Gene Review:
Fosl2 - fos-like antigen 2
Mus musculus
Synonyms:
FRA-2, Fos-related antigen 2, Fra-2, Fra2
Aziz,
Manabe,
Yoneda,
Gordon,
Turque,
Ogita,
McMahon,
Miller,
Schumacher,
Garrington,
O'Callaghan,
Nakamichi,
Uhlik,
Mercier,
Johnson,
Cuevas,
Yang,
Pennypacker,
Cook,
Benkovic,
- Role of the Fos family members, c-Fos, Fra-1 and Fra-2, in the regulation of cell motility. Tkach, V., Tulchinsky, E., Lukanidin, E., Vinson, C., Bock, E., Berezin, V. Oncogene (2003)
- Long-term induction of Fos-related antigen-2 after methamphetamine-, methylenedioxymethamphetamine-, 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine- and trimethyltin-induced brain injury. Pennypacker, K.R., Yang, X., Gordon, M.N., Benkovic, S., Miller, D., O'Callaghan, J.P. Neuroscience (2000)
- The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis. Reich, N., Maurer, B., Akhmetshina, A., Venalis, P., Dees, C., Zerr, P., Palumbo, K., Zwerina, J., Nevskaya, T., Gay, S., Distler, O., Schett, G., Distler, J.H. Arthritis Rheum. (2010)
- Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB. Barton, K., Muthusamy, N., Chanyangam, M., Fischer, C., Clendenin, C., Leiden, J.M. Nature (1996)
- The binding of a Fos/Jun heterodimer can completely disrupt the structure of a nucleosome. Ng, K.W., Ridgway, P., Cohen, D.R., Tremethick, D.J. EMBO J. (1997)
- Tissue-specific transgenic knockdown of Fos-related antigen 2 (Fra-2) expression mediated by dominant negative Fra-2. Smith, M., Burke, Z., Humphries, A., Wells, T., Klein, D., Carter, D., Baler, R. Mol. Cell. Biol. (2001)
- The repertoire of fos and jun proteins expressed during the G1 phase of the cell cycle is determined by the duration of mitogen-activated protein kinase activation. Cook, S.J., Aziz, N., McMahon, M. Mol. Cell. Biol. (1999)
- The AP1 transcription factor Fra2 is required for efficient cartilage development. Karreth, F., Hoebertz, A., Scheuch, H., Eferl, R., Wagner, E.F. Development (2004)
- The gene encoding the Fos-related antigen 2 (Fosl2) maps to mouse chromosome 5. Poirier, C., Lalouette, A., Foletta, V.C., Cohen, D.R., Guénet, J.L. Mamm. Genome (1997)
- Attenuated expression of the serum responsive T1 gene in ras transformed fibroblasts due to the inhibition of c-fos gene activity. Kessler, R., Zacharova-Albinger, A., Laursen, N.B., Kalousek, M., Klemenz, R. Oncogene (1999)
- Cyclic AMP stimulates a JunD/Fra-2 AP-1 complex and inhibits the proliferation of interleukin-6-dependent cell lines. Rezzonico, R., Loubat, A., Lallemand, D., Pfarr, C.M., Far, D.F., Proudfoot, A., Rossi, B., Ponzio, G. Oncogene (1995)
- Cloning and characterisation of the mouse fra-2 gene. Foletta, V.C., Sonobe, M.H., Suzuki, T., Endo, T., Iba, H., Cohen, D.R. Oncogene (1994)
- Opposing activities of c-Fos and Fra-2 on AP-1 regulated transcriptional activity in mouse keratinocytes induced to differentiate by calcium and phorbol esters. Rutberg, S.E., Saez, E., Lo, S., Jang, S.I., Markova, N., Spiegelman, B.M., Yuspa, S.H. Oncogene (1997)
- Possible role for the FosB/JunD AP-1 transcription factor complex in glutamate-mediated excitotoxicity in cultured cerebellar granule cells. Lidwell, K., Griffiths, R. J. Neurosci. Res. (2000)
- Fra-2-positive autoregulatory loop triggered by mitogen-activated protein kinase (MAPK) and Fra-2 phosphorylation sites by MAPK. Murakami, M., Ui, M., Iba, H. Cell Growth Differ. (1999)
- Roles of adenosine receptors in the regulation of kainic acid-induced neurotoxic responses in mice. Lee, H.K., Choi, S.S., Han, K.J., Han, E.J., Suh, H.W. Brain Res. Mol. Brain Res. (2004)
- The antioxidant, rather than prooxidant, activities of quercetin on normal cells: quercetin protects mouse thymocytes from glucose oxidase-mediated apoptosis. Lee, J.C., Kim, J., Park, J.K., Chung, G.H., Jang, Y.S. Exp. Cell Res. (2003)
- Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP-1, NF-kappaB, and NF-IL6 in raw 264.7 macrophage cells. Wong, S.S., Zhou, H.R., Pestka, J.J. J. Toxicol. Environ. Health Part A (2002)
- MEKK1 regulates the AP-1 dimer repertoire via control of JunB transcription and Fra-2 protein stability. Cuevas, B.D., Uhlik, M.T., Garrington, T.P., Johnson, G.L. Oncogene (2005)
- Transcriptional Regulation of the Cholesterol Side Chain Cleavage Cytochrome P450 Gene (CYP11A1) Revisited: Binding of GATA, Cyclic Adenosine 3',5'-Monophosphate Response Element-Binding Protein and Activating Protein (AP)-1 Proteins to a Distal Novel Cluster of cis-Regulatory Elements Potentiates AP-2 and Steroidogenic Factor-1-Dependent Gene Expression in the Rodent Placenta and Ovary. Sher, N., Yivgi-Ohana, N., Orly, J. Mol. Endocrinol. (2007)
- Difference in transcriptional regulatory function between c-Fos and Fra-2. Suzuki, T., Okuno, H., Yoshida, T., Endo, T., Nishina, H., Iba, H. Nucleic Acids Res. (1991)
- Parathyroid hormone stimulates fra-2 expression in osteoblastic cells in vitro and in vivo. McCauley, L.K., Koh-Paige, A.J., Chen, H., Chen, C., Ontiveros, C., Irwin, R., McCabe, L.R. Endocrinology (2001)
- Rapid effects of triiodothyronine on immediate-early gene expression in Schwann cells. Mercier, G., Turque, N., Schumacher, M. Glia (2001)
- Occupancy and composition of proteins bound to the AP-1 sites in the glucocorticoid receptor and c-jun promoters after glucocorticoid treatment and in different cell types. Barrett, T.J., Vedeckis, W.V. Receptors & signal transduction. (1996)
- Differential expression and phosphorylation of particular fos family members by kainate in nuclear and cytosolic fractions of murine hippocampus. Manabe, T., Kitayama, T., Ogita, K., Yoneda, Y. Neuroscience (2000)
- Differential in vitro degradation of particular Fos family members expressed by kainic acid in nuclear and cytosolic fractions of murine hippocampus. Yoneda, Y., Nakamichi, N., Manabe, T., Ogita, K. J. Neurosci. Res. (2001)