Disease relevance of Licryfilcon A

• Plasmapheresis for rapidly progressive glomerulonephritis: the mystique of dramatic intervention [1].
• Poly(2-hydroxyethyl methacrylate) can precisely vary the shape of cells without toxicity [2].
• In MCF-7 cells IGF-I induced expression of two genes, lasp-1 and mystique, which could contribute to metastasis [3].
• Mystique was highly expressed in metastatic but not in androgen-dependent prostate cancer cell lines and Mystique overexpression in MCF-7 cells promoted cell migration and invasion [3].
• Ultrasonically controlled release of ciprofloxacin from self-assembled coatings on poly(2-hydroxyethyl methacrylate) hydrogels for Pseudomonas aeruginosa biofilm prevention [4].

Psychiatry related information on Licryfilcon A

• These changes have implications for the health care practitioner who is a product of the authority structure of academic and clinical institutions steeped in traditional autonomous and unilateral decision making in the mystique of the medical arena [5].
• Excerpts from The Learning Mystique: a Critical Look at "Learning Disabilities" [6].
• Re: 'The mystique of masochism', Cahiers jungiens de psychanalyse [7].
• Social perceptions of cancer and their impacts: implications for nursing practice arising from the literature At the millennium cancer still holds a special mystique and is imbued with socio-cultural meanings, which extend far beyond the rational, scientific and biological facts of the disease [8].
• Among psychoanalysts of all colorations respecting their Freudian orthodoxy, there is a special mystique and nostalgia around the Oedipus complex and paramountcy of the father in a child's mental life; but Otto Rank took a militant, yet reasoned, stand against such patriarchal biases [9].

High impact information on Licryfilcon A

• Ahch and the feminine mystique [10].
• X chromosome inactivation: the feminine mystique continues [11].
• These cells also exhibited stringent dependency on cell shape with a mitotic index of less than 3% at poly(2-hydroxyethyl methacrylate) concentrations at which the cells were rounded versus a labeling index of 75-90% when the cells were flat [2].
• The human homologue of Mystique is located on chromosome 8p21.2 and encodes a PDZ LIM domain protein (PDLIM2) [12].
• Overexpression of Mystique 2 in MCF-7 cells suppressed colony formation in soft agarose and enhanced cell adhesion to collagen and fibronectin [12].

Chemical compound and disease context of Licryfilcon A

• Embolization using poly(2-hydroxyethyl methacrylate) (PHEMA) hydrogel particles, of cylindrical spherical form, was successfully achieved in 42 children treated for non-operable haemangiomas of the liver, and angiodysplasias [13].
• The greatest daytime corneal edema, 4.7 percent, occurred with the Mystique lens compared with 2.7 percent with CV Classic and 1.8 percent and 1.7 percent with the opaque and clear Durasoft 3 lenses respectively [14].

Biological context of Licryfilcon A

• This pre-mRNA splicing switch was reversible: cells transferred from poly(2-hydroxyethyl methacrylate) back to plastic resumed cell division and down-regulated exon 17B expression [15].
• Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growth [12].
• By comparing differential gene expression in the insulin-like growth factor (IGF)-IR null cell fibroblast cell line (R- cells) with cells overexpressing the IGF-IR (R+ cells), we identified the Mystique gene expressed as alternatively spliced variants [12].
• As a first step toward the design and fabrication of biomimetic bonelike composite materials, we have developed a template-driven nucleation and mineral growth process for the high-affinity integration of hydroxyapatite with a poly(2-hydroxyethyl methacrylate) (pHEMA) hydrogel scaffold [16].
• Shape was controlled independent of serum concentration, anchorage, and cell density by alteration of substratum adhesiveness with poly(2-hydroxyethyl methacrylate) (poly[HEMA]) [17].

