulates. Kossovsky, N., Millett, D., Juma, S., Little, N., Briggs, P.C., Raz, S., Berg, E. J. Biomed. Mater. Res. (1991) [Pubmed]
  15. Plasma gas discharge deposited fluorocarbon polymers exhibit reduced elutability of adsorbed albumin and fibrinogen. Bohnert, J.L., Fowler, B.C., Horbett, T.A., Hoffman, A.S. Journal of biomaterials science. Polymer edition. (1990) [Pubmed]
  16. Conformation analysis and molecular mobility of ethylene and tetrafluoroethylene copolymer using solid-state 19F MAS and 1H --> 19F CP/MAS NMR spectroscopy. Aimi, K., Ando, S. Magnetic resonance in chemistry : MRC. (2004) [Pubmed]
  17. The use of silicone/polyurethane graft polymers as a means of eliminating surface cracking of polyurethane prostheses. Pinchuk, L., Martin, J.B., Esquivel, M.C., MacGregor, D.C. Journal of biomaterials applications. (1988) [Pubmed]
  18. Frequency of ras mutations in liver neoplasms from B6C3F1 mice exposed to tetrafluoroethylene for two years. Hong, H.H., Devereux, T.R., Roycroft, J.H., Boorman, G.A., Sills, R.C. Toxicologic pathology. (1998) [Pubmed]
  19. Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine. James, E.A., Gygi, S.P., Adams, M.L., Pierce, R.H., Fausto, N., Aebersold, R.H., Nelson, S.D., Bruschi, S.A. Biochemistry (2002) [Pubmed]
  20. Periurethral injection for the treatment of urinary incontinence. Benshushan, A., Brzezinski, A., Shoshani, O., Rojansky, N. Obstetrical & gynecological survey. (1998) [Pubmed]
  21. Influence of phosphoric acid pretreatment on self-etching bond strengths. Erhardt, M.C., Cavalcante, L.M., Pimenta, L.A. Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] (2004) [Pubmed]
  22. Long-term results of the bulbourethral sling procedure. Stern, J.A., Clemens, J.Q., Tiplitsky, S.I., Matschke, H.M., Jain, P.M., Schaeffer, A.J. J. Urol. (2005) [Pubmed]
  23. Intracranial electroencephalographic and evoked-potential recording from intravascular guide wires. Stoeter, P., Dieterle, L., Meyer, A., Prey, N. AJNR. American journal of neuroradiology. (1995) [Pubmed]
  24. Ureterovesical reimplantation after failure of endoscopic treatment of reflux by submucosal injection of polytef paste. Lacombe, A. Eur. Urol. (1990) [Pubmed]
  25. Persistence of injectable collagen in the human larynx: a histopathologic study. Ford, C.N., Gilchrist, K.W., Bartell, T.E. Laryngoscope (1987) [Pubmed]
 
WikiGenes - Universities