Gene Review:
Epha1 - Eph receptor A1
Mus musculus
Synonyms:
5730453L17Rik, AL033318, Embryonic stem cell kinase, Eph, Ephrin type-A receptor 1, ...
- Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells. Holland, S.J., Gale, N.W., Gish, G.D., Roth, R.A., Songyang, Z., Cantley, L.C., Henkemeyer, M., Yancopoulos, G.D., Pawson, T. EMBO J. (1997)
- Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo. Brantley, D.M., Cheng, N., Thompson, E.J., Lin, Q., Brekken, R.A., Thorpe, P.E., Muraoka, R.S., Cerretti, D.P., Pozzi, A., Jackson, D., Lin, C., Chen, J. Oncogene (2002)
- The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization. Ogawa, K., Pasqualini, R., Lindberg, R.A., Kain, R., Freeman, A.L., Pasquale, E.B. Oncogene (2000)
- Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis. Nakamoto, M., Bergemann, A.D. Microsc. Res. Tech. (2002)
- Proangiogenic Role of ephrinB1/EphB1 in Basic Fibroblast Growth Factor-Induced Corneal Angiogenesis. Kojima, T., Chang, J.H., Azar, D.T. Am. J. Pathol. (2007)
- Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Foo, S.S., Turner, C.J., Adams, S., Compagni, A., Aubyn, D., Kogata, N., Lindblom, P., Shani, M., Zicha, D., Adams, R.H. Cell (2006)
- EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin. Shamah, S.M., Lin, M.Z., Goldberg, J.L., Estrach, S., Sahin, M., Hu, L., Bazalakova, M., Neve, R.L., Corfas, G., Debant, A., Greenberg, M.E. Cell (2001)
- Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region. Wybenga-Groot, L.E., Baskin, B., Ong, S.H., Tong, J., Pawson, T., Sicheri, F. Cell (2001)
- Embryonic stem cells express multiple Eph-subfamily receptor tyrosine kinases. Lickliter, J.D., Smith, F.M., Olsson, J.E., Mackwell, K.L., Boyd, A.W. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. van Eyll, J.M., Passante, L., Pierreux, C.E., Lemaigre, F.P., Vanderhaeghen, P., Rousseau, G.G. Gene Expr. Patterns (2006)
- Eph receptors and ephrins demarcate cerebellar lobules before and during their formation. Rogers, J.H., Ciossek, T., Menzel, P., Pasquale, E.B. Mech. Dev. (1999)
- Crystal structure of the ligand-binding domain of the receptor tyrosine kinase EphB2. Himanen, J.P., Henkemeyer, M., Nikolov, D.B. Nature (1998)
- Tyrosine phosphorylation of transmembrane ligands for Eph receptors. Brückner, K., Pasquale, E.B., Klein, R. Science (1997)
- Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain. Becker, N., Seitanidou, T., Murphy, P., Mattéi, M.G., Topilko, P., Nieto, M.A., Wilkinson, D.G., Charnay, P., Gilardi-Hebenstreit, P. Mech. Dev. (1994)
- ELK and LERK-2 in developing kidney and microvascular endothelial assembly. Daniel, T.O., Stein, E., Cerretti, D.P., St John, P.L., Robert, B., Abrahamson, D.R. Kidney Int. Suppl. (1996)
- Tiam1 mediates neurite outgrowth induced by ephrin-B1 and EphA2. Tanaka, M., Ohashi, R., Nakamura, R., Shinmura, K., Kamo, T., Sakai, R., Sugimura, H. EMBO J. (2004)
- Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases. Brambilla, R., Schnapp, A., Casagranda, F., Labrador, J.P., Bergemann, A.D., Flanagan, J.G., Pasquale, E.B., Klein, R. EMBO J. (1995)
- Characterization of the Epha1 receptor tyrosine kinase: expression in epithelial tissues. Coulthard, M.G., Lickliter, J.D., Subanesan, N., Chen, K., Webb, G.C., Lowry, A.J., Koblar, S., Bottema, C.D., Boyd, A.W. Growth Factors (2001)
- Eph receptors are negatively controlled by protein tyrosine phosphatase receptor type O. Shintani, T., Ihara, M., Sakuta, H., Takahashi, H., Watakabe, I., Noda, M. Nat. Neurosci. (2006)
- Excitatory Eph receptors and adhesive ephrin ligands. Klein, R. Curr. Opin. Cell Biol. (2001)
- An Eph receptor regulates integrin activity through R-Ras. Zou, J.X., Wang, B., Kalo, M.S., Zisch, A.H., Pasquale, E.B., Ruoslahti, E. Proc. Natl. Acad. Sci. U.S.A. (1999)
- EphA4 is not required for Purkinje cell compartmentation. Karam, S.D., Dottori, M., Ogawa, K., Henderson, J.T., Boyd, A.W., Pasquale, E.B., Bothwell, M. Brain Res. Dev. Brain Res. (2002)
- Expression analysis of the Epha1 receptor tyrosine kinase and its high-affinity ligands Efna1 and Efna3 during early mouse development. Duffy, S.L., Steiner, K.A., Tam, P.P., Boyd, A.W. Gene Expr. Patterns (2006)
- The Eek receptor, a member of the Eph family of tyrosine protein kinases, can be activated by three different Eph family ligands. Park, S., Sánchez, M.P. Oncogene (1997)
- Eph-ephrin A system regulates murine blastocyst attachment and spreading. Fujii, H., Tatsumi, K., Kosaka, K., Yoshioka, S., Fujiwara, H., Fujii, S. Dev. Dyn. (2006)
- A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A. Dodelet, V.C., Pazzagli, C., Zisch, A.H., Hauser, C.A., Pasquale, E.B. J. Biol. Chem. (1999)
- mRNA expression of ephrins and Eph receptor tyrosine kinases in the neonatal and adult mouse central nervous system. Liebl, D.J., Morris, C.J., Henkemeyer, M., Parada, L.F. J. Neurosci. Res. (2003)
- Competition between retinal ganglion axons for targets under the servomechanism model explains abnormal retinocollicular projection of Eph receptor-overexpressing or ephrin-lacking mice. Honda, H. J. Neurosci. (2003)