Gene Review:
DCTN2 - dynactin 2 (p50)
Homo sapiens
Synonyms:
50 kDa dynein-associated polypeptide, DCTN-50, DCTN50, DYNAMITIN, Dynactin complex 50 kDa subunit, ...
- Phenotypic changes associated with DYNACTIN-2 (DCTN2) over expression characterise SJSA-1 osteosarcoma cells. Bransfield, K.L., Askham, J.M., Leek, J.P., Robinson, P.A., Mighell, A.J. Mol. Carcinog. (2006)
- Function of dynein and dynactin in herpes simplex virus capsid transport. Döhner, K., Wolfstein, A., Prank, U., Echeverri, C., Dujardin, D., Vallee, R., Sodeik, B. Mol. Biol. Cell (2002)
- Chlamydia trachomatis uses host cell dynein to traffic to the microtubule-organizing center in a p50 dynamitin-independent process. Grieshaber, S.S., Grieshaber, N.A., Hackstadt, T. J. Cell. Sci. (2003)
- Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera. García-Mata, R., Bebök, Z., Sorscher, E.J., Sztul, E.S. J. Cell Biol. (1999)
- p53 is associated with cellular microtubules and is transported to the nucleus by dynein. Giannakakou, P., Sackett, D.L., Ward, Y., Webster, K.R., Blagosklonny, M.V., Fojo, T. Nat. Cell Biol. (2000)
- Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi. Hirose, H., Arasaki, K., Dohmae, N., Takio, K., Hatsuzawa, K., Nagahama, M., Tani, K., Yamamoto, A., Tohyama, M., Tagaya, M. EMBO J. (2004)
- Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function. Tai, C.Y., Dujardin, D.L., Faulkner, N.E., Vallee, R.B. J. Cell Biol. (2002)
- A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization. Helfand, B.T., Mikami, A., Vallee, R.B., Goldman, R.D. J. Cell Biol. (2002)
- Modulation of substrate adhesion dynamics via microtubule targeting requires kinesin-1. Krylyshkina, O., Kaverina, I., Kranewitter, W., Steffen, W., Alonso, M.C., Cross, R.A., Small, J.V. J. Cell Biol. (2002)
- Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix. Kapoor, T.M., Mitchison, T.J. J. Cell Biol. (2001)
- In vivo interaction between dynamitin and MacMARCKS detected by the fluorescent resonance energy transfer method. Jin, T., Yue, L., Li, J. J. Biol. Chem. (2001)
- Dynamitin controls Beta 2 integrin avidity by modulating cytoskeletal constraint on integrin molecules. Jin, T., Li, J. J. Biol. Chem. (2002)
- Protein kinase C-regulated dynamitin-macrophage-enriched myristoylated alanine-rice C kinase substrate interaction is involved in macrophage cell spreading. Yue, L., Lu, S., Garces, J., Jin, T., Li, J. J. Biol. Chem. (2000)
- Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. Burkhardt, J.K., Echeverri, C.J., Nilsson, T., Vallee, R.B. J. Cell Biol. (1997)
- The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain. Berrueta, L., Tirnauer, J.S., Schuyler, S.C., Pellman, D., Bierer, B.E. Curr. Biol. (1999)
- Real time imaging reveals a peroxisomal reticulum in living cells. Schrader, M., King, S.J., Stroh, T.A., Schroer, T.A. J. Cell. Sci. (2000)
- Formation of spindle poles by dynein/dynactin-dependent transport of NuMA. Merdes, A., Heald, R., Samejima, K., Earnshaw, W.C., Cleveland, D.W. J. Cell Biol. (2000)
- RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins. Khanna, H., Hurd, T.W., Lillo, C., Shu, X., Parapuram, S.K., He, S., Akimoto, M., Wright, A.F., Margolis, B., Williams, D.S., Swaroop, A. J. Biol. Chem. (2005)
- Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling. Wang, H., Hu, X., Ding, X., Dou, Z., Yang, Z., Shaw, A.W., Teng, M., Cleveland, D.W., Goldberg, M.L., Niu, L., Yao, X. J. Biol. Chem. (2004)