Gene Review:
Efnb2 - ephrin B2
Mus musculus
Synonyms:
ELF-2, EPH-related receptor tyrosine kinase ligand 5, Elf2, Ephrin-B2, Epl5, ...
- Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth. Noren, N.K., Lu, M., Freeman, A.L., Koolpe, M., Pasquale, E.B. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells. Oike, Y., Ito, Y., Hamada, K., Zhang, X.Q., Miyata, K., Arai, F., Inada, T., Araki, K., Nakagata, N., Takeya, M., Kisanuki, Y.Y., Yanagisawa, M., Gale, N.W., Suda, T. Blood (2002)
- Ephrin-B2 overexpression enhances integrin-mediated ECM-attachment and migration of B16 melanoma cells. Meyer, S., Hafner, C., Guba, M., Flegel, S., Geissler, E.K., Becker, B., Koehl, G.E., Orsó, E., Landthaler, M., Vogt, T. Int. J. Oncol. (2005)
- Expression of EphA4 in developing inner ears of the mouse and guinea pig. van Heumen, W.R., Claxton, C., Pickles, J.O. Hear. Res. (2000)
- Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Foo, S.S., Turner, C.J., Adams, S., Compagni, A., Aubyn, D., Kogata, N., Lindblom, P., Shani, M., Zicha, D., Adams, R.H. Cell (2006)
- Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Urness, L.D., Sorensen, L.K., Li, D.Y. Nat. Genet. (2000)
- Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Gerety, S.S., Wang, H.U., Chen, Z.F., Anderson, D.J. Mol. Cell (1999)
- Altered Gene Expression Related to Glomerulogenesis and Podocyte Structure in Early Diabetic Nephropathy of db/db Mice and Its Restoration by Pioglitazone. Makino, H., Miyamoto, Y., Sawai, K., Mori, K., Mukoyama, M., Nakao, K., Yoshimasa, Y., Suga, S. Diabetes (2006)
- Ephrin-B2 induces migration of endothelial cells through the phosphatidylinositol-3 kinase pathway and promotes angiogenesis in adult vasculature. Maekawa, H., Oike, Y., Kanda, S., Ito, Y., Yamada, Y., Kurihara, H., Nagai, R., Suda, T. Arterioscler. Thromb. Vasc. Biol. (2003)
- Ephrin-B2 forward signaling regulates somite patterning and neural crest cell development. Davy, A., Soriano, P. Dev. Biol. (2007)
- Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development. Dravis, C., Yokoyama, N., Chumley, M.J., Cowan, C.A., Silvany, R.E., Shay, J., Baker, L.A., Henkemeyer, M. Dev. Biol. (2004)
- ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites. Bergemann, A.D., Cheng, H.J., Brambilla, R., Klein, R., Flanagan, J.G. Mol. Cell. Biol. (1995)
- Lac z Histochemistry and immunohistochemistry reveal ephrin-B ligand expression in the inner ear. Bianchi, L.M., Dinsio, K., Davoli, K., Gale, N.W. J. Histochem. Cytochem. (2002)
- Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development. Cowan, C.A., Yokoyama, N., Saxena, A., Chumley, M.J., Silvany, R.E., Baker, L.A., Srivastava, D., Henkemeyer, M. Dev. Biol. (2004)
- Global gene expression analysis in the bones reveals involvement of several novel genes and pathways in mediating an anabolic response of mechanical loading in mice. Xing, W., Baylink, D., Kesavan, C., Hu, Y., Kapoor, S., Chadwick, R.B., Mohan, S. J. Cell. Biochem. (2005)
- Crystal structure of the ephrin-B1 ectodomain: implications for receptor recognition and signaling. Nikolov, D.B., Li, C., Barton, W.A., Himanen, J.P. Biochemistry (2005)
- Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm. Williams, S.E., Mann, F., Erskine, L., Sakurai, T., Wei, S., Rossi, D.J., Gale, N.W., Holt, C.E., Mason, C.A., Henkemeyer, M. Neuron (2003)
- The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. Mui, S.H., Hindges, R., O'Leary, D.D., Lemke, G., Bertuzzi, S. Development (2002)
- Expression of Ephs and ephrins in developing mouse inner ear. Pickles, J.O. Hear. Res. (2003)
- EphB1-mediated cell migration requires the phosphorylation of paxillin at Tyr-31/Tyr-118. Vindis, C., Teli, T., Cerretti, D.P., Turner, C.E., Huynh-Do, U. J. Biol. Chem. (2004)
- EphA4 is not required for Purkinje cell compartmentation. Karam, S.D., Dottori, M., Ogawa, K., Henderson, J.T., Boyd, A.W., Pasquale, E.B., Bothwell, M. Brain Res. Dev. Brain Res. (2002)
- The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway. Noren, N.K., Foos, G., Hauser, C.A., Pasquale, E.B. Nat. Cell Biol. (2006)
- Purification, crystallization and preliminary characterization of an Eph-B2/ephrin-B2 complex. Himanen, J.P., Nikolov, D.B. Acta Crystallogr. D Biol. Crystallogr. (2002)