Anatomical context of Licryfilcon A

• The data indicate that Mystique is an IGF-IR-regulated adapter protein located at the actin cytoskeleton that is necessary for the migratory capacity of epithelial cells [12].
• Only one isoform of endogenous human Mystique protein, Mystique 2, was detected in cell lines [12].
• These questions and recent work that bears on the mystique of the nuclear matrix are addressed in this essay [18].
• A controlled series of intraocular lens implantations on paired cat eyes was performed to determine if a polymacon sheet (Bausch & Lomb plano-T soft contact lens) could protect the corneal endothelium from damage caused by contact with a methyl methacrylate intraocular lens [19].
• Composite poly(2-hydroxyethyl methacrylate) membranes as rate-controlling barriers for transdermal applications [20].

Associations of Licryfilcon A with other chemical compounds

• We examined the regulation of collagenase production by rabbit keratocyte, epithelial and mixed keratocyte/epithelial cell cultures which were exposed to poly(2-hydroxyethyl methacrylate) (PHEMA) hydrogel surfaces with different chemistries and morphologies (sponge and homogeneous gels) [21].
• A convenient two-step route was developed to prepare new anionic ATRP macroinitiators from near-monodisperse poly(2-hydroxyethyl methacrylate) precursors by partial esterification with 2-bromoisobutyryl bromide, followed by esterification of the remaining hydroxyl groups using excess 2-sulfobenzoic acid cyclic anhydride [22].
• Glucose oxidase was entrapped between poly(2-hydroxyethyl methacrylate) membranes and conditions were optimized for high enzyme activity and high levels of entrapment [23].
• Acute (10 days) and chronic (360 days after implantation) tissue reaction was characterized numerically and compared with poly(2-hydroxyethyl methacrylate), used in the Drug Control Research Institute in Prague as a standard in the evaluation of polymers, for which good tolerance in the clinical practice has been demonstrated [24].
• Model synthetic tendons consisting of 20 vol % of texturized poly(ethylene terephthalate) fibers and of the water-swollen poly(2-hydroxyethyl methacrylate) matrix have the tensile modulus E = 1.5 +/- 0.1 GPa, strength and strain-at-break sigma b = 85 +/- 10 MPa and epsilon b = 0.08 +/- 0.02 [25].

Gene context of Licryfilcon A

• Proteins falling into the reported molecular weight ranges of albumin, PMFA, IgG, IgA (sec), lactoferrin and subunits of protein G were evident on all gels at 1 minute of wear, but these protein groups did not have a detectable increase in deposition after 24 hours wear for either the SeeQuence or the Acuvue lenses [26].
• L-Asparaginase from Escherichia coli was immobilized by entrapment in a gel based on poly(2-hydroxyethyl methacrylate) with an activity as high as 730 I.U./g of dry gel [27].
• The degree of grafting and the mechanical properties of SBS, SBS-g-HEMA, and PHEMA were measured [28].
• The relative amount of alpha-granule membrane glycoprotein (GMP-140) which appears on the cell membrane by activation of platelets on the PMEB surfaces was less than that on poly(BMA) and poly(2-hydroxyethyl methacrylate) [29].
• The glutamine bienzyme sensor was prepared by co-immobilization of glutaminase with glutamate oxidase within a photopatterned poly(2-hydroxyethyl methacrylate) (pHEMA) hydrogel membrane [30].

Analytical, diagnostic and therapeutic context of Licryfilcon A

• Elucidation of the mechanisms of nonresponsiveness (clonal exhaustion-deletion and immune ignorance) and their regulation removed much of the historical mystique of transplantation [31].
• Matters such as rate of intravenous injection, periodicity of administration, dosage, and the monitoring of therapy should not be shrouded in a mystique that is passed on from one generation of house officers to another [32].
• As long as its water content is controlled between 63 and 78%, the contact lens made of poly(methyl methacrylate-N-vinylpyrrolidone) has the flexibility on the same order as that of conventional soft contact lenses of poly(2-hydroxyethyl methacrylate) [33].
• Microspheres of poly(2-hydroxyethyl methacrylate) with and without cross-linker were prepared by suspension polymerization [34].
• In order to assess the effect of gelatin, which is routinely used for ES cell cultures, PHEMA slabs were soaked in gelatin solutions and compared the number of cells on gelatin-treated and untreated slabs 4 days after cell seeding [35].

References